Search filters

List of works by David Gervais

Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates

scientific article published on 21 September 2015

Capillary isoelectric focusing of a difficult-to-denature tetrameric enzyme using alkylurea-urea mixtures

scientific article

Characterization of the UK anthrax vaccine and human immunogenicity

scientific article published on 08 September 2020

Control of process-induced asparaginyl deamidation during manufacture of Erwinia chrysanthemi l-asparaginase

scientific article published in 2013

Enhancing immunogenicity of a 3'aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates

scientific article published on 2 April 2013

Higher-order structure and conformational change in biopharmaceuticals

Measurement of subvisible particulates in lyophilised Erwinia chrysanthemi L-asparaginase and relationship with clinical experience

scientific article published on 23 May 2014

Protein deamidation in biopharmaceutical manufacture: understanding, control and impact

article

Quality Control and Downstream Processing of Therapeutic Enzymes

scientific article published on 01 January 2019

Recombinant deamidated mutants of Erwinia chrysanthemi L-asparaginase have similar or increased activity compared to wild-type enzyme.

scientific article

Robust quantitation of basic-protein higher-order aggregates using size-exclusion chromatography

scientific article published on 7 March 2017

Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice

scientific article

Structural Characterisation of Non-Deamidated Acidic Variants of Erwinia chrysanthemi L-asparaginase Using Small-Angle X-ray Scattering and Ion-Mobility Mass Spectrometry.

scientific article published on 4 June 2015

Understanding the process-induced formation of minor conformational variants of Erwinia chrysanthemil-asparaginase

scientific article published on 19 December 2016

Validation of a 30-year-old process for the manufacture of L-asparaginase from Erwinia chrysanthemi

scientific article published on 21 August 2012

What makes a good new therapeutic L-asparaginase?

scientific article published on 24 September 2019

Paulina is supported by:

About Paulina

Help