List of works - Chandralal Hewage

13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line.

scientific article published on 4 September 2003

13C and1H NMR Studies of Ionizations and Hydrogen Bonding in Chymotrypsin-Glyoxal Inhibitor Complexes

scientific article published in Journal of Biological Chemistry

13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor

scientific article published on March 2002

1H NMR spectroscopy as a tool to evaluate key metabolic functions of primary porcine hepatocytes after cryopreservation

scientific article published in May 2002

4-hydroxyphenylacetic acid derivatives of inositol from dandelion (Taraxacum officinale) root characterised using LC-SPE-NMR and LC-MS techniques.

scientific article

A 13C-NMR study of azacryptand complexes

scientific article published on 01 September 2014

A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

scientific article published in September 2002

A linear endothelin-1 analogue: solution structure of ET-1[Aib1,3,11,15, Nle7] by nuclear magnetic resonance spectroscopy and molecular modelling.

scientific article

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secreti

scientific article

An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids

scientific article

Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit

article

Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6.

scientific article

Characterisation of Antimicrobial Extracts from Dandelion Root ( Taraxacum officinale ) Using LC-SPE-NMR

scientific article (publication date: 21 January 2015)

Comparison of bioenergetic activity of primary porcine hepatocytes cultured in four different media.

scientific article

Conformational analysis of the broad-spectrum antibacterial peptide, ranatuerin-2CSa: identification of a full length helix-turn-helix motif

scientific article

Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain

scientific article

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide

scientific article

Design of ET(B) receptor agonists: NMR spectroscopic and conformational studies of ET7-21[Leu7, Aib11, Cys(Acm)15].

scientific article

Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors.

scientific article

Development of ET(B) selective agonists: solution structure of a linear endothelin-1 analogue, ET-1 [Cys(Acm)(1,15), Ala3, Leu7, dAsp8, Aib11].

scientific article published in October 1998

Development of potent anti-infective agents from Silurana tropicalis: Conformational analysis of the amphipathic, alpha-helical antimicrobial peptide XT-7 and its non-haemolytic analogue [G4K]XT-7

article

Generation and contrasting gas-phase reactivity of 2-(2-alkenylpyrrol-1-yl)phenoxyl and thiophenoxyl radicals

scientific article published on 18 May 2006

Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.

scientific article published on December 2004

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.

scientific article published on 20 April 2016

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

scientific article published on 8 January 2010

Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes

scientific article published on 2 February 2006

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens

scientific article published on 22 February 2011

Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides

scientific article published on 12 September 2019

Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts.

scientific article published on 4 April 2014

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism

scientific article published on 20 October 2006

Ionisations within a subtilisin-glyoxal inhibitor complex

scientific article published in May 2005

Metabolic and structural properties of human obestatin {1-23} and two fragment peptides

scientific article

Methyl ester of para-coumaric acid: antifungal principle of the rhizome of Costus speciosus

scientific article published on 01 October 1988

Modification of chicken avian beta-defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity.

scientific article published on 5 May 2007

N alpha- and N epsilon-D-galacturonoyl-L-lysine amides: properties and possible occurrence in plant cell walls.

scientific article

NMR Study of the Inhibition of Pepsin by Glyoxal Inhibitors: Mechanism of Tetrahedral Intermediate Stabilization by the Aspartyl Proteases†

scientific article published on 07 September 2007

NMR model structure of the antimicrobial peptide maximin 3

scientific article published on 08 February 2019

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1–30)amide

scientific article published on 01 December 2004

Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct.

scientific article published on 21 April 2009

Patterns of methyl and O-acetyl esterification in spinach pectins: new complexity.

scientific article published in May 2002

Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

scientific article published on February 2009

Racemisation of N-Fmoc phenylglycine under mild microwave-SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this

scientific article published on 26 March 2012

Remeasuring HEWL pK(a) values by NMR spectroscopy: methods, analysis, accuracy, and implications for theoretical pK(a) calculations

scientific article

Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling

scientific article

Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments

scientific article published on 01 November 2019

Structural aspects of gut peptides with therapeutic potential for type 2 diabetes.

scientific article published on 04 January 2013

List of works by Chandralal Hewage

13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line.

13C and1H NMR Studies of Ionizations and Hydrogen Bonding in Chymotrypsin-Glyoxal Inhibitor Complexes

13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor

1H NMR spectroscopy as a tool to evaluate key metabolic functions of primary porcine hepatocytes after cryopreservation

4-hydroxyphenylacetic acid derivatives of inositol from dandelion (Taraxacum officinale) root characterised using LC-SPE-NMR and LC-MS techniques.

A 13C-NMR study of azacryptand complexes

A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

A linear endothelin-1 analogue: solution structure of ET-1[Aib1,3,11,15, Nle7] by nuclear magnetic resonance spectroscopy and molecular modelling.

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secreti

An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids

Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit

Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6.

Characterisation of Antimicrobial Extracts from Dandelion Root ( Taraxacum officinale ) Using LC-SPE-NMR

Comparison of bioenergetic activity of primary porcine hepatocytes cultured in four different media.

Conformational analysis of the broad-spectrum antibacterial peptide, ranatuerin-2CSa: identification of a full length helix-turn-helix motif

Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide

Design of ET(B) receptor agonists: NMR spectroscopic and conformational studies of ET7-21[Leu7, Aib11, Cys(Acm)15].

Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors.

Development of ET(B) selective agonists: solution structure of a linear endothelin-1 analogue, ET-1 [Cys(Acm)(1,15), Ala3, Leu7, dAsp8, Aib11].

Development of potent anti-infective agents from Silurana tropicalis: Conformational analysis of the amphipathic, alpha-helical antimicrobial peptide XT-7 and its non-haemolytic analogue [G4K]XT-7

Generation and contrasting gas-phase reactivity of 2-(2-alkenylpyrrol-1-yl)phenoxyl and thiophenoxyl radicals

Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens

Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides

Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts.

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism

Ionisations within a subtilisin-glyoxal inhibitor complex

Metabolic and structural properties of human obestatin {1-23} and two fragment peptides

Methyl ester of para-coumaric acid: antifungal principle of the rhizome of Costus speciosus

Modification of chicken avian beta-defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity.

N alpha- and N epsilon-D-galacturonoyl-L-lysine amides: properties and possible occurrence in plant cell walls.

NMR Study of the Inhibition of Pepsin by Glyoxal Inhibitors: Mechanism of Tetrahedral Intermediate Stabilization by the Aspartyl Proteases†

NMR model structure of the antimicrobial peptide maximin 3

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1–30)amide

Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct.

Patterns of methyl and O-acetyl esterification in spinach pectins: new complexity.

Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

Racemisation of N-Fmoc phenylglycine under mild microwave-SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this

Remeasuring HEWL pK(a) values by NMR spectroscopy: methods, analysis, accuracy, and implications for theoretical pK(a) calculations

Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling

Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments

Structural aspects of gut peptides with therapeutic potential for type 2 diabetes.