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List of works by Matthew Williams

A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma

scientific article published on 06 July 2016

Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.

scientific article

Bim mediates the elimination of functionally unfit Th1 responders from the memory pool.

scientific article

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

scientific article

Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance.

scientific article published in November 2001

Conventional Immunosuppression is Compatible with Costimulation Blockade-Based, Mixed Chimerism Tolerance Induction

scientific article published on 01 July 2003

Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression.

scientific article

Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control Following CD28/CD40 Blockade-Based Regimen

scientific article published on 01 November 2002

Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation.

scientific article published on August 2005

Developing and maintaining protective CD8+ memory T cells.

scientific article published on June 2006

Disparate roles for STAT5 in primary and secondary CTL responses.

scientific article published on 25 February 2013

Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ effector and memory T cells.

scientific article published on 14 May 2010

Dynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus

scientific article

Exhausted T cells perk up

scientific article published in Nature

Fully MHC-Disparate Mixed Hemopoietic Chimeras Show Specific Defects in the Control of Chronic Viral Infections

scientific article published on 01 August 2007

Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts.

scientific article published in December 2000

IFN-Gamma-Dependent and Independent Mechanisms of CD4⁺ Memory T Cell-Mediated Protection from Listeria Infection

scientific article published on 13 February 2018

IL-10 Deficiency Reveals a Role for TLR2-Dependent Bystander Activation of T Cells in Lyme Arthritis.

scientific article published on 12 January 2018

Inhibition of RON kinase potentiates anti-CTLA-4 immunotherapy to shrink breast tumors and prevent metastatic outgrowth

scientific article published on 11 July 2018

Inhibition of SHP-1 Expands the Repertoire of Antitumor T Cells Available to Respond to Immune Checkpoint Blockade

scientific article published on 19 February 2020

Instant recall: a key role for effector-phenotype CD8⁺ memory T cells in immune protection.

scientific article published on June 2013

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

scientific article published on June 2006

Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool.

scientific article published on 25 August 2010

Oct1 and OCA-B are selectively required for CD4 memory T cell function

scientific article

Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.

scientific article

Prevention of chronic rejection in murine cardiac allografts: a comparison of chimerism- and nonchimerism-inducing costimulation blockade-based tolerance induction regimens.

scientific article published in September 2002

Primary and secondary immunocompetence in mixed allogeneic chimeras.

scientific article published in March 2003

Stability and function of secondary Th1 memory cells are dependent on the nature of the secondary stimulus.

scientific article

Sustained interactions between T cell receptors and antigens promote the differentiation of CD4⁺ memory T cells.

scientific article published on September 2013

T cell memory: fixed or flexible?

scientific article published in August 2005

TCR signal strength controls the differentiation of CD4 effector and memory T cells

scientific article published on 01 July 2018

miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation

scientific article published on October 2014

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