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List of works by Robert A. Pearce

A model for intersegmental coordination in the leech nerve cord ⬇️

scientific article published on January 1, 1988

A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors

scientific article

Active and passive membrane properties and intrinsic kinetics shape synaptic inhibition in hippocampal CA1 pyramidal neurons.

scientific article published in August 2006

All together now.

scientific article published in May 2009

Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit

scientific article

Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo.

scientific article

Amnestic concentrations of etomidate modulate GABAA,slow synaptic inhibition in hippocampus

scientific article

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice

scientific article (publication date: October 2006)

Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.

scientific article published in March 2004

Barbiturates and the brain.

scientific article published in November 1999

Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness

scientific article

CPP impairs contextual learning at concentrations below those that block pyramidal neuron NMDARs and LTP in the CA1 region of the hippocampus

scientific article published in 2022

Concentration measures of volatile anesthetics in the aqueous phase using calcium sensitive electrodes ⬇️

scientific article published on June 1, 1998

Contrasting Effects of the γ-Aminobutyric Acid Type A Receptor β3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB.

scientific article published on 21 June 2016

Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro.

scientific article published on 17 September 2004

Different mechanisms for use-dependent depression of two GABAA-mediated IPSCs in rat hippocampus

scientific article published on 01 April 1995

Differential uptake of volatile agents into brain tissue in vitro. Measurement and application of a diffusion model to determine concentration profiles in brain slices.

scientific article published in July 2003

Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

scientific article published on June 2005

Doc2-mediated superpriming supports synaptic augmentation

article published in the Proceedings of the National Academy of Sciences of the United States of America

Dual actions of volatile anesthetics on GABA(A) IPSCs: dissociation of blocking and prolonging effects.

scientific article

Effects of halothane on GABA(A) receptor kinetics: evidence for slowed agonist unbinding.

scientific article

Enhancement of α5-containing γ-aminobutyric acid type A receptors by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6) is abolished by the β3(N265M) mutation.

scientific article

Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells

scientific article

Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor

scientific article

Exceptionally stable fluorous emulsions for the intravenous delivery of volatile general anesthetics

scientific article published on March 2012

Flow characterization and patch clamp dose responses using jet microfluidics in a tubeless microfluidic device.

scientific article

Fluoropolymer-based emulsions for the intravenous delivery of sevoflurane.

scientific article published on October 2008

Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture.

scientific article published on March 2007

GABA A,slow: causes and consequences.

scientific article published on 09 December 2010

GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus.

scientific article published on 10 December 2008

GABAA-mediated IPSCs in piriform cortex have fast and slow components with different properties and locations on pyramidal cells.

scientific article published on November 1997

Histamine Release Associated with Intravenous Delivery of a Fluorocarbon-Based Sevoflurane Emulsion in Canines ⬇️

scientific article published on January 18, 2011

Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem.

scientific article published in October 1993

Identification of a fluorescent general anesthetic, 1-aminoanthracene

scholarly article

Interactions between distinct GABA(A) circuits in hippocampus

scientific article published on 01 February 2000

Intersegmental coordination of leech swimming: comparison of in situ and isolated nerve cord activity with body wall movement.

scientific article published in May 1984

Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone

scientific article published in April 2003

Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations.

scientific article published in April 2012

Isoflurane impairs odour discrimination learning in rats: differential effects on short- and long-term memory ⬇️

scientific article published on January 17, 2012

Kinetic differences between synaptic and extrasynaptic GABA(A) receptors in CA1 pyramidal cells

scientific article published on 01 February 2000

Lipid-free Fluoropolymer-based Propofol Emulsions and Lipid Reversal of Propofol Anesthesia in Rats.

scientific article published on 3 March 2016

Measurement of NMDA Receptor Antagonist, CPP, in Mouse Plasma and Brain Tissue Following Systematic Administration Using Ion-Pair LCMS/MS

scientific article

Measurement of rCBF by H2 clearance: theoretical analysis of diffusion effects.

scientific article published in May 1982

Midazolam and atropine alter theta oscillations in the hippocampal CA1 region by modulating both the somatic and distal dendritic dipoles.

scientific article

Muscarinic blockade weakens interaction of gamma with theta rhythms in mouse hippocampus.

scientific article published in September 2007

Neural mechanisms generating the leech swimming rhythm: swim-initiator neurons excite the network of swim oscillator neurons

scientific article published on 01 August 1987

Physiological evidence for two distinct GABAA responses in rat hippocampus.

scientific article published in February 1993

Retrotrapezoid nucleus in the rat.

scientific article

Slowing of the hippocampal θ rhythm correlates with anesthetic-induced amnesia ⬇️

scientific article published on December 1, 2010

Spatiotemporal characteristics and pharmacological modulation of multiple gamma oscillations in the CA1 region of the hippocampus

scientific article

Specification of motoneurons from human embryonic stem cells.

scientific article

Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways

scientific article published on 06 August 2019

The differential effects of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane on extrasynaptic gamma-aminobutyric acid A receptors.

scientific article published in June 2005

The gamma-subunit governs the susceptibility of recombinant gamma-aminobutyric acid type A receptors to block by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N).

scientific article published on August 2005

The synaptic basis of GABAA,slow

scientific article published on 01 February 1998

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference

scientific article

Volatile anaesthetic enhancement of paired-pulse depression investigated in the rat hippocampus in vitro.

scientific article published in May 1996

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