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List of works by J. Ignacio Casal

A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites.

scientific article

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

scientific article published on 29 October 2016

A novel recombinant virus-like particle vaccine for prevention of porcine parvovirus-induced reproductive failure.

scientific article published on 18 April 2006

A p120-catenin-CK1epsilon complex regulates Wnt signaling.

scientific article published on August 2010

A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and interleukin 17 (IL-17) to inhibit adipocyte differentiation.

scientific article published on 10 December 2014

A proteomics analysis of cell signaling alterations in colorectal cancer

scientific article published on 11 September 2007

A recombinant virus-like particle system derived from parvovirus as an efficient antigen carrier to elicit a polarized Th1 immune response without adjuvant ⬇️

scientific article published on April 1, 1998

Affinity maturation of antibodies assisted by in silico modeling.

scientific article

An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer

scientific article published on 15 October 2018

An RGD motif present in cadherin 17 induces integrin activation and tumor growth

scientific article

An efficient expression system for the production of functionally active human LKB1.

scientific article published in January 2005

Antigenic profile of African horse sickness virus serotype 4 VP5 and identification of a neutralizing epitope shared with bluetongue virus and epizootic hemorrhagic disease virus.

scientific article published on May 1999

Antigenic properties and diagnostic potential of baculovirus-expressed infectious bursal disease virus proteins VPX and VP3.

scientific article published on July 2000

Avian and mammalian reoviruses use different molecular mechanisms to synthesize their {micro}NS isoforms.

scientific article published on 27 July 2011

Baculovirus expression of proteins of porcine reproductive and respiratory syndrome virus strain Olot/91. Involvement of ORF3 and ORF5 proteins in protection.

scientific article published on January 1997

Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.

scientific article published in November 2010

CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules.

scientific article

Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis.

scientific article published on 22 April 2013

Cohesin organizes chromatin loops at DNA replication factories.

scientific article

Colorectal cancer proteomics, molecular characterization and biomarker discovery.

scientific article published on 14 January 2010

Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis.

scientific article published on 5 January 2017

Construction of an infectious genomic clone of porcine parvovirus: effect of the 5'-end on DNA replication.

scientific article published in August 1990

Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.

scientific article published on 13 September 2015

Data from proteomic characterization of the role of Snail1 in murine mesenchymal stem cells and 3T3-L1 fibroblasts differentiation

scientific article

Designing antibodies for the inhibition of gastrin activity in tumoral cell lines.

scientific article

Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis.

scientific article published on 24 February 2016

Differential phosphorylation patterns between the Cyclin-A2/CDK2 complex and their monomers.

scientific article published on 20 February 2009

Effect of different baculovirus inactivation procedures on the integrity and immunogenicity of porcine parvovirus-like particles.

scientific article

Effective induction of neutralizing antibodies with the amino terminus of VP2 of canine parvovirus as a synthetic peptide

scientific article published on 01 November 1994

Engineering parvovirus-like particles for the induction of B-cell, CD4(+) and CTL responses.

scientific article published in September 1999

Enhanced Missing Proteins Detection in NCI60 Cell Lines Using an Integrative Search Engine Approach

scientific article published on 29 September 2017

FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer

scientific article

Full protection against African horsesickness (AHS) in horses induced by baculovirus-derived AHS virus serotype 4 VP2, VP5 and VP7.

scientific article published on June 1996

Full protection in mink against mink enteritis virus with new generation canine parvovirus vaccines based on synthetic peptide or recombinant protein.

scientific article published in August 1995

Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature

scientific article published on 19 September 2013

Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer

scientific article published on 15 March 2016

IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.

scientific article

IL13Rα2 signaling in colorectal cancer

scientific article published on 12 September 2015

Identification and Validation of Stage-Associated Serum Biomarkers in Colorectal Cancer Using MS-Based Procedures

scientific article published on 18 September 2019

Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays.

scientific article

Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm

scientific article published on September 1996

Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.

scientific article published on 28 July 2009

In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity

scientific article

In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion.

scientific article published on 26 February 2013

Influence of flanking sequences on presentation efficiency of a CD8+ cytotoxic T-cell epitope delivered by parvovirus-like particles.

scientific article published in March 2004

LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.

scientific article published on 23 July 2015

Label-free nanoplasmonic sensing of tumor-associate autoantibodies for early diagnosis of colorectal cancer.

scientific article published on 4 May 2016

Mapping the antigenic structure of porcine parvovirus at the level of peptides.

scientific article published in February 1998

Mapping the spatial proteome of metastatic cells in colorectal cancer.

scientific article published on 31 August 2017

Minor displacements in the insertion site provoke major differences in the induction of antibody responses by chimeric parvovirus-like particles

scientific article published on 01 October 1999

Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.

scientific article

PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway

scientific article published on 17 May 2019

PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism

scientific article published on 18 January 2019

Parvovirus diagnostics and vaccine production in insect cells ⬇️

scientific article published on January 1, 1996

Parvovirus-like particles as vaccine vectors.

scientific article

Plant-derived vaccine protects target animals against a viral disease

scientific article published on 01 March 1997

Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4

scientific article published on 16 April 2020

Production of porcine parvovirus empty capsids with high immunogenic activity

scientific article published on January 1, 1992

Prognostic role of tissue transglutaminase 2 in colon carcinoma

scientific article published on 13 September 2016

Proteome analysis of membrane fractions in colorectal carcinomas by using 2D-DIGE saturation labeling.

scientific article published on 16 August 2008

Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.

scientific article published on 11 September 2013

Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer.

scientific article published on 13 November 2017

Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin

scientific article published on 11 January 2019

Proteomic analysis of 1α,25-dihydroxyvitamin D3 action on human colon cancer cells reveals a link to splicing regulation.

scientific article

Proteomic analysis of p38alpha mitogen-activated protein kinase-regulated changes in membrane fractions of RAS-transformed fibroblasts.

scientific article published in April 2006

Proteomic expression analysis of colorectal cancer by two-dimensional differential gel electrophoresis.

scientific article published in July 2005

Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.

scientific article

Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project

scientific article published on 15 June 2015

RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison

scientific article published on 17 April 2018

Recombinant parvovirus-like particles as an antigen carrier: a novel nonreplicative exogenous antigen to elicit protective antiviral cytotoxic T cells.

scientific article published on July 1997

Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis

scientific article published in Journal of Biological Chemistry

SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue.

scientific article published on December 2009

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166

scientific article published on 15 August 2020

Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells.

scientific article

Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis

scientific article published on 08 August 2016

Spanish human proteome project: dissection of chromosome 16.

scientific article published on 12 December 2012

Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis

scientific article published on 15 October 2013

Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines

scientific article published in May 2003

Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines.

scientific article

Subunit interface of triosephosphate isomerase: site-directed mutagenesis and characterization of the altered enzyme

scientific article published on 01 March 1987

Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome.

scientific article published on 5 November 2013

Synthetic peptide vaccines: success at last

scientific article published on 01 July 1995

TRIM72 Immunohistochemical Expression Can Predict Relapse in Colorectal Carcinoma

scientific article published on 09 March 2019

Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation.

scientific article published on September 2005

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases

scientific article

The mechanisms of planar cell polarity, growth and the Hippo pathway: some known unknowns

scientific article published on May 2013

Topographical analysis of canine parvovirus virions and recombinant VP2 capsids

scientific article published on 01 September 1993

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

scientific article published on 14 March 2016

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers.

scientific article published on 9 December 2016

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

scientific article published on 13 December 2016

c-Met Signaling Is Essential for Mouse Adult Liver Progenitor Cells Expansion After Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition and Regulates Cell Phenotypic Switch.

scientific article

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