List of works - Craig S. Nunemaker

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

scientific article

A Putative Prohibitin-Calcium Nexus in <i>β</i>-Cell Mitochondria and Diabetes

scientific article published on 08 October 2020

A novel fluorescence imaging approach for comparative measurements of pancreatic islet function in vitro ⬇️

scientific article published on January 1, 2011

A practical guide to rodent islet isolation and assessment

scientific article

AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets

scientific article

An Automated Perifusion System for Modifying Cell Culture Conditions over Time

scientific article

An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes

scientific article

Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion

scientific article

Calcium current subtypes in GnRH neurons

scientific article

Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro

scientific article published on 18 February 2020

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice ⬇️

scientific article published on July 8, 2013

Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes

scientific article

Comparison of metabolic oscillations from mouse pancreatic beta cells and islets

scientific article

Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse

scientific article

Considerations for Defining Cytokine Dose, Duration, and Milieu That Are Appropriate for Modeling Chronic Low-Grade Inflammation in Type 2 Diabetes

scientific article

Dose-dependent switch in response of gonadotropin-releasing hormone (GnRH) neurons to GnRH mediated through the type I GnRH receptor

scientific article

Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.

scientific article

Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons

scientific article

Evidence of diminished glucose stimulation and endoplasmic reticulum function in nonoscillatory pancreatic islets

scientific article

Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling ⬇️

scientific article published on August 25, 2010

Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets

scientific article

Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms

scientific article published on 30 June 2006

Glucose-induced release of nitric oxide from mouse pancreatic islets as detected with nitric oxide-selective glass microelectrodes

scientific article

Gonadotropin-releasing hormone neurons generate interacting rhythms in multiple time domains

scientific article

Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function

scientific article

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

scientific article

Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells

scientific article

Insulin secretion in the conscious mouse is biphasic and pulsatile

scientific article

Intact pancreatic islets and dispersed beta-cells both generate intracellular calcium oscillations but differ in their responsiveness to glucose

scientific article published on 16 September 2019

Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice

scientific article

Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes ⬇️

scientific article published on August 29, 2012

Mechanisms underlying episodic gonadotropin-releasing hormone secretion

scientific article

Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.

scientific article

Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

scientific article

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

scientific article

Prenatal androgen exposure programs metabolic dysfunction in female mice

scientific article

Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation

scientific article

STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

scientific article

Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling ⬇️

scientific article published on June 5, 2012

Steroid regulation of GnRH neurons

scientific article

Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets

scientific article

The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes

scientific article

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

scientific article

Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice

scientific article

Vesicular nucleotide transporter-mediated ATP release regulates insulin secretion

scientific article

Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion.

scientific article

List of works by Craig S. Nunemaker

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

A Putative Prohibitin-Calcium Nexus in <i>β</i>-Cell Mitochondria and Diabetes

A novel fluorescence imaging approach for comparative measurements of pancreatic islet function in vitro ⬇️

A practical guide to rodent islet isolation and assessment

AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets

An Automated Perifusion System for Modifying Cell Culture Conditions over Time

An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes

Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion

Calcium current subtypes in GnRH neurons

Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice ⬇️

Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes

Comparison of metabolic oscillations from mouse pancreatic beta cells and islets

Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse

Considerations for Defining Cytokine Dose, Duration, and Milieu That Are Appropriate for Modeling Chronic Low-Grade Inflammation in Type 2 Diabetes

Dose-dependent switch in response of gonadotropin-releasing hormone (GnRH) neurons to GnRH mediated through the type I GnRH receptor

Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.

Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons

Evidence of diminished glucose stimulation and endoplasmic reticulum function in nonoscillatory pancreatic islets

Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling ⬇️

Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets

Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms

Glucose-induced release of nitric oxide from mouse pancreatic islets as detected with nitric oxide-selective glass microelectrodes

Gonadotropin-releasing hormone neurons generate interacting rhythms in multiple time domains

Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells

Insulin secretion in the conscious mouse is biphasic and pulsatile

Intact pancreatic islets and dispersed beta-cells both generate intracellular calcium oscillations but differ in their responsiveness to glucose

Islet Hypersensitivity to Glucose Is Associated With Disrupted Oscillations and Increased Impact of Proinflammatory Cytokines in Islets From Diabetes-Prone Male Mice

Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes ⬇️

Mechanisms underlying episodic gonadotropin-releasing hormone secretion

Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.

Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

Prenatal androgen exposure programs metabolic dysfunction in female mice

Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation

STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling ⬇️

Steroid regulation of GnRH neurons

Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets

The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice

Vesicular nucleotide transporter-mediated ATP release regulates insulin secretion

Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion.