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List of works by James A Nathan

A thermostable, closed SARS-CoV-2 spike protein trimer

scientific article published on 31 July 2020

A thermostable, closed, SARS-CoV-2 spike protein trimer

preprint published on 17 June 2020

ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex

scientific article published on 13 August 2020

APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS

scientific article published on 01 January 2019

Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins

scientific article

Different opinion on the reported role of Poldip2 and ACSM1 in a mammalian lipoic acid salvage pathway controlling HIF-1 activation

scientific article published on 24 July 2018

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

scientific article published on 28 March 2017

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

scientific journal article

Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins

scientific article published on February 2013

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

scientific article

Metabolic Regulation of Hypoxia-Inducible Transcription Factors: The Role of Small Molecule Metabolites and Iron

scientific article published on 17 May 2018

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry

scientific article

Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.

scientific article published on 27 October 2016

Muscle wasting in disease: molecular mechanisms and promising therapies

scientific article published on January 2015

Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria

scientific article published on 31 January 2018

Skeletal muscle dysfunction: a ubiquitous outcome in chronic disease?

scientific article published on 01 February 2010

Squalene and cholesterol in the balance at the ER membrane

scientific article published on 01 April 2020

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

scientific article published on 12 May 2010

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

scientific article

The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome.

scientific article published on 21 August 2013

The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains

scientific article

The recognition of ubiquitinated proteins by the proteasome

scientific article

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

scientific article published on 13 December 2018

The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases.

scientific article

The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X

scientific article published on 11 April 2008

The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels

scientific article

The value of performing head CT in screening for cerebral metastases in patients with potentially resectable non-small cell lung cancer: experience from a UK cardiothoracic centre

scientific article published on 01 October 2004

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

scientific article published on January 11, 2013