Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Shannon Meeks

A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function

scientific article

A microengineered vascularized bleeding model that integrates the principal components of hemostasis.

scientific article

A subset of high-titer anti-factor VIII A2 domain antibodies is responsive to treatment with factor VIII.

scientific article published on 29 January 2016

Abnormalities of prothrombin: a review of the pathophysiology, diagnosis, and treatment

scientific article

Anti-C1 domain antibodies that accelerate factor VIII clearance contribute to antibody pathogenicity in a murine hemophilia A model

scientific article published on 13 August 2018

Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation

scientific article published on 11 September 2007

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies

scientific article published on 15 February 2013

Characterization of a genetically engineered mouse model of hemophilia A with complete deletion of the F8 gene

scientific article published on 20 November 2015

Development of factor VIII inhibitors in two patients with moderate haemophilia A.

scientific article

Discordance between platelet-supported and vesicle-supported factor VIII activity in the presence of anti-C2 domain inhibitory antibodies

scientific article published on 17 June 2020

Emerging benefits of Fc fusion technology in the context of recombinant factor VIII replacement therapy

scientific article published on 03 September 2020

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction

scientific article published on 26 September 2016

Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen-deuterium exchange mass spectrometry.

scientific article published on December 2013

Evaluation of factor VIII pharmacokinetics and anti-factor VIII antibodies in four boys with haemophilia A and a poor clinical response to factor VIII.

scientific article published in January 2011

Expanding the ortholog approach for hemophilia treatment complicated by factor VIII inhibitors

scientific article

Factor II, Factor V and Factor X Deficiencies

Factor VII Deficiency

Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein

scientific article

Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation

scientific article published on 09 June 2020

Hemophilia and inhibitors: current treatment options and potential new therapeutic approaches.

scientific article published on December 2016

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

scientific article published on 05 July 2016

High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance

scientific article

Immune tolerance induction in paediatric patients with haemophilia A and inhibitors receiving emicizumab prophylaxis

scientific article published on 02 August 2019

Innovating immune tolerance induction for haemophilia.

scientific article

Late immune tolerance induction in haemophilia A patients.

scientific article published on 7 January 2013

Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A.

scientific article published on 4 October 2017

Medical radiation exposure in children with bleeding disorders: an institutional experience.

scientific article published on 28 May 2012

Non-classical anti-factor VIII C2 domain antibodies are pathogenic in a murine in vivo bleeding model.

scientific article

Nonclassical anti-C2 domain antibodies are present in patients with factor VIII inhibitors

scientific article published on 21 May 2008

Platelet-Microcapsule Hybrids Leverage Contractile Force for Targeted Delivery of Hemostatic Agents.

scientific article published on 25 May 2017

Potentiation of thrombin generation in hemophilia A plasma by coagulation factor VIII and characterization of antibody-specific inhibition

scientific article published on 29 October 2012

Reduced bone formation in males and increased bone resorption in females drive bone loss in hemophilia A mice

scientific article published on 01 February 2019

Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach.

scientific article published on 30 April 2015

Should hemophilia treaters switch to albumin-free recombinant factor VIII concentrates

scientific article published on November 2006

Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes

scientific article

The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfaces

scientific article published on 16 March 2015

The diversity of the immune response to the A2 domain of human factor VIII

scientific article published on 24 January 2013

The evolution of factor VIIa in the treatment of bleeding in haemophilia with inhibitors

scientific article published on 05 September 2019

The national blueprint for future basic and translational research to understand factor VIII immunogenicity: NHLBI State of the Science Workshop on factor VIII inhibitors

scientific article published on 01 July 2019

The prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures prior to FVIII inhibitor development

scientific article published on 01 November 2020

Toward optimal therapy for inhibitors in hemophilia

scientific article

Toward optimal therapy for inhibitors in hemophilia.

scientific article

US Guidelines for immune tolerance induction in patients with haemophilia a and inhibitors

scientific article published on 02 June 2015

Use of factor VIII after inhibitor clearance in patients with moderate haemophilia A: a case series.

scientific article published on 21 April 2014

Paulina is supported by:

About Paulina

Help