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List of works by Robert Lahue

A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice

scientific article

Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.

scientific article

CAG*CTG repeat instability in cultured human astrocytes

scientific article

Characterization of a DNA mismatch-binding activity in yeast extracts.

scientific article

Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae.

scientific article

Communication between polypeptide chains in aspartate transcarbamoylase. Conformational changes at the active sites of unliganded chains resulting from ligand binding to other chains

scientific article published in Journal of Biological Chemistry

Correction of large mispaired DNA loops by extracts of Saccharomyces cerevisiae

scientific article published in Journal of Biological Chemistry

DNA elements important for CAG*CTG repeat thresholds in Saccharomyces cerevisiae.

scientific article published on 24 February 2004

DNA polymerase delta, RFC and PCNA are required for repair synthesis of large looped heteroduplexes in Saccharomyces cerevisiae.

scientific article published on December 2004

DNA repair and trinucleotide repeat instability ⬇️

scientific article published on May 1, 2003

Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae

article

Efficient repair of large DNA loops in Saccharomyces cerevisiae

scientific article

Expansions of CAG.CTG repeats in immortalized human astrocytes.

scientific article

Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition.

scientific article

Genetic assays for triplet repeat instability in yeast

article

HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions

scientific article published on 08 September 2020

Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions ⬇️

scientific article published on February 21, 2012

Histone deacetylase complexes as caretakers of genome stability.

scientific article

Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats

scientific article (publication date: December 1999)

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

scientific article (publication date: 1996)

Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.

scientific article

MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions.

scientific article published on September 2017

New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.

scientific article

Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions.

scientific article published on 17 December 2013

Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae ⬇️

scientific article published on October 13, 1998

Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae

scientific article

Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.

scientific article published on 23 October 2006

RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility

RTEL1 inhibits trinucleotide repeat expansions and fragility.

scientific article published on 20 February 2014

Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae

scientific article

Rev1 enhances CAG.CTG repeat stability in Saccharomyces cerevisiae

article

Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.

scientific article

Stabilizing effects of interruptions on trinucleotide repeat expansions in Saccharomyces cerevisiae

scientific article

The 26S proteasome drives trinucleotide repeat expansions

scientific article

The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.

scientific article

The influence of quaternary structure on the active site of an oligomeric enzyme. Catalytic subunit of aspartate transcarbamoylase

scientific article published in Journal of Biological Chemistry

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