List of works - Sankar Surendran

Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease

scientific article published in May 2003

Altered expression of myocilin in the brain of a mouse model for phenylketonuria (PKU).

scientific article published on 2 April 2005

Altered expression of neuronal nitric oxide synthase in the duodenum longitudinal muscle-myenteric plexus of obesity induced diabetes mouse: implications on enteric neurodegeneration.

scientific article published on 21 October 2005

Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease.

scientific article published on 26 February 2009

Aspartoacylase Deficiency in the White Matter of Human Immunodeficiency Virus Encephalitis: Novel Mechanism in Axonal Damage ⬇️

scientific article published on September 6, 2011

Aspartoacylase gene knockout in the mouse: impact on reproduction

scientific article published on 01 July 2005

Aspartoacylase gene knockout results in severe vacuolation in the white matter and gray matter of the spinal cord in the mouse

scientific article published in March 2005

Biopterin responsive phenylalanine hydroxylase deficiency

scientific article

Canavan disease: a monogenic trait with complex genomic interaction.

scientific article published on September 2003

Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations

scholarly article

DOOR syndrome: deficiency of E1 component of the 2-oxoglutarate dehydrogenase complex.

scientific article published in December 2002

Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease.

scientific article

Expression of calpastatin, minopontin, NIPSNAP1, rabaptin-5 and neuronatin in the phenylketonuria (PKU) mouse brain: possible role on cognitive defect seen in PKU.

scientific article

Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease

scientific article published in August 2003

Fas (CD95) alters neuronal nitric oxide synthase expression to contribute in diabetic gastroparesis

scientific article published on 11 December 2006

Founder mutation R245H of Sanfilippo syndrome type A in the Cayman Islands

scientific article published on 01 January 2002

High level of orexin A observed in the phenylketonuria mouse brain is due to the abnormal expression of prepro-orexin.

scientific article published in April 2004

High levels of orexin A in the brain of the mouse model for phenylketonuria: possible role of orexin A in hyperactivity seen in children with PKU.

scientific article

Hyaluronidase increases the biodistribution of acid alpha-1,4 glucosidase in the muscle of Pompe disease mice: an approach to enhance the efficacy of enzyme replacement therapy

scientific article published on 2 October 2006

Malonyl CoA decarboxylase deficiency: C to T transition in intron 2 of the MCD gene.

scientific article

Mental retardation and hypotonia seen in the knock out mouse for Canavan disease is not due to succinate semialdehyde dehydrogenase deficiency.

scientific article published in March 2004

Mouse neural progenitor cells differentiate into oligodendrocytes in the brain of a knockout mouse model of Canavan disease

scientific article published on 01 October 2004

Mutations in the Regulatory Domain of Phenylalanine Hydroxylase and Response to Tetrahydrobiopterin

article

Parkinson's disease: oxidative stress and therapeutic approaches.

scientific article published on 10 March 2010

Possible role of fas antigen (CD 95) in human amniotic epithelial cell death: an in vitro study

scientific article published on 01 January 2001

Soluble factors from IL-1β-stimulated astrocytes activate NR1a/NR2B receptors: implications for HIV-1-induced neurodegeneration.

scientific article

Trends in enzyme therapy for phenylketonuria.

scientific article published in August 2004

Upregulation of N-acetylaspartic acid alters inflammation, transcription and contractile associated protein levels in the stomach and smooth muscle contractility.

scientific article published on 18 October 2007

Upregulation of N-acetylaspartic acid induces oxidative stress to contribute in disease pathophysiology.

scientific article published on 25 February 2011

Upregulation of N-acetylaspartic acid resulting nitric oxide toxicity induces aspartoacylase mutations and protein interaction to cause pathophysiology seen in Canavan disease ⬇️

scientific article published on July 31, 2010

Upregulation of aspartoacylase seen in diabetes is due to advanced glycation end-products

scientific article published on 14 November 2006

Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse.

scientific article published on 8 August 2009

List of works by Sankar Surendran

Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease

Altered expression of myocilin in the brain of a mouse model for phenylketonuria (PKU).

Altered expression of neuronal nitric oxide synthase in the duodenum longitudinal muscle-myenteric plexus of obesity induced diabetes mouse: implications on enteric neurodegeneration.

Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease.

Aspartoacylase Deficiency in the White Matter of Human Immunodeficiency Virus Encephalitis: Novel Mechanism in Axonal Damage ⬇️

Aspartoacylase gene knockout in the mouse: impact on reproduction

Aspartoacylase gene knockout results in severe vacuolation in the white matter and gray matter of the spinal cord in the mouse

Biopterin responsive phenylalanine hydroxylase deficiency

Canavan disease: a monogenic trait with complex genomic interaction.

Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations

DOOR syndrome: deficiency of E1 component of the 2-oxoglutarate dehydrogenase complex.

Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease.

Expression of calpastatin, minopontin, NIPSNAP1, rabaptin-5 and neuronatin in the phenylketonuria (PKU) mouse brain: possible role on cognitive defect seen in PKU.

Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease

Fas (CD95) alters neuronal nitric oxide synthase expression to contribute in diabetic gastroparesis

Founder mutation R245H of Sanfilippo syndrome type A in the Cayman Islands

High level of orexin A observed in the phenylketonuria mouse brain is due to the abnormal expression of prepro-orexin.

High levels of orexin A in the brain of the mouse model for phenylketonuria: possible role of orexin A in hyperactivity seen in children with PKU.

Hyaluronidase increases the biodistribution of acid alpha-1,4 glucosidase in the muscle of Pompe disease mice: an approach to enhance the efficacy of enzyme replacement therapy

Malonyl CoA decarboxylase deficiency: C to T transition in intron 2 of the MCD gene.

Mental retardation and hypotonia seen in the knock out mouse for Canavan disease is not due to succinate semialdehyde dehydrogenase deficiency.

Mouse neural progenitor cells differentiate into oligodendrocytes in the brain of a knockout mouse model of Canavan disease

Mutations in the Regulatory Domain of Phenylalanine Hydroxylase and Response to Tetrahydrobiopterin

Parkinson's disease: oxidative stress and therapeutic approaches.

Possible role of fas antigen (CD 95) in human amniotic epithelial cell death: an in vitro study

Soluble factors from IL-1β-stimulated astrocytes activate NR1a/NR2B receptors: implications for HIV-1-induced neurodegeneration.

Trends in enzyme therapy for phenylketonuria.

Upregulation of N-acetylaspartic acid alters inflammation, transcription and contractile associated protein levels in the stomach and smooth muscle contractility.

Upregulation of N-acetylaspartic acid induces oxidative stress to contribute in disease pathophysiology.

Upregulation of N-acetylaspartic acid resulting nitric oxide toxicity induces aspartoacylase mutations and protein interaction to cause pathophysiology seen in Canavan disease ⬇️

Upregulation of aspartoacylase seen in diabetes is due to advanced glycation end-products

Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse.