Search filters

List of works by Robert J. Heine

2.P.206 Hyperhomocysteinaemia attributes to 10 percent of all cardiovascular disease in a 50–75 year-old Caucasian population

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A combination of high concentrations of serum triglyceride and non-high-density-lipoprotein-cholesterol is a risk factor for cardiovascular disease in subjects with abnormal glucose metabolism--The Hoorn Study

scientific article

A comparison of the artificial pancreas (glucose controlled insulin infusion system) and a manual technique for assessing insulin sensitivity during euglycaemic clamping

scientific article published in June 1984

A comparison of the effects of semisynthetic human insulin and porcine insulin on transmembrane ion shifts and glucose metabolism during euglycaemic clamping ⬇️

scientific article published on 01 June 1984

A comparison of the standard and the computerized versions of the Well-being Questionnaire (WBQ) and the Diabetes Treatment Satisfaction Questionnaire (DTSQ)

scientific article published on 01 January 1998

A prospective study of dairy consumption in relation to changes in metabolic risk factors: the Hoorn Study

scientific article published on 17 January 2008

A randomized trial of continuous subcutaneous insulin infusion and intensive injection therapy in type 1 diabetes for patients with long-standing poor glycemic control

scientific article published in November 2002

A randomized trial of insulin aspart with intensified basal NPH insulin supplementation in people with Type 1 diabetes

scientific article published in April 2003

A study of the effects of acarbose on glucose metabolism in patients predisposed to developing diabetes: the Dutch acarbose intervention study in persons with impaired glucose tolerance (DAISI).

scientific article

Absence of an acute insulin response predicts onset of type 2 diabetes in a Caucasian population with impaired glucose tolerance

scientific article published on 6 May 2008

Absorption kinetics and action profiles after sequential subcutaneous administration of human soluble and lente insulin through one needle

scientific article published on 01 July 1987

Absorption kinetics and action profiles of intermediate acting human insulins

scientific article published on 01 January 1987

Absorption kinetics and action profiles of mixtures of short- and intermediate-acting insulins

scientific article published on 01 December 1984

Absorption kinetics of short- and intermediate-acting insulins after jet injection with Medi-Jector II

scientific article published on 01 October 1988

Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men.

scientific article published on 2 February 2010

Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

scientific article

Acute elevation of plasma non-esterified fatty acids increases pulse wave velocity and induces peripheral vasodilation in humans in vivo

scientific article

Acute hyperinsulinemia induces sodium retention and a blood pressure decline in diabetes mellitus ⬇️

scientific article published on August 1, 1992

Admission blood glucose level as risk indicator of death after myocardial infarction in patients with and without diabetes mellitus

scientific article

Alanine aminotransferase and the 6-year risk of the metabolic syndrome in Caucasian men and women: the Hoorn Study

scientific article published on April 2007

Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease

scientific article published on November 2006

Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study

article

Albuminuria, but not estimated glomerular filtration rate, is associated with maladaptive arterial remodeling: the Hoorn Study

scientific article published in April 2008

Altered beta-cell characteristics in impaired glucose tolerant carriers of a GAA trinucleotide repeat polymorphism in the frataxin gene

article

Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging

scientific article published in October 2009

An exploratory analysis of criteria for the metabolic syndrome and its prediction of long-term cardiovascular outcomes: the Hoorn study

scientific article published on 2 August 2005

Analogs of glucagon-like peptide-1 (GLP-1): an old concept as a new treatment of patients with diabetes mellitus type 2

scientific article

Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis

scientific article

Are insulin resistance, impaired fasting glucose and impaired glucose tolerance all equally strongly related to age?

scientific article published in November 2005

Are retinal microvascular abnormalities associated with large artery endothelial dysfunction and intima-media thickness? The Hoorn Study

scientific article published on May 2006

Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn Study

scientific article published on 14 April 2003

Assessing impaired hypoglycemia awareness in type 1 diabetes: agreement of self-report but not of field study data with the autonomic symptom threshold during experimental hypoglycemia

scientific article

Assessment of perceived barriers in self-care of insulin-requiring diabetic patients

scientific article published in December 1996

Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels

scientific article published on 4 November 2009

Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: a population-based study.

scientific article published in November 1996

Associations between depressive symptoms and insulin resistance: the Hoorn Study

scientific article published on 26 October 2006

Associations between features of glucose exposure and A1C: the A1C-Derived Average Glucose (ADAG) study ⬇️

scientific article

Associations of LDL size with in vitro oxidizability and plasma levels of in vivo oxidized LDL in Type 2 diabetic patients

scientific article

Associations of adiponectin levels with incident impaired glucose metabolism and type 2 diabetes in older men and women: the hoorn study

scientific article published in November 2006

Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study

article

Associations of metabolic variables with arterial stiffness in type 2 diabetes mellitus: focus on insulin sensitivity and postprandial triglyceridaemia

scientific article published in April 2003

Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial ⬇️

scientific article published on May 6, 2011

Beyond postprandial hyperglycaemia: metabolic factors associated with cardiovascular disease

scientific article

Biological and behavioural determinants of the frequency of mild, biochemical hypoglycaemia in patients with Type 1 diabetes on multiple insulin injection therapy

scientific article published on 01 May 2000

Blood lipid levels in relation to glucose status in European men and women without a prior history of diabetes: the DECODE Study

scientific article

Blood pressure levels in pre-diabetic stages are associated with worse cognitive functioning in patients with type 2 diabetes

scientific article published in October 2009

Blood pressure, lipids, and obesity are associated with retinopathy: the hoorn study

scientific article published in August 2002

Body composition, insulin sensitivity, and cardiovascular disease profile in healthy Europeans

scientific article

Brachial artery pulse pressure and common carotid artery diameter: mutually independent associations with mortality in subjects with a recent history of impaired glucose tolerance

scientific article

C-reactive protein and soluble vascular cell adhesion molecule-1 are associated with elevated urinary albumin excretion but do not explain its link with cardiovascular risk

scientific article

Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats

scientific article published on 30 April 2005

Cardiovascular autonomic function is associated with (micro-)albuminuria in elderly Caucasian sujects with impaired glucose tolerance or type 2 diabetes: the Hoorn Study

scholarly article by Y M Smulders et al published 1 September 2000 in Diabetes Care

Cardiovascular events in type 2 diabetes: comparison with nondiabetic individuals without and with prior cardiovascular disease. 10-year follow-up of the Hoorn Study

scientific article published in August 2003

Cardiovascular risk factors prior to the development of non-insulin-dependent diabetes mellitus in persons with impaired glucose tolerance: the Hoorn Study

scientific article published in September 1997

Carotid arterial remodeling: a maladaptive phenomenon in type 2 diabetes but not in impaired glucose metabolism: the Hoorn study

scientific article published on 12 February 2004

Carotid artery stenosis is related to blood glucose level in an elderly Caucasian population: the Hoorn Study

scientific article published in March 1997

Ceiling effect reduces the validity of the Diabetes Treatment Satisfaction Questionnaire

scientific article published in November 1998

Change in common carotid artery diameter, distensibility and compliance in subjects with a recent history of impaired glucose tolerance: a 3-year follow-up study

scientific article

Circulating oxidized LDL: determinants and association with brachial flow-mediated dilation

scientific article

Classical and model-based estimates of beta-cell function during a mixed meal vs. an OGTT in a population-based cohort

scientific article

Clinical significance of the physicochemical properties of LDL in type 2 diabetes

scientific article

Coffee consumption and incidence of impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes: the Hoorn Study

scientific article published on 11 December 2004

Cognitive behavioural group training (CBGT) for patients with type 1 diabetes in persistent poor glycaemic control: who do we reach?

scientific article published in March 2005

Cognitive behavioural therapy (CBT) compared with blood glucose awareness training (BGAT) in poorly controlled Type 1 diabetic patients: long-term effects on HbA moderated by depression. A randomized controlled trial

scientific article

Cognitive functioning in elderly persons with type 2 diabetes and metabolic syndrome: the Hoorn study

scientific article published on 8 October 2008

Cognitive performance in type 1 diabetes patients is associated with cerebral white matter volume

scientific article published on 2 June 2007

Combined bedtime insulin--daytime sulphonylurea regimen compared with two different daily insulin regimens in type 2 diabetes: effects on HbA1c and hypoglycaemia rate--a randomised trial

scientific article published in March 2003

Combined data from LDL composition and size measurement are compatible with a discoid particle shape

scientific article

Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps

scientific article

Comment on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604

scientific article published on October 2013

Comment on: Schmidt MI, Duncan BB, Vigo A et al (2006) Leptin and incident type 2 diabetes: risk or protection? Diabetologia 49:2086-2096.

scientific article

Comparison of three methods for measuring LDL resistance against copper-induced oxidation

scientific article published on 01 February 2000

Comparison of three methods for the quantification of beta-cell function and insulin sensitivity

scientific article published in December 1994

Comparison of two commonly used insulin injection techniques

scientific article published on 01 May 1985

Comparison of two consecutive fat-rich and carbohydrate-rich meals on postprandial myeloperoxidase response in women with and without type 2 diabetes mellitus

scientific article

Components of the insulin resistance syndrome in seven-year-old children: relations with birth weight and the polyunsaturated fatty acid content of umbilical cord plasma phospholipids

scientific article published in March 2002

Composition of LDL as determinant of its susceptibility to in vitro oxidation in patients with well‐controlled type 2 diabetes ⬇️

scientific article published on November 1, 2001

Continuous intraperitoneal insulin infusion in patients with 'brittle' diabetes: favourable effects on glycaemic control and hospital stay.

scientific article published in June 2002

Corrigendum to “Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals The Hoorn Study” [Atherosclerosis 169 (2003) 323-330]

scholarly article published in Atherosclerosis

Counterregulatory hormone responses and symptoms during hypoglycaemia induced by porcine, human regular insulin, and Lys(B28), Pro(B29) human insulin analogue (insulin Lispro) in healthy male volunteers

scientific article published on 01 March 1997

Delayed onset of action of soluble insulin after premixing with U100 lente insulin

scientific article published on 01 November 1986

Deteriorating glucose tolerance status is associated with left ventricular dysfunction--the Hoorn Study.

scientific article

Determinants of insulin sensitivity and consequences for lipoproteins and blood pressure in subjects with non-insulin-dependent diabetes mellitus

scientific article published in April 1994

Determinants of postprandial triglyceride and glucose responses after two consecutive fat-rich or carbohydrate-rich meals in normoglycemic women and in women with type 2 diabetes mellitus: the Hoorn Prandial Study

scientific article published in September 2008

Determinants of specific serum insulin concentrations in a general Caucasian population aged 50 to 74 years (the Hoorn Study).

scientific article published in January 1998

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

scientific article

Development and validation of the diabetes fear of injecting and self-testing questionnaire (D-FISQ): first findings

scientific article published in October 1997

Development of a Type 2 Diabetes Symptom Checklist: a Measure of Symptom Severity

article

Diabetes Fear of Injecting and Self-Testing Questionnaire: a psychometric evaluation

scientific article published in June 2000

Diabetes monitoring system in The Netherlands

scientific article published on October 1996

Diabetes, prediabetes and cancer mortality

scientific article published on 21 May 2010

Diabetes, pulse pressure and cardiovascular mortality: the Hoorn Study

scholarly article by Miranda T Schram et al published September 2002 in Journal of Hypertension

Diabetes-related symptom distress in association with glucose metabolism and comorbidity: the Hoorn Study

scientific article published on 26 August 2008

Diabetes-related symptoms and negative mood in participants of a targeted population-screening program for type 2 diabetes: The Hoorn Screening Study

scientific article published in August 2005

Diabetes-specific emotional distress mediates the association between depressive symptoms and glycaemic control in Type 1 and Type 2 diabetes

scientific article

Diabetic encephalopathy: A concept in need of a definition

scientific article published on 6 April 2006

Diabetic patients detected by population-based stepwise screening already have a diabetic cardiovascular risk profile

scientific article published in October 2002

Dietary (n-3) polyunsaturated fatty acids lower plasma triacyglycerol concentrations in non-insulin-dependent diabetes mellitus

scientific article published on 01 September 1986

Dietary polyunsaturated fat intake is associated with low-density lipoprotein size, but not with susceptibility to oxidation in subjects with impaired glucose metabolism and type II diabetes: the Hoorn study

scientific article published on 30 August 2006

Dietary supplementation of omega-3 polyunsaturated fatty acids improves insulin sensitivity in non-insulin-dependent diabetes

scientific article published on 01 March 1987

Dissimilar association of conventional immuno-reactive versus specific insulin with cardiovascular risk factors: a consequence of proinsulinaemia?

scientific article published in May 1998

Does Glucose Variability Influence the Relationship Between Mean Plasma Glucose and HbA1c Levels in Type 1 and Type 2 Diabetic Patients? ⬇️

scientific article published on June 23, 2011

Does metformin increase the serum total homocysteine level in non-insulin-dependent diabetes mellitus?

scientific article published in November 1997

Drug therapy for management of obesity

scientific article published in April 2001

Effect of 3 Years of Treatment With Exenatide on Postprandial Glucagon Levels

scientific article published on 30 December 2015

Effect of moderate alcohol consumption on adiponectin, tumor necrosis factor-alpha, and insulin sensitivity

scientific article published in January 2004

Effectiveness of insulin therapy in people with Type 2 diabetes in the Hoorn Diabetes Care System

scientific article published on 4 March 2016

Effects of cognitive behavioural group training (CBGT) in adult patients with poorly controlled insulin-dependent (type 1) diabetes: a pilot study ⬇️

scientific article published on November 1, 2001

Effects of exenatide on measures of β-cell function after 3 years in metformin-treated patients with type 2 diabetes

scientific article

Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well‐controlled type 2 diabetes patients* ⬇️

scientific article published on June 1, 2012

Elevated cholesteryl ester transfer protein concentration is associated with an increased risk for cardiovascular disease in women, but not in men, with Type 2 diabetes: the Hoorn Study

scientific article published in February 2007

Endothelial dysfunction and low-grade inflammation explain much of the excess cardiovascular mortality in individuals with type 2 diabetes: the Hoorn Study

scientific article published on 2 March 2006

Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: the Hoorn study

scientific article published on 28 December 2005

Estimate of the number of new patients with type 2 diabetes mellitus in the Netherlands: at least 65,000 per year in the age group of 50 years and above

scientific article published in July 2003

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

scientific article

Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition

scientific article

Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes

scientific article published in April 2011

Exogenous insulin augments in healthy volunteers the cardiovascular reactivity to noradrenaline but not to angiotensin II ⬇️

scientific article published on August 1, 1991

Fasting and postprandial glycoxidative and lipoxidative stress are increased in women with type 2 diabetes

scientific article published on 27 April 2007

Fasting cholesteryl ester transfer protein concentration is independently associated with the postprandial decrease in high-density lipoprotein cholesterol concentration after fat-rich meals: the Hoorn prandial study

scientific article published on 16 December 2009

Fasting proinsulin and 2-h post-load glucose levels predict the conversion to NIDDM in subjects with impaired glucose tolerance: the Hoorn Study.

scientific article published on January 1996

Fat food for a bad mood. Could we treat and prevent depression in Type 2 diabetes by means of omega-3 polyunsaturated fatty acids? A review of the evidence

scientific article

Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: a new concept in the pathogenesis of obesity-associated type 2 diabetes mellitus

scientific article published on 22 August 2007

Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: do adipocytes consume sufficient amounts of oxygen to oxidise fatty acids?

scientific article published on 4 March 2008

Finnish questionnaire reasonably good predictor of the incidence of diabetes in The Netherlands

scientific article published in November 2008

Fish Oil and Glycemic Control in Diabetes: A meta-analysis ⬇️

scientific article published on April 1, 1998

Fish oil and glycemic control: importance of dose

scientific article published on 01 January 1990

From the Cochrane Library and Diabetes Care: self-monitoring of blood glucose probably an effective way to improve glycaemic control in patients with type 2 diabetes not taking insulin

scientific article published in August 2006

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

scientific article

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study

scientific article

Genetic factors and insulin secretion: gene variants in the IGF genes

scientific article published in February 2004

Genetic influences on the insulin response of the beta cell to different secretagogues

scientific article published on 3 October 2009

Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men

article

Glucose tolerance and other determinants of cardiovascular autonomic function: the Hoorn Study

scientific article published on 01 May 2000

Glycemic Control and Complications in Type II Diabetes

Glycemic control and complications in type II diabetes

HbA1c is an independent predictor of non-fatal cardiovascular disease in a Caucasian population without diabetes: a 10-year follow-up of the Hoorn Study

scientific article published on 28 January 2011

Health-related quality of life in the first year following diagnosis of Type 2 diabetes: newly diagnosed patients in general practice compared with screening-detected patients. The Hoorn Screening Study

scientific article published in October 2004

Hepatic 123I-insulin binding kinetics in non-insulin-dependent (type 2) diabetic patients after i.v. bolus administration

scientific article published on 01 January 1989

High risk of cardiovascular mortality in individuals with impaired fasting glucose is explained by conversion to diabetes: the Hoorn study

scientific article published on February 2007

Homocysteine levels are not associated with cardiovascular autonomic function in elderly Caucasian subjects without or with type 2 diabetes mellitus: the Hoorn Study

scientific article published in December 2005

Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study

scientific article published in April 2008

How valid is fasting plasma glucose as a parameter of glycemic control in non-insulin-using patients with type 2 diabetes?

scientific article published in June 1999

Human insulin and hypoglycaemia

scientific article

Hyperglycaemia as a determinant of cognitive decline in patients with type 1 diabetes

scientific article published on 04 March 2008

Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn Study

scientific article published on August 1999

Hyperglycemia and oxidative stress strengthen the association between myeloperoxidase and blood pressure

scientific article published on 12 April 2010

Hyperglycemia and stroke mortality: comparison between fasting and 2-h glucose criteria

scientific article

Hyperhomocysteinaemia is associated with coronary events in type 2 diabetes

scientific article published in March 2003

Hyperhomocysteinaemia is not associated with isolated crural arterial occlusive disease: The Hoorn Study

scientific article

Hyperhomocysteinaemia is not related to risk of distal somatic polyneuropathy: the Hoorn Study

article

Hyperhomocysteinemia Is Associated With the Presence of Retinopathy in Type 2 Diabetes Mellitus

article

Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes : 5-year follow-up of the Hoorn Study

scientific article

Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study

scientific article published in January 1998

Hyperhomocysteinemia is associated with the presence of retinopathy in type 2 diabetes mellitus: the Hoorn study

article by E K Hoogeveen et al published 23 October 2000 in JAMA Internal Medicine

Hyperproinsulinaemia in impaired glucose tolerance is associated with a delayed insulin response to glucose

article

Hypoglycaemia induces emotional disruption

scientific article published in October 1996

Impact of diabetes duration and cardiovascular risk factors on mortality in type 2 diabetes: the Hoorn Study

scholarly article by A M W Spijkerman et al published December 2002 in European Journal of Clinical Investigation

Impaired autonomic function is associated with increased mortality, especially in subjects with diabetes, hypertension, or a history of cardiovascular disease: the Hoorn Study

scientific article published in October 2001

Impaired glucose tolerance and unidentified diabetes

scientific article published on February 1996

Improved glycaemic control in type 1 diabetes patients following participation per se in a clinical trial--mechanisms and implications.

scientific article

Improvement of glycaemic control in type 2 diabetes: favourable changes in blood pressure, total cholesterol and triglycerides, but not in HDL cholesterol, fibrinogen, Von Willebrand factor and (pro)insulin.

scientific article

Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus

scientific article published on May 2008

Increased central artery stiffness in impaired glucose metabolism and type 2 diabetes: the Hoorn Study

scientific article

Increased levels of soluble vascular cell adhesion molecule 1 are associated with risk of cardiovascular mortality in type 2 diabetes: the Hoorn study

scholarly article by A. Jager et al published 1 March 2000 in Diabetes

Increased plasma apolipoprotein C-III concentration independently predicts cardiovascular mortality: the Hoorn Study

scientific article published on 12 June 2008

Increasing incidence of type I diabetes in The Netherlands. The second nationwide study among children under 20 years of age.

scientific article published in June 1994

Incretin mimetics as a novel therapeutic option for hepatic steatosis

scientific article

Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study

scientific article published on 26 May 2005

Influence of salt on glycaemic response to carbohydrate loading

scientific article published on May 1987

Insulin Pump Therapy: a Meta-Analysis: Response to Weissberg-Benchell et al

article

Insulin and risk of cardiovascular disease: a meta-analysis

scientific article

Insulin pumps are still debatable for type 1 diabetes.

scientific article published on July 2002

Insulin sensitivity in hyperthyroidism: measurement by the glucose clamp technique

scientific article published on 01 April 1983

Insulin-treated diabetes patients with fear of self-injecting or fear of self-testing: psychological comorbidity and general well-being

scientific article published in November 2001

Interactions of dietary fat intake and the hepatic lipase -480C-->T polymorphism in determining hepatic lipase activity: the Hoorn Study

article

Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study

scientific article published in March 1996

Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study

article by J. M. Mooy et al published March 1996 in Diabetologia

Is higher dairy consumption associated with lower body weight and fewer metabolic disturbances? The Hoorn Study

scientific article

Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in Type II diabetes mellitus?

scientific article published in July 2001

Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

scientific article published on 17 November 2012

Kinetics of intermediate-acting insulins: clamp studies

scientific article published on 01 January 1985

LDL oxidative modifications in well- or moderately controlled type 2 diabetes

scientific article published in July 2004

Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus

scientific article

Larger thigh and hip circumferences are associated with better glucose tolerance: the Hoorn study

scientific article published in January 2003

Left ventricular mass increases with deteriorating glucose tolerance, especially in women: independence of increased arterial stiffness or decreased flow-mediated dilation: the Hoorn study

scientific article published in February 2004

Leptin and variables of body adiposity, energy balance, and insulin resistance in a population-based study. The Hoorn Study

scientific article published on July 1999

Letters to the editors

Limited effect of screening for depression with written feedback in outpatients with diabetes mellitus: a randomised controlled trial

scientific article

Linoleic-acid-enriched diet: long-term effects on serum lipoprotein and apolipoprotein concentrations and insulin sensitivity in noninsulin-dependent diabetic patients

scientific article

Liver alanine aminotransferase, insulin resistance and endothelial dysfunction in normotriglyceridaemic subjects with type 2 diabetes mellitus

scientific article published in June 2005

Longitudinal assessment of the development of diabetic polyneuropathy and associated risk factors

scientific article published on 01 September 2002

Low Prevalence of Antibodies to GAD65 in a 50- to 74-Year-Old General Dutch Population: The Hoorn Study

scientific article published on 01 July 1997

Major stressful life events in relation to prevalence of undetected type 2 diabetes: the Hoorn Study

article by J. M. Mooy et al published 1 February 2000 in Diabetes Care

Management of hyperglycaemia in type 2 diabetes: the end of recurrent failure?

scientific article published on December 2006

Meal composition affects insulin secretion in women with type 2 diabetes: a comparison with healthy controls. The Hoorn prandial study

scientific article published on 7 November 2007

Measurement of LDL particle size in whole plasma and serum by high performance gel-filtration chromatography using a fluorescent lipid probe ⬇️

scientific article published on October 1, 1998

Measurement of low-density lipoprotein particle size by high-performance gel-filtration chromatography ⬇️

scientific article published on October 1, 1997

Meta-analysis of the relationship between alcohol consumption and coronary heart disease and mortality in type 2 diabetic patients

scientific article

Metabolic Efficacy of Preprandial Administration of Lys(B28), Pro(B29) Human Insulin Analog in IDDM Patients: A comparison with human regular insulin during a three-meal test period ⬇️

scientific article published on August 1, 1997

Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study

scientific article published in August 2005

Metabolic syndrome: limited significance for clinical practice

scientific article published in April 2005

Michaela Diamant, 11 April 1962-9 April 2014.

scientific article published on 6 May 2014

Microalbuminuria and Peripheral Arterial Disease Are Independent Predictors of Cardiovascular and All-Cause Mortality, Especially Among Hypertensive Subjects

article

Microalbuminuria and cardiovascular autonomic dysfunction are independently associated with cardiovascular mortality: evidence for distinct pathways: the Hoorn Study

scientific article published on 29 June 2009

Microalbuminuria and peripheral arterial disease are independent predictors of cardiovascular and all-cause mortality, especially among hypertensive subjects: five-year follow-up of the Hoorn Study

scholarly article by A Jager et al published March 1999 in Arteriosclerosis, Thrombosis, and Vascular Biology

Microalbuminuria is associated with impaired brachial artery, flow-mediated vasodilation in elderly individuals without and with diabetes: further evidence for a link between microalbuminuria and endothelial dysfunction--the Hoorn Study

scientific article published in November 2004

Microalbuminuria is strongly associated with NIDDM and hypertension, but not with the insulin resistance syndrome: the Hoorn Study

scientific article published in June 1998

Microvascular complications at time of diagnosis of type 2 diabetes are similar among diabetic patients detected by targeted screening and patients newly diagnosed in general practice: the hoorn screening study

scientific article published in September 2003

Microvascular disease in type 1 diabetes alters brain activation: a functional magnetic resonance imaging study

scientific article published in February 2006

Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study

scientific article published in October 2002

Mild renal insufficiency is associated with increased left ventricular mass in men, but not in women: an arterial stiffness-related phenomenon--the Hoorn Study

scientific article published in August 2005

Mixing short and intermediate acting insulins in the syringe: effect on postprandial blood glucose concentrations in type I diabetics

scientific article published in January 1985

Moderate alcohol consumption is associated with lower risk for incident diabetes and mortality: the Hoorn Study

scientific article

Moderate alcohol consumption lowers the risk of type 2 diabetes: a meta-analysis of prospective observational studies

scientific article (publication date: March 2005)

Monitoring of psychological well-being in outpatients with diabetes: effects on mood, HbA(1c), and the patient's evaluation of the quality of diabetes care: a randomized controlled trial

scientific article published in November 2001

Multiple daily insulin injections improve self-confidence

scientific article published in August 1989

Neuropeptide Y polymorphism significantly magnifies diabetes and cardiovascular disease risk in obesity: the Hoorn Study

scientific article published on 28 November 2007

New data on the rate of progression of impaired glucose tolerance to NIDDM and predicting factors.

scientific article published on January 1996

Nighttime Insulin Kinetics and Glycemic Control in Type 1 Diabetes Patients Following Administration of an Intermediate-Acting Lispro Preparation ⬇️

scientific article published on December 1, 1997

No evidence for increased self-reported cognitive failure in Type 1 and Type 2 diabetes: a cross-sectional study

scientific article published on 2 April 2007

No independent association of alanine aminotransferase with risk of future type 2 diabetes in the Hoorn study

scientific article

No substantial psychological impact of the diagnosis of Type 2 diabetes following targeted population screening: The Hoorn Screening Study

scientific article

Non-HDL cholesterol contributes to the "hypertriglyceridemic waist" as a cardiovascular risk factor: the Hoorn study

scientific article published in January 2004

Nonalcoholic fatty liver disease and cardiovascular disease risk

scientific article published on June 2007

One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial

scientific article

One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress

scientific article published on 29 April 2010

Opposite contributions of trunk and leg fat mass with plasma lipase activities: the Hoorn study

scientific article

Optimized basal-bolus therapy using a fixed mixture of 75% lispro and 25% NPL insulin in type 1 diabetes patients: no favorable effects on glycemic control, physiological responses to hypoglycemia, well-being, or treatment satisfaction

scientific article published on 01 May 2000

Pancreatic fat content and beta-cell function in men with and without type 2 diabetes

scientific article published on 31 July 2007

Perceived risk for Type 2 diabetes in participants in a stepwise population-screening programme

scientific article published on 01 March 2003

Performance of an NIDDM screening questionnaire based on symptoms and risk factors

scientific article published in April 1997

Peripheral Somatic Nerve Function in Relation to Glucose Tolerance in an Elderly Caucasian Population: the Hoorn Study

scientific article published in November 1996

Peripheral arterial disease in relation to glycaemic level in an elderly Caucasian population: the Hoorn Study

Peripheral arterial disease in relation to glycaemic level in an elderly Caucasian population: the Hoorn study

scientific article published in January 1995

Peripheral somatic nerve function in relation to glucose tolerance in an elderly Caucasian population: the Hoorn study

scientific article published in November 1996

Persistent poor glycaemic control in adult Type 1 diabetes. A closer look at the problem

scientific article

Perspectives on Some Controversies in Cardiovascular Disease Risk Assessment in the Pharmaceutical Development of Glucose-Lowering Medications

scientific article published on August 2016

Pharmacokinetics and miscibility of 4 highly purified porcine insulins: a study in vitro and in healthy volunteers

scientific article published on 01 January 1987

Phobia of self-injecting and self-testing in insulin-treated diabetes patients: opportunities for screening

scientific article

Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study

scientific article published in August 2003

Plasma myeloperoxidase is inversely associated with endothelium-dependent vasodilation in elderly subjects with abnormal glucose metabolism

scientific article published on 23 May 2010

Plasma triglycerides and LDL cholesterol are related in a parabolic fashion in the general population and patients with Type 2 diabetes mellitus: long-term follow-up results from the Hoorn study

scientific article published in September 2008

Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies

scientific article published in July 2009

Postprandial dysmetabolism and cardiovascular disease in type 2 diabetes

scientific article published on January 2005

Postprandial glucose peaks in the pathogenesis of cardiovascular disease in diabetes mellitus; implications for metabolic control

scientific article

Prandial glucose regulation in the glucose triad: emerging evidence and insights

scientific article

Pravastatin compared to bezafibrate in the treatment of dyslipidemia in insulin-treated patients with type 2 diabetes mellitus

scientific article

Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study

scientific article published in September 1995

Prevalence of comorbid depression is high in out-patients with Type 1 or Type 2 diabetes mellitus. Results from three out-patient clinics in the Netherlands

scientific article published in February 2010

Prevalence of macrovascular disease amongst type 2 diabetic patients detected by targeted screening and patients newly diagnosed in general practice: the Hoorn Screening Study

scientific article published in November 2004

Prevalence of maternally inherited diabetes and deafness in diabetic populations in the Netherlands

scientific article published on 01 November 1994

Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study

scientific article published on 01 March 1999

Prevalences of hyperhomocysteinemia, unfavorable cholesterol profile and hypertension in European populations

scientific article

Prognostic Value of Adiponectin for Cardiovascular Disease and Mortality

article

Prognostic implications of retinopathy and a high plasma von Willebrand factor concentration in type 2 diabetic subjects with microalbuminuria.

scientific article

Proinsulin concentration is an independent predictor of all-cause and cardiovascular mortality: an 11-year follow-up of the Hoorn Study

scientific article published in April 2005

Prospective Relation of C-Reactive Protein With Type 2 Diabetes: Response to Han et al

article

Prospective investigation of metabolic characteristics in relation to weight gain in older adults: the Hoorn Study

scientific article published on 5 February 2009

Quality of care for patients with Type 2 diabetes mellitus—a long‐term comparison of two quality improvement programmes in the Netherlands ⬇️

scientific article published on October 1, 2003

Randomized study of two different target levels of glycemic control within the acceptable range in type 2 diabetes. Effects on well-being at 1 year

scientific article published in December 1998

Rates and risks for co-morbid depression in patients with Type 2 diabetes mellitus: results from a community-based study

scientific article published on 18 June 2003

Real-life glycaemic profiles in non-diabetic individuals with low fasting glucose and normal HbA1c: the A1C-Derived Average Glucose (ADAG) study

scientific article

Reduced second phase insulin secretion in carriers of a sulphonylurea receptor gene variant associating with Type II diabetes mellitus

article

Refractive properties of the healthy human eye during acute hyperglycemia

scientific article published on 4 April 2008

Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: The Hoorn Study

scientific article published in April 2001

Relationship between body mass index and mortality among Europeans ⬇️

article by X Song et al published 10 August 2011 in European Journal of Clinical Nutrition

Renal and Cardiovascular Effects of Exogenous Insulin in Healthy Volunteers ⬇️

scientific article published on 01 March 1991

Renal handling of urate and sodium during acute physiological hyperinsulinaemia in healthy subjects

scientific article published on 01 January 1997

Reproducibility of vibratory perception thresholds in patients with diabetic neuropathy

scientific article published on 01 November 1986

Responses to human and porcine insulin in healthy subjects

scientific article published on 01 October 1989

Retinopathy Is Associated With Cardiovascular and All-Cause Mortality in Both Diabetic and Nondiabetic Subjects: The Hoorn Study

scholarly article by M. V. van Hecke et al published 26 September 2003 in Diabetes Care

Retinopathy is associated with cardiovascular and all-cause mortality in both diabetic and nondiabetic subjects: the hoorn study

article

Retinopathy screening in type 2 diabetes: reliability of wide angle fundus photography

scientific article published in May 1996

Rheumatoid arthritis versus diabetes as a risk factor for cardiovascular disease: a cross-sectional study, the CARRE Investigation

scientific article published on 12 August 2008

Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoorn study

scientific article published in February 2003

S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations

scientific article

S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study

scientific article published on 3 February 2005

Sagittal abdominal diameter: no advantage compared with other anthropometric measures as a correlate of components of the metabolic syndrome in elderly from the Hoorn Study

scientific article published in November 2006

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

scientific article (publication date: 8 October 2005)

Self-Monitoring of Blood Glucose in Patients With Type 2 Diabetes Who Are Not Using Insulin: Response to Kleefstra et al. and Davidson

Self-monitoring by patients with type-2 diabetes mellitus one year after initiation: user errors in a quarter of cases

scientific article

Self-monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin

scientific article

Self-monitoring of blood glucose in patients with type 2 diabetes who are not using insulin: a systematic review

scientific article

Sensory Threshold Testing

scientific article published on 01 April 1993

Sensory thresholds in older adults: Reproducibility and reference values

article

Sequential infusions of glucose and insulin at prefixed rates: a simple method for assessing insulin sensitivity and insulin responsiveness.

scientific article

Serum homocysteine is weakly associated with von Willebrand factor and soluble vascular cell adhesion molecule 1, but not with C-reactive protein in type 2 diabetic and non-diabetic subjects - The Hoorn Study

Serum homocysteine level and protein intake are related to risk of microalbuminuria: the Hoorn Study

scientific article published in July 1998

Serum homocysteine levels are associated with the development of (micro)albuminuria: the Hoorn study

scientific article (publication date: 2001)

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility

scientific article

Short-term effects of cognitive behavioural group training (CBGT) in adult Type 1 diabetes patients in prolonged poor glycaemic control. A randomized controlled trial

scientific article published in November 2005

Similar 9-year mortality risks and reproducibility for the World Health Organization and American Diabetes Association glucose tolerance categories: the Hoorn Study

article by F. de Vegt et al published 1 January 2000 in Diabetes Care

Slightly elevated B-type natriuretic peptide levels in a non-heart failure range indicate a worse left ventricular diastolic function in individuals with, as compared with individuals without, type 2 diabetes: the Hoorn Study

scientific article published on 28 July 2010

Substitution of night-time continuous subcutaneous insulin infusion therapy for bedtime NPH insulin in a multiple injection regimen improves counterregulatory hormonal responses and warning symptoms of hypoglycaemia in IDDM ⬇️

scientific article published on 01 March 1998

Sustained good glycaemic control in NIDDM patients by implementation of structured care in general practice: 2-year follow-up study ⬇️

scientific article published on 01 November 1997

Symptoms and well-being in relation to glycemic control in type II diabetes

scientific article published in March 1996

Symptoms of depression in people with impaired glucose metabolism or Type 2 diabetes mellitus: The Hoorn Study

scientific article published in July 2008

Systemic inflammation is linked to low arginine and high ADMA plasma levels resulting in an unfavourable NOS substrate-to-inhibitor ratio: the Hoorn Study

scientific article published in July 2011

Ten-year time course of risk factors for increased carotid intima-media thickness: the Hoorn Study

scientific article published in April 2010

The 12-item well-being questionnaire. An evaluation of its validity and reliability in Dutch people with diabetes

scientific article published in December 1999

The 1997 American Diabetes Association criteria versus the 1985 World Health Organization criteria for the diagnosis of abnormal glucose tolerance: poor agreement in the Hoorn Study

scientific article published in October 1998

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

scientific article published on 14 May 2013

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases

scientific article

The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations

scientific article

The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study

scientific article published in November 2006

The Medi-Jector II: efficacy and acceptability in insulin-dependent diabetic patients with and without needle phobia

scientific article published on 01 March 1988

The absorption kinetics of subcutaneously infused U 40 and U 100 insulin in diabetics

scientific article published on 01 July 1987

The assessment of diabetic polyneuropathy in daily clinical practice: reproducibility and validity of Semmes Weinstein monofilaments examination and clinical neurological examination

scientific article published on 01 January 1997

The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies

scientific article published in February 2010

The association of dietary fibres with glucose tolerance is partly explained by concomitant intake of thiamine: the Hoorn Study

scientific article

The diabetic diet: no different from nutrition for healthy persons

scientific article published on 01 August 1984

The distribution of peripheral vascular disease in a Dutch Caucasian population: comparison of type II diabetic and non-diabetic subjects

scientific article

The effect of acute hyperglycemia on retinal thickness and ocular refraction in healthy subjects

scientific article published on 25 January 2008

The effect of angiotensin-I converting enzyme inhibition on insulin action in healthy volunteers

scientific article published on October 1991

The effect of dietary linoleic acid and pectin on lipoprotein and apolipoprotein A1 concentrations in rhesus monkeys

scientific article published in January 1984

The heritability of beta cell function parameters in a mixed meal test design

scientific article

The impact of dyslipidaemia on cardiovascular mortality in individuals without a prior history of diabetes in the DECODE Study

scientific article published on 23 February 2009

The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia

scientific article published on 8 September 2010

The oral glucose tolerance test (OGTT): effect of rate of ingestion of carbohydrate and different carbohydrate preparations

scientific article published on 01 September 1983

The pharmacodynamics and activity of intranasally administered insulin in healthy male volunteers

scientific article published on 01 November 1993

The practice guideline 'Pregnancy and puerperium' (first revision) from the Dutch College of General Practitioners

scientific article published in April 2004

The relationship between self-monitored blood glucose values and glycated haemoglobin in insulin-treated patients with Type 2 diabetes

scientific article published in May 2010

The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects

scientific article

The relationship of lipoprotein lipase activity and LDL size is dependent on glucose metabolism in an elderly population: the Hoorn Study

scientific article published in March 2004

The well-being questionnaire: evidence for a three-factor structure with 12 items (W-BQ12).

scientific article

Thiamine may indirectly act as an antioxidant

scientific article published on 01 June 1997

Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence

scientific article

Time to insulin initiation and long-term effects of initiating insulin in people with type 2 diabetes mellitus: the Hoorn Diabetes Care System Cohort Study

scientific article published on 2 February 2016

Triiodothyronine: a link between the insulin resistance syndrome and blood pressure?

scientific article

Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels: the Hoorn study

scientific article published in February 2004

Two prospective studies found that elevated 2-hr glucose predicted male mortality independent of fasting glucose and HbA1c

scientific article published in June 2004

Type 2 diabetes is associated with impaired endothelium-dependent, flow-mediated dilation, but impaired glucose metabolism is not; The Hoorn Study

scientific article

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps

scientific article published on 11 July 2008

Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.

scientific article published in March 2002

Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K(+) channel in the beta-cell

scientific article published in October 2002

Vitamin D and mortality in older men and women

scientific article published on 18 February 2009

Voxel-based morphometry demonstrates reduced grey matter density on brain MRI in patients with diabetic retinopathy

scientific article published on 16 May 2006

Well-Being and Symptoms in Relation to Insulin Therapy in Type 2 Diabetes ⬇️

scientific article published on June 1, 1998

What are the consequences of the new American guidelines for the diagnosis of diabetes mellitus in The Netherlands?

scientific article published in January 1998

Why is soluble intercellular adhesion molecule-1 related to cardiovascular mortality?

scientific article published in January 2002

von Willebrand Factor, C-Reactive Protein, and 5-Year Mortality in Diabetic and Nondiabetic Subjects

article

von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and nondiabetic subjects: the Hoorn Study

article by A Jager et al published December 1999 in Arteriosclerosis, Thrombosis, and Vascular Biology

Paulina is supported by:

About Paulina

Help