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List of works by Pablo Perez-Pinera

APP processing and the APP-KPI domain involvement in the amyloid cascade.

scientific article

Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine

scientific article

Advances in targeted genome editing

scientific article published on 20 July 2012

Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation

scientific article

Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer.

scientific article

Biomedical applications of gene editing.

scientific article

CRISPR-SKIP: programmable gene splicing with single base editors

article

Characterization of sensory deficits in TrkB knockout mice.

scientific article published on 14 January 2008

Clinical implication of Meissner`s corpuscles

scientific article

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases

scientific article

Damage, Healing, and Remodeling in Optogenetic Skeletal Muscle Bioactuators

scientific article published on 10 May 2017

Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum.

scientific article published on 21 September 2016

Development and neuronal dependence of cutaneous sensory nerve formations: Lessons from neurotrophins

scientific article published on May 2010

Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles

scientific article

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

scientific article published on 01 September 2018

Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology.

scientific article

Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development.

scientific article

Expression and cell localization of brain-derived neurotrophic factor and TrkB during zebrafish retinal development.

scientific article

Fyn is a downstream target of the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta-signaling pathway: regulation of tyrosine phosphorylation of Fyn by pleiotrophin

scientific article published in July 2005

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

scientific article

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

scientific article published on 29 May 2015

Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins

scientific article published on 10 September 2010

Hypertonicity activates GSK3beta in tumor cells

scientific article published on 10 June 2006

Identification of the angiogenesis signaling domain in pleiotrophin defines a mechanism of the angiogenic switch

scientific article published on 10 March 2006

Immunohistochemical profile of human pancreatic pacinian corpuscles.

scientific article published in April 2010

Immunotherapy for Alzheimer's disease: rational basis in ongoing clinical trials.

scientific article published on January 2011

In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA.

scientific article published on 11 February 2016

Mammalian Synthetic Biology: Engineering Biological Systems.

scientific article

Multiplexed Targeted Genome Engineering Using a Universal Nuclease-Assisted Vector Integration System

scientific article

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

scientific article

Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration

scientific article published on 01 July 2019

Plasmatic level of neurosin predicts outcome of mild cognitive impairment.

scientific article published on 11 July 2008

Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition

scholarly article

Pleiotrophin expression during odontogenesis

scientific article

Pleiotrophin inhibits hippocampal long-term potentiation: a role of pleiotrophin in learning and memory.

scientific article published in June 2009

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.

scientific article published on 5 December 2008

Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C

scientific article published on 22 August 2005

Pleiotrophin stimulates tyrosine phosphorylation of beta-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase beta/zeta.

scientific article published on September 2005

Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis.

scientific article published on May 2008

Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts.

scientific article published on December 2007

Production of Functional Anti-Ebola Antibodies in Pichia pastoris.

scientific article

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

scientific article

Putting Non-coding RNA on Display with CRISPR.

scientific article

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

scientific article

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

scientific article published on 04 June 2013

S-100 proteins in the human peripheral nervous system

scientific article

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.

scientific article published on 18 February 2014

Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment.

scholarly article

Sodium chloride regulates Extracellular Regulated Kinase 1/2 in different tumor cell lines

scientific article published on 21 September 2006

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

scientific article published on 3 February 2013

Synthetic biology and microbioreactor platforms for programmable production of biologics at the point-of-care

scientific article

Targeted Gene Activation Using RNA-Guided Nucleases

scientific article published on January 2017

Targeted Gene Knock Out Using Nuclease-Assisted Vector Integration: Hemi- and Homozygous Deletion of JAG1

scientific article published on 01 January 2018

The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

scientific article published on 22 July 2006

The continuously evolving CRISPR barcoding toolbox

scientific article published on 25 September 2018

The expression of ENa(+)C and ASIC2 proteins in Pacinian corpuscles is differently regulated by TrkB and its ligands BDNF and NT-4.

scientific article published on 29 July 2009

The lamellar cells in human Meissner corpuscles express TrkB

scientific article published on 29 October 2009

The neurotrophic factor pleiotrophin modulates amphetamine-seeking behaviour and amphetamine-induced neurotoxic effects: evidence from pleiotrophin knockout mice

scientific article published in October 2010

The receptor protein tyrosine phosphatase (RPTP)beta/zeta is expressed in different subtypes of human breast cancer

scientific article

Thymocyte depletion affects neurotrophin receptor expression in thymic stromal cells

scientific article published on 01 February 2006

TrkB is necessary for the normal development of the lung.

scientific article

Value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer's disease

scientific article

Versatile and on-demand biologics co-production in yeast.

scientific article published on 8 January 2018

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