List of works - Efrosini Kokkoli

A chitosan-hyaluronan-based hydrogel-hydrocolloid supports in vitro culture and differentiation of human mesenchymal stem/stromal cells.

scientific article published on 20 April 2015

Aptamer micelles targeting fractalkine-expressing cancer cells in vitro and in vivo.

scientific article

Binding of the fibronectin-mimetic peptide, PR_b, to alpha5beta1 on pig islet cells increases fibronectin production and facilitates internalization of PR_b functionalized liposomes

scientific article

Bioresorbable polymersomes for targeted delivery of cisplatin

scientific article published on 5 April 2013

Characterizing particulate drug-delivery carriers with atomic force microscopy.

scientific article

Collective and single-molecule interactions of alpha5beta1 integrins.

scientific article published in March 2004

DNA nanotubes and helical nanotapes via self-assembly of ssDNA-amphiphiles

scientific article published in January 2015

Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials.

scientific article published in March 2006

Design of an Aptamer-Amphiphile for the Detection of β-Lactoglobulin on a Liquid Crystal Interface

scientific article published on 25 October 2019

Developing U.S. oversight strategies for nanobiotechnology: learning from past oversight experiences.

scientific article published on January 2009

Development and characterization of an aptamer binding ligand of fractalkine using domain targeted SELEX.

scientific article

Divergent Mechanistic Avenues to an Aliphatic Polyesteracetal or Polyester from a Single Cyclic Esteracetal

Dual-ligand α5β1 and α6β4 integrin targeting enhances gene delivery and selectivity to cancer cells.

scientific article published on 16 February 2017

Effect of RGD secondary structure and the synergy site PHSRN on cell adhesion, spreading and specific integrin engagement.

scientific article published on 24 March 2006

Effect of Solvents on Interactions between Hydrophobic Self-Assembled Monolayers.

scientific article

Effect of linker and spacer on the design of a fibronectin-mimetic peptide evaluated via cell studies and AFM adhesion forces.

scientific article published on 12 August 2008

Effect of polyethylene glycol, alkyl, and oligonucleotide spacers on the binding, secondary structure, and self-assembly of fractalkine binding FKN-S2 aptamer-amphiphiles

scientific article published on 17 June 2014

Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.

scientific article published on 9 January 2012

Evaluating oversight of human drugs and medical devices: a case study of the FDA and implications for nanobiotechnology.

scientific article published on January 2009

Increasing cancer-specific gene expression by targeting overexpressed α5β1 integrin and upregulated transcriptional activity of NF-κB.

scientific article published on 12 February 2014

Interaction Forces between Hydrophobic and Hydrophilic Self-Assembled Monolayers

scientific article published on 01 October 2000

Introduction: The challenge of developing oversight approaches to nanobiotechnology

scientific article published on 01 January 2009

Mechanistic principles of nanoparticle evolution to zeolite crystals.

scientific article published on 16 April 2006

Microstructural optimization of a zeolite membrane for organic vapor separation.

scientific article published on 6 March 2003

On the TEM and AFM evidence of zeosil nanoslabs present during the synthesis of silicalite-1

scientific article published on 01 September 2004

PEGylated liposomal doxorubicin targeted to α5β1-expressing MDA-MB-231 breast cancer cells.

scientific article published on 29 February 2012

PR_b-targeted PEGylated liposomes for prostate cancer therapy.

scientific article

PR_b-targeted delivery of tumor necrosis factor-α by polymersomes for the treatment of prostate cancer

Patterned biomimetic membranes: effect of concentration and pH.

scientific article published in August 2005

Peptide targeted lipid nanoparticles for anticancer drug delivery.

scientific article published on 05 June 2012

Peptide- and aptamer-functionalized nanovectors for targeted delivery of therapeutics.

scientific article published on July 2009

Polymersomes functionalized via “click” chemistry with the fibronectin mimetic peptides PR_b and GRGDSP for targeted delivery to cells with different levels of α5β1 expression

Preparation and characterization of liposome-encapsulated plasmid DNA for gene delivery.

scientific article published on 9 July 2013

Recommendations for nanomedicine human subjects research oversight: an evolutionary approach for an emerging field

scientific article

Salt Responsive Morphologies of ssDNA-Based Triblock Polyelectrolytes in Semi-Dilute Regime: Effect of Volume Fractions and Polyelectrolyte Length.

scientific article published on 12 September 2017

Self-assembly of fibronectin mimetic peptide-amphiphile nanofibers

scientific article published on February 2010

Synthesis and characterization of reactive PEO–PMCL polymersomes

Targeted polymersome delivery of siRNA induces cell death of breast cancer cells dependent upon Orai3 protein expression

scientific article

Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide.

scientific article published on 19 September 2008

The design of peptide-amphiphiles as functional ligands for liposomal anticancer drug and gene delivery.

scientific article

The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes.

scientific article published in January 2014

Three-Dimensional Cell Entrapment as a Function of the Weight Percent of Peptide-Amphiphile Hydrogels.

scientific article published on 26 May 2015

Transfection mechanisms of polyplexes, lipoplexes, and stealth liposomes in α₅β₁ integrin bearing DLD-1 colorectal cancer cells.

scientific article published on 27 March 2014

pH-Sensitive PEGylated liposomes functionalized with a fibronectin-mimetic peptide show enhanced intracellular delivery to colon cancer cell.

scientific article published on August 2011

ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival

scientific article published on 01 December 2021

ssDNA-amphiphile architecture used to control dimensions of DNA nanotubes

scientific article published on 27 September 2019

List of works by Efrosini Kokkoli

A chitosan-hyaluronan-based hydrogel-hydrocolloid supports in vitro culture and differentiation of human mesenchymal stem/stromal cells.

Aptamer micelles targeting fractalkine-expressing cancer cells in vitro and in vivo.

Binding of the fibronectin-mimetic peptide, PR_b, to alpha5beta1 on pig islet cells increases fibronectin production and facilitates internalization of PR_b functionalized liposomes

Bioresorbable polymersomes for targeted delivery of cisplatin

Characterizing particulate drug-delivery carriers with atomic force microscopy.

Collective and single-molecule interactions of alpha5beta1 integrins.

DNA nanotubes and helical nanotapes via self-assembly of ssDNA-amphiphiles

Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials.

Design of an Aptamer-Amphiphile for the Detection of β-Lactoglobulin on a Liquid Crystal Interface

Developing U.S. oversight strategies for nanobiotechnology: learning from past oversight experiences.

Development and characterization of an aptamer binding ligand of fractalkine using domain targeted SELEX.

Divergent Mechanistic Avenues to an Aliphatic Polyesteracetal or Polyester from a Single Cyclic Esteracetal

Dual-ligand α5β1 and α6β4 integrin targeting enhances gene delivery and selectivity to cancer cells.

Effect of RGD secondary structure and the synergy site PHSRN on cell adhesion, spreading and specific integrin engagement.

Effect of Solvents on Interactions between Hydrophobic Self-Assembled Monolayers.

Effect of linker and spacer on the design of a fibronectin-mimetic peptide evaluated via cell studies and AFM adhesion forces.

Effect of polyethylene glycol, alkyl, and oligonucleotide spacers on the binding, secondary structure, and self-assembly of fractalkine binding FKN-S2 aptamer-amphiphiles

Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.

Evaluating oversight of human drugs and medical devices: a case study of the FDA and implications for nanobiotechnology.

Increasing cancer-specific gene expression by targeting overexpressed α5β1 integrin and upregulated transcriptional activity of NF-κB.

Interaction Forces between Hydrophobic and Hydrophilic Self-Assembled Monolayers

Introduction: The challenge of developing oversight approaches to nanobiotechnology

Mechanistic principles of nanoparticle evolution to zeolite crystals.

Microstructural optimization of a zeolite membrane for organic vapor separation.

On the TEM and AFM evidence of zeosil nanoslabs present during the synthesis of silicalite-1

PEGylated liposomal doxorubicin targeted to α5β1-expressing MDA-MB-231 breast cancer cells.

PR_b-targeted PEGylated liposomes for prostate cancer therapy.

PR_b-targeted delivery of tumor necrosis factor-α by polymersomes for the treatment of prostate cancer

Patterned biomimetic membranes: effect of concentration and pH.

Peptide targeted lipid nanoparticles for anticancer drug delivery.

Peptide- and aptamer-functionalized nanovectors for targeted delivery of therapeutics.

Polymersomes functionalized via “click” chemistry with the fibronectin mimetic peptides PR_b and GRGDSP for targeted delivery to cells with different levels of α5β1 expression

Preparation and characterization of liposome-encapsulated plasmid DNA for gene delivery.

Recommendations for nanomedicine human subjects research oversight: an evolutionary approach for an emerging field

Salt Responsive Morphologies of ssDNA-Based Triblock Polyelectrolytes in Semi-Dilute Regime: Effect of Volume Fractions and Polyelectrolyte Length.

Self-assembly of fibronectin mimetic peptide-amphiphile nanofibers

Synthesis and characterization of reactive PEO–PMCL polymersomes

Targeted polymersome delivery of siRNA induces cell death of breast cancer cells dependent upon Orai3 protein expression

Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide.

The design of peptide-amphiphiles as functional ligands for liposomal anticancer drug and gene delivery.

The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes.

Three-Dimensional Cell Entrapment as a Function of the Weight Percent of Peptide-Amphiphile Hydrogels.

Transfection mechanisms of polyplexes, lipoplexes, and stealth liposomes in α₅β₁ integrin bearing DLD-1 colorectal cancer cells.

pH-Sensitive PEGylated liposomes functionalized with a fibronectin-mimetic peptide show enhanced intracellular delivery to colon cancer cell.

ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival

ssDNA-amphiphile architecture used to control dimensions of DNA nanotubes