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List of works by Shayn Peirce

Adipose-derived stem cells from diabetic mice show impaired vascular stabilization in a murine model of diabetic retinopathy.

scientific article

Agent-based computational model of retinal angiogenesis simulates microvascular network morphology as a function of pericyte coverage.

scientific article published on 8 August 2017

Agent-based model illustrates the role of the microenvironment in regeneration in healthy and mdx skeletal muscle

scientific article published on 02 August 2018

Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks

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Agent-based model of therapeutic adipose-derived stromal cell trafficking during ischemia predicts ability to roll on P-selectin.

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An engineering design approach to systems biology

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Applications of computational models to better understand microvascular remodelling: a focus on biomechanical integration across scales.

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Arteriogenesis in murine adipose tissue is contingent on CD68+ /CD206+ macrophages.

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Arteriolar remodeling following ischemic injury extends from capillary to large arteriole in the microcirculation.

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Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Rarefaction and Estimation of Skeletal Muscle Perfusion in Peripheral Arterial Disease.

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Computational and mathematical modeling of angiogenesis

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Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients.

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Data-Driven Model Validation Across Dimensions

scientific article published on 04 March 2019

Design and implementation of a student-taught course on research in regenerative medicine

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Differential Effects of Processing Time and Duration of Collagenase Digestion on Human and Murine Fat Grafts

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Differential arterial/venous expression of NG2 proteoglycan in perivascular cells along microvessels: identifying a venule-specific phenotype.

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Dynamic, heterogeneous endothelial Tie2 expression and capillary blood flow during microvascular remodeling

scientific article published on 22 August 2017

Effect of Adipose-Derived Stem Cells on Head and Neck Squamous Cell Carcinoma.

scientific article published in January 2018

Effects of Collagenase Digestion and Stromal Vascular Fraction Supplementation on Volume Retention of Fat Grafts.

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EphB4 expression along adult rat microvascular networks: EphB4 is more than a venous specific marker.

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Exogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle ischemia model.

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Fibroblasts: Diverse Cells Critical to Biomaterials Integration

scientific article published on 13 June 2017

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

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Functional binding of human adipose-derived stromal cells: effects of extraction method and hypoxia pretreatment.

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Human adipose-derived stromal/stem cells demonstrate short-lived persistence after implantation in both an immunocompetent and an immunocompromised murine model

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IFATS collection: The role of human adipose-derived stromal cells in inflammatory microvascular remodeling and evidence of a perivascular phenotype

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Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth

scientific article published on 05 December 2018

In Silico and In Vivo Experiments Reveal M-CSF Injections Accelerate Regeneration Following Muscle Laceration

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Induction of microvascular network growth in the mouse mesentery

scientific article published on 10 October 2018

Inhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult rats

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Integration of experimental and computational approaches to sprouting angiogenesis.

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Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms.

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Ischemia-reperfusion injury in chronic pressure ulcer formation: a skin model in the rat.

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Klf4 has an unexpected protective role in perivascular cells within the microvasculature.

scientific article published on 6 April 2018

Macrophage Recruitment and Polarization During Collateral Vessel Remodeling in Murine Adipose Tissue.

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Macrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis

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Mechanotransduction in Blood and Lymphatic Vascular Development and Disease.

scientific article published on 10 November 2017

Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke

scientific article published on 21 December 2017

Methods to label, image, and analyze the complex structural architectures of microvascular networks

scientific article published on 17 January 2019

Microfluidic Technologies and Approaches for Studying the Microcirculation.

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Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing

scientific article published in Scientific Reports

Monocytes are recruited from venules during arteriogenesis in the murine spinotrapezius ligation model.

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Multi-cell agent-based simulation of the microvasculature to study the dynamics of circulating inflammatory cell trafficking.

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Multi-scale models of lung fibrosis

scientific article published on 11 May 2020

Multicellular computer simulation of morphogenesis: blastocoel roof thinning and matrix assembly in Xenopus laevis.

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Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.

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Oxygen Sensing Difluoroboron β-Diketonate Polylactide Materials with Tunable Dynamic Ranges for Wound Imaging.

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Paradoxical Adipose Hyperplasia and Cellular Effects After Cryolipolysis: A Case Report.

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Perivascular cell-specific knockout of the stem cell pluripotency gene Oct4 inhibits angiogenesis

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Perivascular cells along venules upregulate NG2 expression during microvascular remodeling.

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Preclinical Assessment of Safety and Efficacy of Fluorescent Dye for Detecting Dermal Injuries (the injuries were both abrasions and incision) in a Murine Model.

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Rapid analysis of vessel elements (RAVE): a tool for studying physiologic, pathologic and tumor angiogenesis.

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Rat mesentery exteriorization: a model for investigating the cellular dynamics involved in angiogenesis.

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Selective Activation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes Local Microvascular Network Growth

scientific article published on November 9, 2010

Spatial scaling in multiscale models: methods for coupling agent-based and finite-element models of wound healing

scientific article published on 09 April 2019

Targeting pericytes for angiogenic therapies.

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Toward a multi-scale computational model of arterial adaptation in hypertension: verification of a multi-cell agent based model.

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Vascular assembly in natural and engineered tissues.

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Vivarium: an interface and engine for integrative multiscale modeling in computational biology

scientific article published in 2022