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List of works by Martin Villalba

5' and 3' untranslated regions contribute to the differential expression of specific HLA-A alleles

scientific article published on 13 October 2015

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

scientific article published on February 2000

A possible role for PKCδ in cerebellar granule cells apoptosis

scientific article published on July 13, 1998

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells.

scientific article published on 27 October 2016

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

scientific article published in April 1995

Age-related changes in calcium homeostatic mechanisms in synaptosomes in relation with working memory deficiency.

scientific article published in September 1993

All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity

scientific article published on 15 January 2014

Altered cell calcium regulation in synaptosomes and brain cells of the 30-month-old rat: prominent effects in hippocampus

scientific article published on 01 September 1995

CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity.

scientific article

Chemical metabolic inhibitors for the treatment of blood-borne cancers

scientific article (publication date: February 2014)

Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

scientific article

Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival.

scientific article published on 15 February 2014

Dissecting the NK Cell Population in Hematological Cancers Confirms the Presence of Tumor Cells and Their Impact on NK Population Function

scientific article published on 02 December 2020

Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells.

scientific article

ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

scientific article published on December 2006

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

scientific article

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

scientific article published on 14 June 2018

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells

scientific article

From tumor cell metabolism to tumor immune escape

scientific article published on 05 May 2012

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

scientific article

Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

scientific article published on 26 November 2015

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

scientific article published on 9 January 2015

IFNα signaling through PKC-θ is essential for antitumor NK cell function

scientific article

Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers

scientific article

Impaired anti-leukemic immune response in PKCtheta-deficient mice

scientific article published on 06 May 2008

Insulin-like growth factor-I modulation of cerebellar cell populations is developmentally stage-dependent and mediated by specific intracellular pathways.

scientific article published in March 1998

Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by 13C NMR spectroscopy with multiple 13C labels

scientific article published on December 1, 2001

Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan

scientific article

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

scientific article

Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells

scientific article published on 04 April 2019

Mitochondrial Complex I activity signals antioxidant response through ERK5.

scientific article

Mouse microglial cells express a plasma membrane pore gated by extracellular ATP

scientific article published on 01 February 1996

Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells

scientific article published on 21 July 2019

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

scholarly article

NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment

scientific article published on 20 December 2017

NMDA-induced increase in [Ca2+]i and 45Ca2+ uptake in acutely dissociated brain cells derived from adult rats

scientific article published on January 20, 1992

Non-Genetically Improving the Natural Cytotoxicity of Natural Killer (NK) Cells

scientific article published on 01 January 2019

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

scientific article published on 20 August 2010

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

scientific article published in January 1997

Polyoxidonium® Activates Cytotoxic Lymphocyte Responses Through Dendritic Cell Maturation: Clinical Effects in Breast Cancer

scientific article published on 28 November 2019

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

scientific article

Prolactin increases cytosolic free calcium concentration in hepatocytes of lactating rats

scientific article published on 01 December 1991

Protection by pyruvate and malate against glutamate-mediated neurotoxicity.

scientific article published in May 1998

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity

scientific article published on July 5, 2012

Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias.

scientific article

Protein kinase C-theta (PKCtheta): it's all about location, location, location.

scientific article

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

scientific article published in February 2009

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

scientific article

Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death

scientific article published on 01 December 1999

SUMOylation regulates the transcriptional activity of JunB in T lymphocytes.

scientific article published in May 2008

The NF-κB member p65 controls glutamine metabolism through miR-23a.

scientific article

The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

scientific article published on 6 September 2017

The activity of synaptosomal calcium channels is inversely correlated with working memory performance in memory impaired, aged rats.

scientific article published in January 1994

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

scientific article

The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis.

scientific article

The role of ERK5 in T-cell signalling.

scientific article published in December 2005

The role of pyruvate in neuronal calcium homeostasis. Effects on intracellular calcium pools.

scientific article published on January 1994

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

scientific article

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

scientific article published on 01 June 2000

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

scientific article published on October 29, 2001

What came first: PKCtheta or the immune synapse?

scientific article published on January 2004

miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice

scientific article