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List of works by Susana Gonzalo

A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin.

scientific article published in February 2018

A dual role for A-type lamins in DNA double-strand break repair

scientific article (publication date: August 2011)

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

scientific article

A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair ⬇️

scientific article published on July 12, 2011

A role for the Rb family of proteins in controlling telomere length

scientific article published on 15 October 2002

BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells ⬇️

scientific article published on January 21, 2013

Calcitriol Prevents RAD51 Loss and cGAS-STING-IFN Response Triggered by Progerin

scientific article published on 30 December 2019

Causes and consequences of genomic instability in laminopathies: replication stress and interferon response

scientific article published on 11 April 2018

Crosstalk between chromatin structure, nuclear compartmentalization, and telomere biology.

scientific article published on January 2008

DNA damage and lamins

scientific article

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.

scientific article

Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells

scientific article published on 2 October 2013

Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet

scientific article published on 12 December 2018

Erratum: A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

scholarly article published in Nature Structural & Molecular Biology

Genomic instability and innate immune responses to self-DNA in progeria

scientific article published on 01 June 2019

Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.

scientific article

Hutchinson-Gilford Progeria Syndrome: Challenges at Bench and Bedside

scientific article published on 01 January 2019

Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability.

scientific article published on September 2013

Linking the Rb and polycomb pathways

scientific article (publication date: September 2001)

Loss of lamin A function increases chromatin dynamics in the nuclear interior.

scientific article published on 24 August 2015

Mechanisms of oncogene-induced genomic instability.

scientific article published on 24 November 2016

Metabolic Dysfunction in Hutchinson-Gilford Progeria Syndrome

scientific article published on 08 February 2020

Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina

scientific article published in January 2016

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway.

scientific article

Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment

scientific article published on 27 September 2013

Nurturing the genome: A-type lamins preserve genomic stability ⬇️

scientific article published on November 29, 2009

Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing

scientific article published on 01 February 2019

Regulating the levels of key factors in cell cycle and DNA repair: new pathways revealed by lamins.

scientific article

Role of Rb family in the epigenetic definition of chromatin.

scientific article published on 8 June 2005

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

scientific article

SNAP-25 Palmitoylation and Plasma Membrane Targeting Require a Functional Secretory Pathway ⬇️

scientific article published on March 1, 1998

SNAP-25 is targeted to the plasma membrane through a novel membrane-binding domain.

scientific article published on July 1999

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

scientific article

Telomere recombination requires the MUS81 endonuclease.

scientific article published on 12 April 2009

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

scientific article

The nuclear lamina in health and disease.

scientific article published on 9 May 2016

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest

scientific article

The two faces of DNA repair: disease and therapy.

scientific article published on July 2013

Tying up loose ends: telomeres, genomic instability and lamins.

scientific article published on 21 March 2016

Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes

scientific article published on 27 April 2016

Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence.

scientific article published on 04 April 2016

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