List of works - Sergey Kozin

A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

scientific article

Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

scientific article published on 15 May 2017

Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation.

scientific article published on 23 February 2018

Application of MALDI-TOF/TOF-MS for relative quantitation of α- and β-Asp7 isoforms of amyloid-β peptide.

scientific article published in January 2017

Capabilities of MS for Analytical Quantitative Determination of the Ratio of α- and βAsp7 Isoforms of the Amyloid-β Peptide in Binary Mixtures

scientific article published on 16 March 2011

Chemical modifications of amyloid-β(1-42) have a significant impact on the repertoire of brain amyloid-β(1-42) binding proteins.

scientific article published on 8 July 2016

Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice.

scientific article

Effect of mutations and modifications of amino acid residues on zinc-induced interaction of the metal-binding domain of β-amyloid with DNA

scientific article

HSP70 protects human neuroblastoma cells from apoptosis and oxidative stress induced by amyloid peptide isoAsp7-Aβ(1-42).

scientific article published on 19 November 2015

Heparin Modulates the Kinetics of Zinc-Induced Aggregation of Amyloid-β Peptides

scientific article published on 3 April 2018

Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization

scientific article

Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice

scientific article published on 3 February 2016

Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer's Disease

scholarly article by Sergey Kozin et al published 2018 in Frontiers in Neuroscience

Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells

scientific article published on 28 November 2013

Minimal Zn(2+) binding site of amyloid-β.

scientific article published on November 2010

N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-β(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease

scientific article published on 10 January 2018

NMR solution structure of rat aβ(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease

scientific article

New biomarkers and drug targets for diagnosis and therapy of Alzheimer’s disease (molecular determinants of zinc-dependent oligomerization of β-amyloid)

scientific article published on 01 January 2015

Peripherally Applied Synthetic Peptide isoAsp7-Aβ(1-42) Triggers Cerebral β-Amyloidosis ⬇️

scientific article published on May 14, 2013

Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.

scientific article published in June 2015

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition

scholarly article by Evgeny P Barykin published in January 2018

Physico-chemical methods for studing β-amyloid aggregation

scientific article published in March 2015

Possible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein.

scientific article published on 10 November 2004

Protein interactomics based on direct molecular fishing on paramagnetic particles: Practical realization and further SPR validation

scientific article published on 21 August 2014

Secondary Structure of Aβ(1-16) Complexes with Zinc: A Study in the Gas Phase Using Deuterium/Hydrogen Exchange and Ultra-High-Resolution Mass Spectrometry

scientific article published in July 2017

Sheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solution

scientific article

Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging

scientific article published on 21 November 2005

Supermetallization of peptides and proteins during electrospray ionization

scientific article published in September 2015

The English (H6R) familial Alzheimer's disease mutation facilitates zinc-induced dimerization of the amyloid-β metal-binding domain

scientific article published in March 2015

The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser [...]

scientific article

The effects of endogenous non-peptide molecule isatin and hydrogen peroxide on proteomic profiling of rat brain amyloid-β binding proteins: relevance to Alzheimer's disease?

scientific article published on 29 December 2014

Zinc Binding to Alzheimer's Aβ(1–16) Peptide Results in Stable Soluble Complex

scientific article published on 01 July 2001

Zinc binding agonist effect on the recognition of the beta-amyloid (4-10) epitope by anti-beta-amyloid antibodies

scientific article

Zinc-Induced Interaction of the Metal-Binding Domain of Amyloid-β Peptide with DNA ⬇️

scientific article published on January 1, 2013

Zinc-Mediated Binding of Nucleic Acids to Amyloid-β Aggregates: Role of Histidine Residues

scientific article published on 01 September 2016

Zinc-induced heterodimer formation between metal-binding domains of intact and naturally modified amyloid-beta species: implication to amyloid seeding in Alzheimer's disease?

scientific article published on 29 October 2015

Zinc-induced interactions of the metal-binding domain of beta-amyloid with nucleic acids and glycosaminoglycans

scientific article

Эналаприлат ингибирует цинкзависимую олигомеризацию металлсвязывающего домена изоформ бета-амилоида и защищает клетки нейробластомы

scientific article published on 01 July 2018

List of works by Sergey Kozin

A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-β Fragment with Taiwanese Mutation D7H.

Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation.

Application of MALDI-TOF/TOF-MS for relative quantitation of α- and β-Asp7 isoforms of amyloid-β peptide.

Capabilities of MS for Analytical Quantitative Determination of the Ratio of α- and βAsp7 Isoforms of the Amyloid-β Peptide in Binary Mixtures

Chemical modifications of amyloid-β(1-42) have a significant impact on the repertoire of brain amyloid-β(1-42) binding proteins.

Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice.

Effect of mutations and modifications of amino acid residues on zinc-induced interaction of the metal-binding domain of β-amyloid with DNA

HSP70 protects human neuroblastoma cells from apoptosis and oxidative stress induced by amyloid peptide isoAsp7-Aβ(1-42).

Heparin Modulates the Kinetics of Zinc-Induced Aggregation of Amyloid-β Peptides

Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization

Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice

Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer's Disease

Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells

Minimal Zn(2+) binding site of amyloid-β.

N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-β(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease

NMR solution structure of rat aβ(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease

New biomarkers and drug targets for diagnosis and therapy of Alzheimer’s disease (molecular determinants of zinc-dependent oligomerization of β-amyloid)

Peripherally Applied Synthetic Peptide isoAsp7-Aβ(1-42) Triggers Cerebral β-Amyloidosis ⬇️

Peripherally Applied Synthetic Tetrapeptides HAEE and RADD Slow Down the Development of Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice.

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition

Physico-chemical methods for studing β-amyloid aggregation

Possible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein.

Protein interactomics based on direct molecular fishing on paramagnetic particles: Practical realization and further SPR validation

Secondary Structure of Aβ(1-16) Complexes with Zinc: A Study in the Gas Phase Using Deuterium/Hydrogen Exchange and Ultra-High-Resolution Mass Spectrometry

Sheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solution

Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging

Supermetallization of peptides and proteins during electrospray ionization

The English (H6R) familial Alzheimer's disease mutation facilitates zinc-induced dimerization of the amyloid-β metal-binding domain

The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser [...]

The effects of endogenous non-peptide molecule isatin and hydrogen peroxide on proteomic profiling of rat brain amyloid-β binding proteins: relevance to Alzheimer's disease?

Zinc Binding to Alzheimer's Aβ(1–16) Peptide Results in Stable Soluble Complex

Zinc binding agonist effect on the recognition of the beta-amyloid (4-10) epitope by anti-beta-amyloid antibodies

Zinc-Induced Interaction of the Metal-Binding Domain of Amyloid-β Peptide with DNA ⬇️

Zinc-Mediated Binding of Nucleic Acids to Amyloid-β Aggregates: Role of Histidine Residues

Zinc-induced heterodimer formation between metal-binding domains of intact and naturally modified amyloid-beta species: implication to amyloid seeding in Alzheimer's disease?

Zinc-induced interactions of the metal-binding domain of beta-amyloid with nucleic acids and glycosaminoglycans

Эналаприлат ингибирует цинкзависимую олигомеризацию металлсвязывающего домена изоформ бета-амилоида и защищает клетки нейробластомы