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List of works by Luca Orlando

A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells.

scientific article published on 14 October 2010

A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia.

scientific article published in June 2008

Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts.

scientific article

An in vitro model of T cell receptor revision in mature human CD8+ T cells.

scientific article

Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media.

scientific article published on 19 June 2015

Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells

scientific article

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes

scientific article published on 13 August 2010

Fluorescent silica nanoparticles improve optical imaging of stem cells allowing direct discrimination between live and early-stage apoptotic cells.

scientific article

High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells

scientific article

Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: a genotype-phenotype correlation study

scientific article

Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease

scientific article published on 28 January 2013

TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells.

scientific article published on 8 April 2011

The cyclin-dependent kinase inhibitor 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic, DNA replication-independent apoptosis of normal and leukemic cells, regardless of their p53 status

scientific article

Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes

scientific article published on 23 January 2009

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