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List of works by Dong-Gyu Jo

A hyaluronic acid-methotrexate conjugate for targeted therapy of rheumatoid arthritis

scientific article

Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system

scientific article

Alzheimer's disease and Notch signaling.

scientific article published on 22 October 2009

Assignment of the rat calcineurin inhibitor gene (Cain) to rat chromosome band 20p12 by fluorescence in situ hybridization

scientific article published on 01 January 2000

Atf3 induction is a therapeutic target for obesity and metabolic diseases

scientific article published on 14 September 2018

Bioreducible shell-cross-linked hyaluronic acid nanoparticles for tumor-targeted drug delivery

scientific article

Calcium binding of ARC mediates regulation of caspase 8 and cell death

scientific article

Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging

scholarly article

Calsenilin contributes to neuronal cell death in ischemic stroke.

scientific article published on 27 December 2012

Cancer therapy using ultrahigh hydrophobic drug-loaded graphene derivatives

scientific article

Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis

scientific article

Cell reprogramming using extracellular vesicles from differentiating stem cells into white/beige adipocytes

scientific article published on 25 March 2020

Cerebral transcriptome analysis reveals age-dependent progression of neuroinflammation in P301S mutant tau transgenic male mice

scientific article published on 11 April 2019

Cks1 regulates human hepatocellular carcinoma cell progression through osteopontin expression

scientific article published on 26 November 2018

Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion

scientific article (publication date: 27 June 1997)

Clusterin contributes to early stage of Alzheimer's disease pathogenesis

scientific article published on 29 October 2018

Contribution of gamma-secretase to calcium-mediated cell death.

scientific article

Contribution of presenilin/gamma-secretase to calsenilin-mediated apoptosis.

scientific article published in May 2003

Cytotoxicity of lipid-soluble ginseng extracts is attenuated by plasma membrane redox enzyme NQO1 through maintaining redox homeostasis and delaying apoptosis in human neuroblastoma cells

scientific article published on 05 October 2016

Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment

scientific article

Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer's Disease

scientific article published on 21 November 2017

Down-regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia

scientific journal article

Effect of tumor necrosis factor-related apoptosis-inducing ligand on the reduction of joint inflammation in experimental rheumatoid arthritis

scientific article published on 20 November 2009

Effects of chronic alcohol consumption on expression levels of APP and Aβ-producing enzymes.

scientific article published in February 2011

Emerging Roles of Sirtuins in Ischemic Stroke.

scientific article published on 27 June 2017

Emerging roles of the γ-secretase-notch axis in inflammation.

scientific article

Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity

scientific article published in September 2003

Evidence for a detrimental role of TLR8 in ischemic stroke

scientific article published on 24 October 2013

Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke

scientific article published on 14 January 2017

Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death

scientific article

Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke.

scientific article published on 16 October 2013

Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.

scientific article

Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress.

scientific article published on 26 August 2014

Evidence that the EphA2 receptor exacerbates ischemic brain injury

scientific article

Evidence that γ-Secretase-Mediated Notch Signaling Induces Neuronal Cell Death via the Nuclear Factor-κB-Bcl-2-Interacting Mediator of Cell Death Pathway in Ischemic Stroke

scientific article published on March 30, 2011

FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.

scientific article

Fermented ginseng extract, BST204, disturbs adipogenesis of mesenchymal stem cells through inhibition of S6 kinase 1 signaling

scientific article published on 08 August 2018

Functional recovery in photo-damaged human dermal fibroblasts by human adipose-derived stem cell extracellular vesicles

scientific article published on 20 January 2019

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.

scientific article published on 7 May 2006

Genistein mediates the anti-adipogenic actions of Sophora japonica L. extracts.

scientific article published on 8 February 2011

Genome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver

scientific article published on 01 July 2019

Human adipose stem cell-derived extracellular nanovesicles for treatment of chronic liver fibrosis

scientific article published on 22 January 2020

Hyaluronan nanoparticles bearing γ-secretase inhibitor: in vivo therapeutic effects on rheumatoid arthritis

scientific article published on 07 August 2014

Identification and genetic mapping of the mouse Fkbp9 gene encoding a new member of FK506-binding protein family.

scientific article

In situ diselenide-crosslinked polymeric micelles for ROS-mediated anticancer drug delivery.

scientific article published on 21 June 2016

Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis

scientific journal article

Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain.

scientific article published on 3 January 2015

Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis

scientific article published on 09 September 2018

Intermittent fasting attenuates inflammasome activity in ischemic stroke

scientific article

Intermittent fasting increases adult hippocampal neurogenesis

scientific article published on 05 December 2019

Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke

scientific article published in January 2017

Intracellular and Mitochondrial Reactive Oxygen Species Measurement in Primary Cultured Neurons

publication published on 05 June 2018

Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways

scientific article published on 27 April 2012

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

scientific article published on 05 September 2013

Involvement of notch signaling in wound healing

scientific article

Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis

scientific article published on 01 December 2010

Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo

scientific article published on 05 June 2013

Modelling APOE ɛ3/4 allele-associated sporadic Alzheimer's disease in an induced neuron.

scientific article

Monitoring of early diagnosis of Alzheimer's disease using the cellular prion protein and poly(pyrrole-2-carboxylic acid) modified electrode

scientific article published on 01 May 2018

Morin attenuates tau hyperphosphorylation by inhibiting GSK3β.

scientific article

Mulberry Fruit Extract Ameliorates Nonalcoholic Fatty Liver Disease (NAFLD) through Inhibition of Mitochondrial Oxidative Stress in Rats

scientific article published on 13 December 2018

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models

scientific article published on 04 June 2019

Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin

scientific journal article

Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.

scientific article

Neuroprotective actions of a histidine analogue in models of ischemic stroke

scientific article

Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia.

scientific article published on 7 July 2011

Notch signaling and neuronal death in stroke.

scientific article published on 21 March 2018

Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy

scientific article published on 09 October 2018

Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis

scientific article published on 2 July 2008

O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease

scientific article published on 01 January 2020

OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin

scientific article

Overexpression of calsenilin enhances gamma-secretase activity.

scientific article

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

scientific article

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein

scientific article

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

scientific article published on 7 October 2017

Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death.

scientific article published in February 2007

Phytochemicals in Ischemic Stroke

scientific article published on 18 May 2016

Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain.

scientific article published on 3 February 2015

Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine.

scientific article published on 23 January 2014

Proapoptotic effects of tau cleavage product generated by caspase-3.

scientific article

Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice

scientific journal article

Recent developments in hyaluronic acid-based nanomedicine for targeted cancer treatment.

scientific article

Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients

scientific article (publication date: 3 April 2003)

Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis

scientific article

S6K1 controls epigenetic plasticity for the expression of pancreatic α/β cell marker genes.

scientific article published on 17 April 2018

SERP1 is an assembly regulator of γ-secretase in metabolic stress conditions

scientific article published on 17 March 2020

Secretases as therapeutic targets for Alzheimer's disease.

scientific article published on 03 December 2010

Selenium attenuates A beta production and A beta-induced neuronal death.

scientific article

Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis.

scientific article published in November 2013

Site-specific impairment of perivascular adipose tissue on advanced atherosclerotic plaques using multimodal nonlinear optical imaging

scientific article published on 19 August 2019

Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells

scientific article

TNF-α gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis

scientific article published on 22 October 2013

TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease

scientific article published on 05 September 2018

Therapeutic Approaches to Alzheimer's Disease Through Modulation of NRF2

scientific article published on 07 January 2019

Thiolated Glycol Chitosan Bearing α -Cyclodextrin for Sustained Delivery of PEGylated Human Growth Hormone

scientific article published on May 8, 2012

Transcriptome Analysis Reveals Intermittent Fasting-Induced Genetic Changes in Ischemic Stroke

scientific article published on 13 February 2018

Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.

scientific article

Vanillin attenuates negative effects of ultraviolet A on the stemness of human adipose tissue-derived mesenchymal stem cells.

scientific article published on 25 July 2016

White matter and neurological disorders

scientific article published on 25 September 2020

miR-195a inhibits adipocyte differentiation by targeting the preadipogenic determinator Zfp423.

scientific article published on 21 April 2015