List of works - Stephan Gruber

4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts

scientific article published on 2 December 2024

4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts

scientific article published on 17 June 2024

A Chromosome Co-Entrapment Assay to Study Topological Protein-DNA Interactions

scientific article published in January 2017

A conserved antigen induces respiratory Th17-mediated serotype-independent protection against pneumococcal superinfection

scientific article published on 7 July 2023

A joint-ParB interface promotes Smc DNA recruitment

scientific article published in 2022

A low Smc flux avoids collisions and facilitates chromosome organization in

scientific article published on 4 August 2021

A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis

scientific article published on 4 August 2021

A rod conformation of the Pyrococcus furiosus Rad50 coiled coil

scientific article published on 02 September 2020

ATP hydrolysis is required for cohesin's association with chromosomes

scientific article published in November 2003

An asymmetric SMC-kleisin bridge in prokaryotic condensin

scientific article

Author Correction: Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells

scientific article published on 16 April 2024

CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA

scientific article published in September 2021

Chromosomal cohesin forms a ring

scientific article (publication date: 21 March 2003)

Chromosome remodelling by SMC/Condensin in is regulated by monomeric Soj/ParA during growth and sporulation

scientific article published on 11 October 2022

Closing the cohesin ring: structure and function of its Smc3-kleisin interface

scientific article

Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit

scientific article

Connecting the dots: key insights on ParB for chromosome segregation from single-molecule studies

scientific article published on 23 December 2023

Control of Smc Coiled Coil Architecture by the ATPase Heads Facilitates Targeting to Chromosomal ParB/parS and Release onto Flanking DNA.

scientific article

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

scientific article

DNA segment capture by Smc5/6 holo-complexes

scientific article published on 10 October 2022

DNA segment capture by Smc5/6 holocomplexes

scientific article published in May 2023

DNA supercoiling enhances DNA condensation by ParB proteins

scientific article published on 23 October 2024

DNA supercoiling enhances DNA condensation by ParB proteins

preprint published on 13 July 2024

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

scientific article published on 01 May 2022

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

scientific article published on 16 March 2021

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

scientific article published in December 2022

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

scientific article published on 5 October 2022

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

scientific article published on 01 July 2019

Decision Making in Phagocytosis

scientific article published on 01 January 2020

Direct observation of a crescent-shape chromosome in Bacillus subtilis

Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells

scientific article published on 28 March 2024

Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19.

scientific article

Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

scientific article published on 27 November 2023

Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

preprint published on 25 June 2023

Evidence for binary Smc complexes lacking kite subunits in archaea

scientific article published on 16 January 2020

Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge

article

Fine-tuning of the Smc flux facilitates chromosome organization in B. subtilis

scientific article published on 4 December 2020

Gradual opening of Smc arms in prokaryotic condensin

scientific article published on 21 January 2021

Gradual opening of Smc arms in prokaryotic condensin

scientific article published in April 2021

High-Throughput Allelic Replacement Screening in Bacillus subtilis

scientific article published on 01 January 2019

Inferring permafrost and permafrost thaw in the mountains of the Hindu Kush Himalaya region

scholarly article by Stephan Gruber et al published 13 January 2017 in The Cryosphere

Interlinked sister chromosomes arise in the absence of condensin during fast replication in B. subtilis

scientific article published on 16 January 2014

Is chromatin remodeling required to build sister-chromatid cohesion?

scientific article published in August 2004

Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes

scientific article

Molecular basis for SMC rod formation and its dissolution upon DNA binding

scientific article

MukBEF on the march: taking over chromosome organization in bacteria? ⬇️

scientific article published on July 20, 2011

Multilayer chromosome organization through DNA bending, bridging and extrusion

scientific article

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

scientific article published on 30 June 2021

Nse5/6 inhibits the Smc5/6 ATPase to facilitate DNA substrate selection

scientific article published on 9 February 2021

Optimization of sample preparation and green color imaging using the mNeonGreen fluorescent protein in bacterial cells for photoactivated localization microscopy.

scientific article published on 4 July 2018

Orchestrated long-distance gene activation by a ParB-like BisD-CTP DNA clamp in low-frequency transfer competence development in Pseudomonas putida

scientific article published on 16 September 2024

ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

scientific article published in July 2022

ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

ParS -independent recruitment of the bacterial chromosome-partitioning protein ParB

Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

scientific article published on 18 August 2020

Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

scientific article published on 16 December 2019

Recruitment of condensin to replication origin regions by ParB/SpoOJ promotes chromosome segregation in B. subtilis

scientific article published in May 2009

Relief of ParB autoinhibition by <i>parS</i> DNA catalysis and recycling of ParB by CTP hydrolysis promote bacterial centromere assembly

scientific article published on 06 October 2021

Relief of ParB autoinhibition by parS DNA catalysis and ParB recycling by CTP hydrolysis promote bacterial centromere assembly

scientific article published on 5 May 2021

SMC complexes sweeping through the chromosome: going with the flow and against the tide

scientific article published on 25 November 2017

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

scientific article published on 7 May 2015

SMC condensin: promoting cohesion of replicon arms

scientific article published on 01 September 2015

SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae

scientific article published on 22 June 2011

SMC-based immunity against extrachromosomal DNA elements

scientific article published on 31 August 2023

Self-organization of parS centromeres by the ParB CTP hydrolase

scientific article

Separate Compartments for Chromosome Entrapment and DNA Binding during SMC translocation

scientific article published on 13 December 2018

Shaping chromosomes by DNA capture and release: gating the SMC rings.

scientific article

SnapShot: SMC Protein Complexes Part I.

scientific article published in January 2016

SnapShot: SMC Protein Complexes Part II.

scientific article published in February 2016

Structural basis for plasmid restriction by SMC JET nuclease

scientific article published in March 2024

Structural basis for plasmid restriction by SMC JET nuclease

scientific article published on 3 November 2023

Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization.

scientific article published on July 2017

The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae

scientific article published on 30 June 2015

The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains

scientific article published on 5 January 2018

Transient DNA Occupancy of the SMC Interarm Space in Prokaryotic Condensin

scientific article published on 11 June 2019

Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin.

scientific article

VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor

scientific article published on 25 November 2023

VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor

preprint

List of works by Stephan Gruber

4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts

4G cloning: rapid gene assembly for expression of multisubunit protein complexes in diverse hosts

A Chromosome Co-Entrapment Assay to Study Topological Protein-DNA Interactions

A conserved antigen induces respiratory Th17-mediated serotype-independent protection against pneumococcal superinfection

A joint-ParB interface promotes Smc DNA recruitment

A low Smc flux avoids collisions and facilitates chromosome organization in

A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis

A rod conformation of the Pyrococcus furiosus Rad50 coiled coil

ATP hydrolysis is required for cohesin's association with chromosomes

An asymmetric SMC-kleisin bridge in prokaryotic condensin

Author Correction: Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells

CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA

Chromosomal cohesin forms a ring

Chromosome remodelling by SMC/Condensin in is regulated by monomeric Soj/ParA during growth and sporulation

Closing the cohesin ring: structure and function of its Smc3-kleisin interface

Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit

Connecting the dots: key insights on ParB for chromosome segregation from single-molecule studies

Control of Smc Coiled Coil Architecture by the ATPase Heads Facilitates Targeting to Chromosomal ParB/parS and Release onto Flanking DNA.

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

DNA segment capture by Smc5/6 holo-complexes

DNA segment capture by Smc5/6 holocomplexes

DNA supercoiling enhances DNA condensation by ParB proteins

DNA supercoiling enhances DNA condensation by ParB proteins

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

Decision Making in Phagocytosis

Direct observation of a crescent-shape chromosome in Bacillus subtilis

Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells

Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19.

Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

Evidence for binary Smc complexes lacking kite subunits in archaea

Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge

Fine-tuning of the Smc flux facilitates chromosome organization in B. subtilis

Gradual opening of Smc arms in prokaryotic condensin

Gradual opening of Smc arms in prokaryotic condensin

High-Throughput Allelic Replacement Screening in Bacillus subtilis

Inferring permafrost and permafrost thaw in the mountains of the Hindu Kush Himalaya region

Interlinked sister chromosomes arise in the absence of condensin during fast replication in B. subtilis

Is chromatin remodeling required to build sister-chromatid cohesion?

Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes

Molecular basis for SMC rod formation and its dissolution upon DNA binding

MukBEF on the march: taking over chromosome organization in bacteria? ⬇️

Multilayer chromosome organization through DNA bending, bridging and extrusion

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

Nse5/6 inhibits the Smc5/6 ATPase to facilitate DNA substrate selection

Optimization of sample preparation and green color imaging using the mNeonGreen fluorescent protein in bacterial cells for photoactivated localization microscopy.

Orchestrated long-distance gene activation by a ParB-like BisD-CTP DNA clamp in low-frequency transfer competence development in Pseudomonas putida

ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

ParS -independent recruitment of the bacterial chromosome-partitioning protein ParB

Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

Recruitment of condensin to replication origin regions by ParB/SpoOJ promotes chromosome segregation in B. subtilis

Relief of ParB autoinhibition by <i>parS</i> DNA catalysis and recycling of ParB by CTP hydrolysis promote bacterial centromere assembly

Relief of ParB autoinhibition by parS DNA catalysis and ParB recycling by CTP hydrolysis promote bacterial centromere assembly

SMC complexes sweeping through the chromosome: going with the flow and against the tide

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

SMC condensin: promoting cohesion of replicon arms

SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae

SMC-based immunity against extrachromosomal DNA elements

Self-organization of parS centromeres by the ParB CTP hydrolase

Separate Compartments for Chromosome Entrapment and DNA Binding during SMC translocation

Shaping chromosomes by DNA capture and release: gating the SMC rings.

SnapShot: SMC Protein Complexes Part I.

SnapShot: SMC Protein Complexes Part II.

Structural basis for plasmid restriction by SMC JET nuclease

Structural basis for plasmid restriction by SMC JET nuclease

Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization.

The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae

The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains

Transient DNA Occupancy of the SMC Interarm Space in Prokaryotic Condensin

Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin.

VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor

VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor