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List of works by Raymond Norton

13C n.m.r. spin–lattice relaxation time measurements determining the major tautomer of 1-methylisoguanosine in solution

19F NMR as a probe of ligand interactions with the iNOS binding site of SPRY domain-containing SOCS box protein 2.

scientific article published on 5 June 2014

1H, 13C and 15N resonance assignments of a highly-soluble murine interleukin-3 analogue with wild-type bioactivity

scientific article published on 20 February 2010

1H, 13C and 15N resonance assignments of the C-terminal domain of insulin-like growth factor binding protein-6 (IGFBP-6)

scientific article published on 01 March 2003

A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3

scientific article

A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent

scientific article published on 18 September 2018

A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin Fold

scientific article published on 2 February 2016

A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors

article

A disulfide-stabilised helical hairpin fold in acrorhagin I: an emerging structural motif in peptide toxins

scientific article published on 30 December 2020

A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides

scientific article

A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily

scientific article published on 7 March 2012

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

scientific article

A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin.

scientific article published on 6 October 2003

A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily.

scientific article

A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils

scientific article published in December 2007

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

scientific article

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

scientific article

A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent

scientific article published on 06 August 2014

A series of chiral polybrominated biindoles from the marine blue-green alga Rivularia firma. Application of carbon-13 NMR spin-lattice relaxation data and carbon-13-proton coupling constants to structure elucidation

scientific article published on 18 March 2005

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

scientific article published on 01 June 2020

Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes

scientific article published on 20 September 2006

Activation of Src family tyrosine kinases by ferric ions

scientific article

Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.

scientific article

Analogs of the Sea Anemone Potassium Channel Blocker ShK for the Treatment of Autoimmune Diseases

scientific article published on October 1, 2011

Anti-Infective Peptides to Enhance the Host Innate Response: Design, Development and Delivery

article

Antibody Recognition of Disordered Antigens

scientific article

Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2.

scientific article

Antimalarial drug discovery targeting apical membrane antigen 1

Antimicrobial activity and structure of a consensus human β-defensin and its comparison to a novel putative hBD10

scientific article published on 30 July 2019

Apical membrane antigen 1 as an anti-malarial drug target

scientific article published on January 2011

Applications of (19)F-NMR in Fragment-Based Drug Discovery

scientific article published in 2016

Assessing the cellular toxicity of peptide inhibitors of intracellular protein-protein interactions by microinjection

scientific article published on 03 December 2020

Assignment of 1H and 15N resonances of murine Tec SH3 domain.

scientific article

Assignment of 1H, 13C and 15N resonances of domain III of the ectodomain of apical membrane antigen 1 from Plasmodium falciparum

scientific article published on 01 January 2001

Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

scientific article published on 12 June 2020

Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections

scientific article

Binding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1

scientific article published in October 2005

Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions

scientific article published in June 2004

Biological activity and ferric ion binding of fragments of glycine-extended gastrin.

scientific article published on September 2004

Buccal mucosal delivery of a potent peptide leads to therapeutically-relevant plasma concentrations for the treatment of autoimmune diseases

article published in 2015

C-terminal domain of insulin-like growth factor (IGF) binding protein 6: conformational exchange and its correlation with IGF-II binding

scientific article published on 01 September 2004

C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II

scientific journal article

CHAPTER 10. Case Study 2: Transforming a Toxin into a Therapeutic: the Sea Anemone Potassium Channel Blocker ShK Toxin for Treatment of Autoimmune Diseases

Characterisation of a novel coumarin-based fluorescent probe for monitoring nitric oxide production in macrophages.

scientific article published on 5 September 2017

Characterisation of peptide interactions that regulate PKCε activation

scientific article published on 20 December 2017

Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context

scientific article published on 09 April 2020

Coarse-grained dynamics of the receiver domain of NtrC: fluctuations, correlations and implications for allosteric cooperativity.

scientific article published in October 2008

Computational approaches for designing potent and selective analogs of peptide toxins as novel therapeutics

scientific article

Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2

scientific article

Conformational exchange in the potassium channel blocker ShK

scientific article published on 17 December 2019

Conformational flexibility in the binding surface of the potassium channel blocker ShK.

scientific article

Conotoxin gene superfamilies

scientific article

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity

scientific article published in April 2007

Conotoxins down under

scientific article published on 15 July 2006

Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.

scientific article published in October 2004

Cooperativity of the N- and C-terminal domains of insulin-like growth factor (IGF) binding protein 2 in IGF binding

scientific article

Correction to: NMR in pharmaceutical discovery and development

scientific article published on 13 November 2020

Correlations among sequence, physicochemical properties and function in peptide toxins

scientific article published on 01 April 2020

Corrigendum to "Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK" [Peptides 99 (2018) 169-178].

scientific article published on 17 January 2018

De novo design and synthesis of a μ-conotoxin KIIIA peptidomimetic

scientific article published on 06 July 2013

Defining the interaction of perforin with calcium and the phospholipid membrane

scientific article

Design and synthesis of type-III mimetics of ShK toxin.

scientific article published in April 2002

Design and synthesis of type-III mimetics of omega-conotoxin GVIA

scientific article published on 01 December 2001

Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB

scientific article published on 23 May 2016

Designed Peptide Analogues of the Potassium Channel Blocker ShK Toxin

scientific article published on December 25, 2001

Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

article

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

scientific article

Development of highly selective Kv1.3-blocking peptides based on the sea anemone peptide ShK.

scientific article

Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets

scientific article

Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors

scientific article

Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom

scientific article

Disordered epitopes as peptide vaccines

scientific article published on 14 April 2018

Distinct Disulfide Isomers of μ-Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium Channels

scientific article

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

scientific article published on 16 June 2017

Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae

scientific article (publication date: 2014)

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

scientific article published on 03 August 2013

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops

scientific article

EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2

scientific article

Editorial: Special issue of Biophysical Reviews dedicated to the joint 10th Asian Biophysics Association Symposium and 42nd Australian Society for Biophysics Meeting, Melbourne, Australia, December 2-6, 2018.

scientific article

Effect of lipid on the conformation of the N-terminal region of equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study

scientific article

Effects of the eukaryotic pore-forming cytolysin Equinatoxin II on lipid membranes and the role of sphingomyelin

scientific article published on April 2003

Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function?

scientific article published on 19 April 2011

Enabling Noninvasive Systemic Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] via the Buccal Mucosa

scientific article published on 13 June 2016

Enhancing the buccal mucosal delivery of peptide and protein therapeutics.

scientific article

Enhancing the therapeutic potential of peptide toxins

scientific article published on 11 April 2017

Evolution of cnidarian trans-defensins: sequence, structure and exploration of chemical space

scientific article published on 27 February 2019

Exchange enhanced sensitivity gain for solvent-exchangeable protons in 2D 1H-15N heteronuclear correlation spectra acquired with band-selective pulses

scientific article

Expression and isotopic labelling of the potassium channel blocker ShK toxin as a thioredoxin fusion protein in bacteria

scientific article

Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin.

scientific article published on 20 September 2002

Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family

Hormone-like peptides in the venoms of marine cone snails

scientific article published on 21 August 2015

IGF-binding proteins--the pieces are falling into place.

scientific article

Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2)

scientific article

Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe

scientific article published on 13 February 2019

Identification, chemical synthesis, structure, and function of a new KV 1 channel blocking peptide from Oulactis sp

scientific article published on 24 May 2018

Immunology: Channelling potassium to fight cancer

scientific article published on 14 September 2016

Improving membrane permeation in the beyond rule-of-five space by using prodrugs to mask hydrogen bond donors

scientific article published on 06 July 2020

Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2.

scientific article published in July 2010

Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.

scientific article

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain

scientific article published on 22 September 2011

Insulin-like growth factor binding proteins: a structural perspective

scientific article

Insulin-like growth factor-I (IGF-I): solution properties and NMR chemical shift assignments near physiological pH.

scientific article published on 3 December 2008

Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites

scientific article

Interaction of merozoite surface protein 2 with lipid membranes

scientific article published on 10 January 2019

Interaction of the eukaryotic pore-forming cytolysin equinatoxin II with model membranes: 19F NMR studies

scientific article published on 18 January 2005

Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.

scientific article

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

scientific article published on 08 February 2022

Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease

scientific article published on 8 January 2013

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

scientific article

Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA

scientific article published on 12 October 2011

Large-scale prediction of long disordered regions in proteins using random forests

scientific article

Letter to the Editor: Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2)

scientific article published in January 2005

Ligand-induced conformational change of Plasmodium falciparum AMA1 detected using 19F NMR.

scientific article published on 5 August 2014

Lipid interactions modulate the structural and antigenic properties of the C-terminal domain of the malaria antigen merozoite surface protein 2.

scientific article published on 15 June 2017

Lipid interactions of the malaria antigen merozoite surface protein 2.

scientific article

Mammalian Neuronal Sodium Channel Blocker μ-Conotoxin BuIIIB Has a Structured N-Terminus That Influences Potency

scientific article

Mapping the chemical and sequence space of the ShKT superfamily

scientific article published on 04 May 2019

Merozoite Surface Protein 2 Adsorbed onto Acetalated Dextran Microparticles for Malaria Vaccination

scientific article published on 09 December 2020

Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics, and fibril formation of the conserved N-terminal domain.

scientific article published in September 2007

Mimotopes of apical membrane antigen 1: Structures of phage-derived peptides recognized by the inhibitory monoclonal antibody 4G2dc1 and design of a more active analogue

scientific article

Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin

scientific article published on 14 May 2020

Modulation of the aggregation of an amyloidogenic sequence by flanking-disordered region in the intrinsically disordered antigen merozoite surface protein 2

scientific article published on 15 November 2018

Molecular Insights into the Interaction Between the SPRY Domain-Containing SOCS Box Protein SPSB2 and Peptides Based on the Binding Motif from iNOS

Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

scientific article

Mu-conotoxins as leads in the development of new analgesics

scientific article published on 19 April 2010

Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution

scientific article

Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3.

scientific article

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

scientific article published on 23 April 2015

NMR in pharmaceutical discovery and development

scientific article published on 04 September 2020

NMR spectroscopy of peptides and proteins.

scientific article

Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation.

scientific article published on 16 December 2015

Novel Conotoxins fromConus striatusandConus kinoshitaiSelectively Block TTX-Resistant Sodium Channels

scientific article published in 2006

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels

scientific article published in May 2005

OR04-3 C-TERMINAL DOMAIN OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 (IGFBP-2): STRUCTURE, DYNAMICS AND INTERACTION WITH IGFS

Peptide blockers of Kv1.3 channels in T cells as therapeutics for autoimmune disease

scientific article

Peptide inhibitors of the malaria surface protein, apical membrane antigen 1: identification of key binding residues

scientific article

Peptide self-association in aqueous trifluoroethanol monitored by pulsed field gradient NMR diffusion measurements.

scientific article

Peptide therapeutics from venom: Current status and potential.

scientific article published on 23 September 2017

Peptides targeting voltage-gated calcium channels.

scientific article published on January 2008

Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

scientific article published on 23 July 2011

Polybrominated oxydiphenol derivatives from the sponge dysidea herbacea

scientific article published on 25 July 2002

Potassium channel blockade by the sea anemone toxin ShK for the treatment of multiple sclerosis and other autoimmune diseases

scientific article

Potassium channel gating: not an open and shut case

scientific article

Potassium channel modulation by a toxin domain in matrix metalloprotease 23

scientific article

Predicting disordered regions in proteins based on decision trees of reduced amino acid composition.

scientific article

Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond

scientific article published in Journal of Biological Chemistry

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

scientific article published on 4 April 2017

Prolonged plasma exposure of the Kv1.3-inhibitory peptide HsTX1[R14A] by subcutaneous administration of a poly(lactic-co-glycolic acid) (PLGA) microsphere formulation

scientific article published on 13 October 2020

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

scientific article published on 16 January 2015

Protein effective rotational correlation times from translational self-diffusion coefficients measured by PFG-NMR

scientific article published on 14 June 2008

Pulmonary Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] for the Treatment of Autoimmune Diseases.

scientific article published on 12 January 2016

Purification and characterization of ciguatoxins from moray eel (Lycodontis javanicus, Muraenidae)

scientific article published on January 1, 1991

RASP: rapid and robust backbone chemical shift assignments from protein structure.

scientific article

Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning

scientific article published on 21 January 2009

Recombinant protein vaccines against the asexual blood stages of Plasmodium falciparum

scientific article published on 19 January 2010

Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction

scientific article

Regulation of a Potassium Channel by the Pro-Domain of a Matrix Metalloprotease

Reinvestigation of the biological activity of d-allo-ShK protein

scientific article published on 8 June 2017

Role of the helical structure of the N-terminal region of Plasmodium falciparum merozoite surface protein 2 in fibril formation and membrane interaction

scientific article published on 8 February 2012

SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding

scientific article

Sea Anemones: Quiet Achievers in the Field of Peptide Toxins

scientific article published on 8 January 2018

Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain

scientific journal article

Solid-state NMR and simulation studies of equinatoxin II N-terminus interaction with lipid bilayers

scientific article

Solid-state NMR study of membrane interactions of the pore-forming cytolysin, equinatoxin II.

scientific article published on 24 October 2009

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials

scientific article published on 24 January 2016

Solution Structure of Leukemia Inhibitory Factor

scientific article published on May 29, 1998

Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2.

scientific article published on 28 March 2008

Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels

scientific article

Solution structure of robustoxin, the lethal neurotoxin from the funnel‐web spider Atrax robustus

scientific article published on December 15, 1997

Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation

scientific article

Specialized insulin is used for chemical warfare by fish-hunting cone snails.

scientific article

Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.

scientific article published on 06 April 2008

Stabilization of the helical structure of Y2-selective analogues of neuropeptide Y by lactam bridges

scientific article

Stereoselective synthesis and structural elucidation of dicarba peptides

scientific article published on 01 March 2016

Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2.

scientific article published on 11 February 2016

Strategies for the development of conotoxins as new therapeutic leads

scientific article published on 28 June 2013

Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes

scientific article

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ.

scientific article published on 27 January 2016

Structural Dynamics of the Potassium Channel Blocker ShK: SRLS Analysis of (15)N Relaxation

scientific article published on 9 November 2015

Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa

scientific article published on 11 July 2019

Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development

scientific article published on 2 December 2004

Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4

scientific article

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

scientific article published on 12 May 2015

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA

scientific article

Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11

scientific article

Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.

scientific article published on 8 February 2017

Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5

scientific article

Structure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡

scientific article

Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue

scientific article published in February 2009

Structure and activity of D-Pro14 melittin

scientific article

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

scientific article published on 16 February 2017

Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II.

scientific article

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO

scientific article

Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity

scientific article published on January 2013

Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity

scientific article

Structure and inter-domain interactions of domain II from the blood-stage malarial protein, apical membrane antigen 1.

scientific article published in July 2005

Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif

scientific article

Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1)

scientific article

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

scientific article (publication date: 9 May 2003)

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion

scientific article

Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)

scientific article

Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

scientific article

Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.

scientific article published on 6 October 2017

Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the Campylobacter jejuni Chemoreceptor Tlp3

scientific article published on 11 May 2020

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction

scientific article

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

scientific article published on 27 August 2007

Structures of phage-display peptides that bind to the malarial surface protein, apical membrane antigen 1, and block erythrocyte invasion.

scientific article

Structures of sea anemone toxins

scientific article published on 13 March 2009

Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity

scientific article published in February 2012

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

scientific article

Synthesis and characterization of delta-atracotoxin-Ar1a, the lethal neurotoxin from venom of the Sydney funnel-web spider (Atrax robustus).

scientific article published on November 2003

Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold

scientific article published on 19 May 2018

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

scientific article

Tentacle Transcriptomes of the Speckled Anemone (Actiniaria: Actiniidae: Oulactis sp.): Venom-Related Components and Their Domain Structure

scientific article published on 24 January 2020

The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation

scientific article

The N-terminal domains of SOCS proteins: a conserved region in the disordered N-termini of SOCS4 and 5.

scientific article published in March 2012

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs

scientific article

The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase

scientific article

The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression

scientific article published on March 2009

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues

scientific article published on 20 December 2005

The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

scientific article

The Single Disulfide-Directed β-Hairpin Fold. Dynamics, Stability, and Engineering

scientific article published on 24 April 2017

The Use of Imaging Mass Spectrometry to Study Peptide Toxin Distribution in Australian Sea Anemones

scientific article published in 2017

The cystine knot structure of ion channel toxins and related polypeptides

scientific article published on 01 November 1998

The effects of lipids on the structure of the eukaryotic cytolysin equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study

scientific article published on 8 April 2008

The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

scientific article published on April 2006

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

scientific article published on 11 April 2019

The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

scientific article published on January 2009

The voltage-gated potassium channel KV1.3 as a therapeutic target for venom-derived peptides

scientific article published on 09 July 2020

The ways and means of fragment-based drug design

scientific article

Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope

scholarly article published 2018

Tyrosine modification enhances metal-ion binding

scientific article published on November 2008

Venom-derived peptide inhibitors of voltage-gated potassium channels

scientific article published on 5 July 2017

Venoms to the rescue

scientific article

X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors

scientific article published on 09 May 2017

α-Conotoxin Peptidomimetics: Probing the Minimal Binding Motif for Effective Analgesia

scientific article published on 06 August 2020

α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding Residues

scientific article