List of works - Bradley Doak

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

scientific article published on 31 December 2018

Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA

scientific article

Cell permeability beyond the rule of 5.

scientific article

Cyclophilin Succumbs to a Macrocyclic Chameleon

scientific article published on 25 October 2018

Design of a Fragment-Screening Library

scientific article published on 19 October 2018

Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data

scientific article

Drug discovery beyond the rule of 5 - Opportunities and challenges.

scientific article

Erratum: Structural and conformational determinants of macrocycle cell permeability

scientific article published on 01 July 2017

How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets.

scientific article published on 12 October 2015

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

scientific article published on 2 April 2018

Opportunities and guidelines for discovery of orally absorbed drugs in beyond rule of 5 space

scientific article published on 25 May 2018

Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates.

scientific article

Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

scientific article published on 04 September 2018

Structural and conformational determinants of macrocycle cell permeability

scientific article published on 17 October 2016

Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis

scientific article

Synthesis of Unsymmetrical 1,1′-Disubstituted Bis(1,2,3-triazole)s Using Monosilylbutadiynes

scientific article published on 12 January 2011

The ways and means of fragment-based drug design

scientific article

List of works by Bradley Doak

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA

Cell permeability beyond the rule of 5.

Cyclophilin Succumbs to a Macrocyclic Chameleon

Design of a Fragment-Screening Library

Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data

Drug discovery beyond the rule of 5 - Opportunities and challenges.

Erratum: Structural and conformational determinants of macrocycle cell permeability

How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets.

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Opportunities and guidelines for discovery of orally absorbed drugs in beyond rule of 5 space

Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates.

Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

Structural and conformational determinants of macrocycle cell permeability

Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis

Synthesis of Unsymmetrical 1,1′-Disubstituted Bis(1,2,3-triazole)s Using Monosilylbutadiynes

The ways and means of fragment-based drug design