List of works by Stanley Perlman

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

scientific article published on 03 August 2020

A SARS-CoV-specific protein enhances virulence of an attenuated strain of mouse hepatitis virus

scientific article published in January 2006

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.

scientific article

A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus

scientific article

A study of foldback DNA

scientific article published on May 1, 1976

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

scientific article

ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia

scientific article

Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus

scientific article published on 01 November 1995

Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice

scientific article published on 21 November 2011

Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

scientific article published on 6 June 2016

Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

scientific article published on 10 November 2016

Analysis of Xenopus laevis ovary and somatic cell polyadenylated RNA by molecular hybridization

scientific article published on March 1, 1978

Animal models for COVID-19

scientific article published on 23 September 2020

Another Decade, Another Coronavirus

scientific article published on 24 January 2020

Antibody Response and Disease Severity in Healthcare Worker MERS Survivors.

scientific article published on June 2016

Antibody-mediated protection against cytotoxic T-cell escape in coronavirus-induced demyelination

scientific article published on November 2003

Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus

scientific article

Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infection

scientific article

Bystander CD4 T cells do not mediate demyelination in mice infected with a neurotropic coronavirus

scientific article published on 01 April 2003

Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system

scientific article published on 01 August 2002

Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis.

scientific article

CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus

scientific article

CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination.

scientific article published in August 2000

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

scientific article published on 09 November 2020

Cell receptor-independent infection by a neurotropic murine coronavirus ⬇️

scientific article published on November 1, 1992

Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein

scientific article published on 10 April 2013

Confronting the persisting threat of the Middle East respiratory syndrome to global health security

scientific article published on 03 July 2019

Congenital viral infections of the brain: lessons learned from lymphocytic choriomeningitis virus in the neonatal rat.

scientific article

Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity

scientific article published on 19 April 2020

Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells.

scientific article published in May 1994

Coronaviruses post-SARS: update on replication and pathogenesis

scientific article

Coronaviruses: an overview of their replication and pathogenesis.

scientific article

Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection.

scientific article

Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

scientific article

Cytomegalovirus transmission in a Midwest day care center: possible relationship to child care practices

scientific article published on 01 July 1986

DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice

scientific article

DNA—RNA hybridization ⬇️

scientific article published on November 6, 1975

De novo recruitment of antigen-experienced and naive T cells contributes to the long-term maintenance of antiviral T cell populations in the persistently infected central nervous system

scientific article

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Detection of a murine coronavirus nonstructural protein encoded in a downstream open reading frame.

scientific article

Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor

scientific article published on 06 August 2013

Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R

scientific article

Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection

scientific article published on 11 February 2020

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.

scientific article published on February 2016

Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain ⬇️

scientific article published on October 1, 1990

Efficacy of an Automated Multiple Emitter Whole-Room Ultraviolet-C Disinfection System Against Coronaviruses MHV and MERS-CoV.

scientific article published on 28 January 2016

Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein

scientific article published on October 2003

Enhancement of murine coronavirus replication by severe acute respiratory syndrome coronavirus protein 6 requires the N-terminal hydrophobic region but not C-terminal sorting motifs

scientific article published on August 2007

Equine Immunoglobulin and Equine Neutralizing F(ab')₂ Protect Mice from West Nile Virus Infection

scientific article

Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice ⬇️

scientific article

Fusiform bacterial sepsis. Metastases with osteomyelitis and hepatic abscess occurring in a chaotic family.

scientific article published in September 1989

Gammadelta T cell response induced by vaginal Herpes simplex 2 infection

scientific article published on 01 November 1999

HCoV-OC43-induced encephalitis is in part immune-mediated

scientific article published in January 2006

High Prevalence of MERS-CoV Infection in Camel Workers in Saudi Arabia

scientific article published on 30 October 2018

High-magnitude, virus-specific CD4 T-cell response in the central nervous system of coronavirus-infected mice.

scientific article

Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis

scientific article

Human coronavirus 229E infects polarized airway epithelia from the apical surface

scientific article published on October 2000

Human coronavirus EMC is not the same as severe acute respiratory syndrome coronavirus

scientific article published on 15 January 2013

Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo

scientific article published in February 2016

IFN-gamma-mediated suppression of coronavirus replication in glial-committed progenitor cells

scientific article published on 06 December 2008

IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis

scientific article

Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirus

scientific article published on 01 April 1995

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

scientific article

Identification of putative polymerase gene product in cells infected with murine coronavirus A59

scientific article published on 01 April 1987

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.

scientific article

Identification of the spinal cord as a major site of persistence during chronic infection with a murine coronavirus.

scientific article published on April 1990

Immune response to a murine coronavirus: identification of a homing receptor-negative CD4+ T cell subset that responds to viral glycoproteins.

scientific article published in April 1992

Immune response to the immunodominant epitope of mouse hepatitis virus is polyclonal, but functionally monospecific in C57Bl/6 mice.

scientific article published in March 1999

Immune responses in influenza A virus and human coronavirus infections: an ongoing battle between the virus and host

scientific article published on 20 November 2017

Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

scientific article

Immunopathogenesis of coronavirus infections: implications for SARS.

scientific article

Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus

scientific article

In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.

scientific article published on 31 January 2017

Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization

scientific article

Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival

scientific article

Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events

scientific article published on 01 July 1992

Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections

scientific article

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

scientific article

Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus.

scientific article published on November 2006

MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis

scientific article published on 25 May 2016

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.

scientific article published on 5 March 2018

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

scientific article published on 25 January 2018

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

scientific article published in 2022

MHV S peplomer protein expressed by a recombinant vaccinia virus vector exhibits IgG Fc-receptor activity ⬇️

scientific article published on January 1, 1992

MHV nucleocapsid synthesis in the presence of cycloheximide and accumulation of negative strand MHV RNA

scientific article published on 01 December 1986

Maturation and localization of macrophages and microglia during infection with a neurotropic murine coronavirus

scientific article published on 12 October 2007

Measurement of CD8 and CD4 T Cell Responses in Mouse Lungs

scientific article published on 20 March 2014

Microglia are required for protection against lethal coronavirus encephalitis in mice

scientific article published on 29 January 2018

Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection

scientific article published on 14 September 2020

Middle East Respiratory Syndrome - advancing the public health and research agenda on MERS - lessons from the South Korea outbreak

scientific article published on 10 June 2015

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4.

scientific article published on 20 October 2015

Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice

scientific article published on 03 November 2020

Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus

scientific article published on 26 August 2016

Middle East respiratory syndrome

scientific article published on 3 June 2015

Middle East respiratory syndrome

scientific article published on 04 March 2020

Middle East respiratory syndrome and severe acute respiratory syndrome

scientific article published on 4 February 2016

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

scientific article

Middle East respiratory syndrome in the shadow of Ebola

scientific article published on 13 January 2015

Middle East respiratory syndrome vaccines

scientific article published on 07 April 2016

Mitochondrial Protein Synthesis: RNA with the Properties of Eukaryotic Messenger RNA ⬇️

scientific article published on February 1, 1973

Mitochondrial protein synthesis: resistance to emetine and response to RNA synthesis inhibitors.

scientific article published in August 1970

Mouse hepatitis virus does not induce Beta interferon synthesis and does not inhibit its induction by double-stranded RNA.

scientific article published on November 2006

Mouse hepatitis virus.

scientific article

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice

scientific article published on 27 March 2017

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

scientific article published on 17 January 2020

Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus

scientific article

Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis

scientific article

Murine cytomegalovirus genomic material in marrow cells: relation to altered leukocyte counts during sublethal infection of mice

scientific article published on 01 February 1987

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.

scientific article published on 18 January 2006

Not your usual tRNA synthetase: hWARS serves as an enterovirus entry factor

scientific article published on 15 October 2018

Oligodendrocytes that survive acute coronavirus infection induce prolonged inflammatory responses in the CNS

scientific article published on 22 June 2020

Pandemic origins and a One Health approach to preparedness and prevention: Solutions based on SARS-CoV-2 and other RNA viruses

scientific article published in 2022

Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model

scientific article published on 24 November 2016

Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection

scientific article published on 18 March 2015

Pathogenesis of acute and chronic central nervous system infection with variants of mouse hepatitis virus, strain JHM.

scientific article published on January 2007

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

scientific article published on 2 May 2017

Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis

scientific article

Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.

scientific article

Person-to-person spread of the MERS coronavirus--an evolving picture.

scientific article published in August 2013

Preferential infection of mature dendritic cells by mouse hepatitis virus strain JHM

scientific article

Preferential infection of mature dendritic cells by the JHM strain of mouse hepatitis virus

scientific article published on January 2006

Presence of tadpole and adult globin RNA sequences in oocytes of Xenopus laevis ⬇️

scientific article published on September 1, 1977

Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

scientific article

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

scientific article

Protection against CTL escape and clinical disease in a murine model of virus persistence

scientific article published in August 2003

Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

scientific article

Protein-synthesizing Structures associated with Mitochondria

scientific article published in Nature

Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism

scientific article published on 10 October 2016

Pseudomonas bursitis: inoculation from a catfish

Public health: Broad reception for coronavirus

scientific article published in March 2013

Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage

scientific article published on November 2006

Rapid generation of a mouse model for Middle East respiratory syndrome

scientific article

Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection

scientific article published on 19 February 2014

Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants

scientific article published on 19 October 2016

Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses.

scientific article published on 4 August 2017

Regional localization of virus in the central nervous system of mice persistently infected with murine coronavirus JHM.

scientific article published in October 1988

Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus

scientific article

Research Driven by Curiosity: The Journey from Basic Molecular Biology and Virology to Studies of Human Pathogenic Coronaviruses

scientific article published on 14 July 2015

Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease

scientific article published on 26 August 2009

Role of IFN-gamma responsiveness in CD8 T-cell-mediated viral clearance and demyelination in coronavirus-infected mice

scientific article published on 21 December 2007

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis.

scientific article

Role of regulatory T cells in coronavirus-induced acute encephalitis

scientific article published on 11 January 2009

Roles of regulatory T cells and IL-10 in virus-induced demyelination

scientific article published on 4 January 2017

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

scientific article published in Nature Communications

Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses.

scientific article published in May 2018

Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.

scientific article

Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2.

scientific article published on 21 May 2008

Severe acute respiratory syndrome coronavirus protein 6 accelerates murine coronavirus infections

scientific article published on 15 November 2006

Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism.

scientific article published on 30 April 2008

Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication

scientific article published on 17 December 2008

Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates

scientific article

Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection.

scientific article

Simultaneous Intranasal/Intravascular Antibody Labeling of CD4+ T Cells in Mouse Lungs

scientific article published on January 2017

Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

scientific article

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

scientific article published on 07 April 2020

Spread of MERS to South Korea and China

scientific article published on 4 June 2015

Spread of a neurotropic murine coronavirus into the CNS via the trigeminal and olfactory nerves

scientific article published on 01 June 1989

Structural Basis for the Identification of the N-Terminal Domain of Coronavirus Nucleocapsid Protein as an Antiviral Target

scientific article

Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes

scientific article

Structural and biological basis of CTL escape in coronavirus-infected mice

scientific article

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element.

scientific article published on 6 March 2018

T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice

scientific article

T cell-mediated immune response to respiratory coronaviruses

scientific article published on August 2014

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

scientific article published on 13 December 2016

The Middle East respiratory syndrome--how worried should we be?

scientific article published on 20 August 2013

The N-terminal region of severe acute respiratory syndrome coronavirus protein 6 induces membrane rearrangement and enhances virus replication.

scientific article

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

The cellular redox environment alters antigen presentation

scientific article

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression.

scientific article published on 16 May 2019

The coronavirus nucleocapsid protein is ADP-ribosylated.

scientific article

The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis

scientific article

The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM.

scientific article published in May 1993

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

scientific article published on 2 March 2020

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.

scientific article

Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection

scientific article published on 26 December 2012

Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb.

scientific article published in December 1993

Utilization of messenger in adenovirus-2-infected cells at normal and elevated temperatures

scientific article published on 01 August 1972

Vaccine against Middle East respiratory syndrome coronavirus

Very diverse CD8 T cell clonotypic responses after virus infections

scientific article published in March 2004

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis.

scientific article published on 18 December 2017

Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus

scientific article

Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice

scientific article

Virus Infection and Titration of SARS-CoV in Mouse Lung

scientific article published on 20 March 2014

Virus-induced demyelination in nude mice is mediated by gamma delta T cells.

scientific article published on October 2002

Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.

scientific article published on 19 June 2017

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis.

scientific article

Virus-specific antibody, in the absence of T cells, mediates demyelination in mice infected with a neurotropic coronavirus

scientific article

Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection

scientific article

Virus-specific regulatory T cells ameliorate encephalitis by repressing effector T cell functions from priming to effector stages

scientific article

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