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List of works by David Pamies

21st Century Cell Culture for 21st Century Toxicology

scientific article published on 5 December 2016

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

scientific article published in Scientific Reports

A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis.

scientific article published on 08 December 2015

A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity

scientific article published on 24 November 2016

A human pluripotent carcinoma stem cell‐based model for in vitro developmental neurotoxicity testing: Effects of methylmercury, lead and aluminum evaluated by gene expression studies

scientific article published on March 13, 2013

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

scientific article published on 13 April 2018

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities

scientific article published on 04 May 2016

An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE).

scientific article

An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods.

scientific article published on 03 February 2014

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

scientific article published on 21 February 2020

Biological and medical applications of a brain-on-a-chip

scientific article (publication date: September 2014)

Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis

scientific article published in October 2016

Consensus report on the future of animal-free systemic toxicity testing

scientific article

Explosive Blast Loading on Human 3D Aggregate Minibrains

scientific article published on 21 January 2017

Expression of Neuropathy Target Esterase in mouse embryonic stem cells during differentiation.

scientific article

Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation.

scientific article published on 19 October 2013

Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

scientific article published on 09 January 2014

Good Cell Culture Practice for stem cells and stem-cell-derived models.

scientific article published on 23 August 2016

Good cell culture practices &in vitro toxicology.

scientific article published on 24 April 2017

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

scientific article published on 09 July 2019

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

article

Necrotizing enterocolitis induces T lymphocyte-mediated injury in the developing mammalian brain

scientific article published on 01 January 2021

Organophosphorus pesticide chlorpyrifos and its metabolites alter the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells in a comparable way to other model neurodevelopmental toxicants

scientific article published on 29 August 2014

Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem

scientific article published on 01 October 2020

Quality assurance of metabolomics.

scientific article published on January 2015

Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity

scientific article

Rotenone exerts developmental neurotoxicity in a human brain spheroid model.

scientific article published on 8 February 2018

Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2).

scientific article

Specific effect of 5-fluorouracil on alpha-fetoprotein gene expression during the in vitro mouse embryonic stem cell differentiation

scientific article

Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery.

scientific article published on 3 June 2019

Supporting read-across using biological data

scientific article (publication date: 2016)

Toward Good Read-Across Practice (GRAP) guidance

scientific article

Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone

scientific article published on 28 June 2018

miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing

scientific article published on August 1, 2013