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List of works by Mariana Brait

A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA.

scientific article published on 29 August 2017

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma

scientific article

Aberrant promoter methylation can be useful as a marker of recurrent disease in patients with cervical intraepithelial neoplasia grade III.

scientific article

Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.

scientific article published on October 2008

Abstract 527: Analysis of the interaction between microRNAs and Notch pathway members in HNSCC (head and neck squamous cell carcinoma)

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

scientific article published on 14 August 2016

Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma.

scientific article published on 19 September 2017

An epigenetic marker panel for detection of lung cancer using cell-free serum DNA.

scientific article

An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine

scientific article

An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation.

scientific article

Association between lifestyle factors and CpG island methylation in a cancer-free population.

scientific article

Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.

scientific article

Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma

scientific article

Cancer epigenetics: above and beyond

scientific article published in May 2011

Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression

scientific article published on 29 September 2009

Comparative mutational landscape analysis of patient-derived tumour xenografts

scientific article published on 24 January 2017

Correction: Association of Promoter Methylation of and with Ovarian Cancer Progression

article published in 2013

Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

scientific article published on 29 October 2013

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer

scientific article

Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

scientific article

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma

scientific article

Detection of Merkel cell virus and correlation with histologic presence of Merkel cell carcinoma in sentinel lymph nodes.

scientific article published on 13 March 2012

Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance

scientific article published on 31 May 2011

Downregulation of insulin-like growth factor-binding protein 7 in cisplatin-resistant non-small cell lung cancer

scientific article published on February 1, 2012

EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions.

scientific article published on May 2013

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine.

scientific article

Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration

scientific article

Epigenetic silencing of S100A2 in bladder and head and neck cancers

scientific article published on 16 March 2015

Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.

scientific article published on January 2008

Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma

scientific article

Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.

scientific article published on 17 February 2017

GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer

scientific article

GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma

scientific article published on 18 August 2020

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer

scientific article published on December 1, 2010

Genome-wide analysis of genetic alterations in testicular primary seminoma using high resolution single nucleotide polymorphism arrays

scientific article published on 02 March 2011

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials

scientific article

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma

scientific article published on February 22, 2013

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

scientific article

Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile.

scientific article

High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing

scientific article published on 31 March 2016

Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening

scientific article published on 18 May 2016

Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1

scientific article published on 28 June 2018

Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.

scientific article

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses

scientific article

MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients

scientific article published on 10 August 2016

Milk derived colloid as a novel drug delivery carrier for breast cancer

scientific article

Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR

scientific article

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

scientific article published on 6 August 2010

Notch1 mutations are drivers of oral tumorigenesis

scientific article

Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients

scientific article published on 28 January 2017

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission

scientific article published on June 2010

Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma

scientific article published on 30 June 2020

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling

scientific article published on 12 September 2012

Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA

scientific article

The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors

scientific article published on 15 May 2014

Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection

scientific article published on 16 December 2019

Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.

scientific article published on 20 December 2007

Tobacco and alcohol-induced epigenetic changes in oral carcinoma.

scientific article published on 13 March 2018

p16 gene methylation lacks correlation with angiogenesis and prognosis in multiple myeloma

scientific article published on 11 November 2004