List of works by Minoru Fujimoto

Aberrant expression of glycosylation in juvenile gastrointestinal stromal tumors

scientific article published on 21 July 2008

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner

scientific article

Annexin A4-conferred platinum resistance is mediated by the copper transporter ATP7A.

scientific article published on 21 October 2013

Anti-glypican-1 antibody-drug conjugate exhibits potent preclinical antitumor activity against glypican-1 positive uterine cervical cancer

scientific article

Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer

scientific article published on 10 March 2020

Antiproliferative effect of SOCS-1 through the suppression of STAT3 and p38 MAPK activation in gastric cancer cells.

scientific article

Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma

scientific article published on 07 November 2011

Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses

scientific article published on 24 April 2010

Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis

scientific article published on 17 May 2011

Brief Report: Leucine-Rich α2-Glycoprotein as a Potential Biomarker for Joint Inflammation During Anti-Interleukin-6 Biologic Therapy in Rheumatoid Arthritis

scientific article published on 01 May 2015

CTLA4-Ig suppresses development of experimental autoimmune uveitis in the induction and effector phases: Comparison with blockade of interleukin-6

scientific article published on 20 August 2015

Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling

scientific article published on 18 February 2016

Comparative analysis of the effects of anti-IL-6 receptor mAb and anti-TNF mAb treatment on CD4+ T-cell responses in murine colitis

scientific article published on 01 February 2011

CpG oligodeoxynucleotides potentiate the antitumor activity of anti-BST2 antibody

scientific article

Dysregulation of melanocyte function by Th17-related cytokines: significance of Th17 cell infiltration in autoimmune vitiligo vulgaris

scientific article published on 10 February 2012

Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin

scientific article published in November 2009

Epithelial-mesenchymal transition via transforming growth factor beta in pancreatic cancer is potentiated by the inflammatory glycoprotein leucine-rich alpha-2 glycoprotein

scientific article published on 04 February 2019

Evaluation of leucine-rich alpha-2 glycoprotein as a biomarker of fetal infection

scientific article published on 19 November 2020

Flavonoids such as luteolin, fisetin and apigenin are inhibitors of interleukin-4 and interleukin-13 production by activated human basophils.

scientific article

Gene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis.

scientific article published on 16 July 2015

Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma

scientific article

Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression.

scientific article published on 26 February 2010

Histamine contributes to tissue remodeling via periostin expression.

scientific article published on 27 February 2014

IL-18 gene polymorphisms affect IL-18 production capability by monocytes

scientific article published on 28 February 2006

Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases

scientific article published on 01 February 2004

Increased serum CXCR2 ligand levels in livedo vasculopathy with winter ulcerations: Possible contribution of neutrophil recruitment to lesional skin.

scientific article published on 8 January 2016

Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation

scientific article

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

scientific article published on 01 December 2008

Intratumoral delivery of an adenoviral vector carrying the SOCS-1 gene enhances T cell-mediated anti-tumor immunity by suppressing PD-L1.

scientific article

LSR Antibody Therapy Inhibits Ovarian Epithelial Tumor Growth by Inhibiting Lipid Uptake.

scientific article published on 29 November 2017

Leucine rich α-2 glycoprotein is a potential urinary biomarker for renal tubular injury.

scientific article published on 15 March 2018

Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.

scientific article published on 27 July 2016

Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells.

scientific article

Leucine-rich α-2 glycoprotein is an innovative biomarker for psoriasis.

scientific article published on 29 January 2017

Leucine-rich α-2 glycoprotein promotes lung fibrosis by modulating TGF-β signaling in fibroblasts

scientific article published on 26 December 2017

Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines

scientific article published on May 2015

Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer

Luteolin, a flavonoid, inhibits CD40 ligand expression by activated human basophils.

scientific article published on 4 April 2006

Molecular mechanism underlying the antiproliferative effect of suppressor of cytokine signaling-1 in non-small-cell lung cancer cells.

scientific article published on 19 September 2013

Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction.

scientific article published on 17 December 2015

NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation

scientific article published on 22 June 2018

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: programmed endosomal escape and dissociation

scientific article published on 15 January 2010

New findings of kinase switching in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis.

scientific article published on 14 June 2013

Osteoblast differentiation is impaired in SOCS-1-deficient mice.

scientific article published in January 2006

Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma

scientific article published on 2 December 2010

Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma.

scientific article published on 16 June 2016

Periostin accelerates human malignant melanoma progression by modifying the melanoma microenvironment

scientific article published on 22 April 2014

Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma.

scientific article

Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts.

scientific article published in May 2012

Plasma membrane proteomics identifies bone marrow stromal antigen 2 as a potential therapeutic target in endometrial cancer.

scientific article

Proteomic analysis of autoantigens associated with systemic lupus erythematosus: Anti-aldolase A antibody as a potential marker of lupus nephritis

scientific article published on 22 January 2007

Proteomics-based identification of alpha-enolase as a tumor antigen in non-small lung cancer.

scientific article published on 15 May 2007

Regulation of cytokine signaling by SOCS family molecules

scientific article

Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation

scientific article published on 09 September 2010

SOCS-1 participates in negative regulation of LPS responses

scientific article published on 01 November 2002

SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells.

scientific article published on May 2006

SOCS1 Gene Therapy Improves Radiosensitivity and Enhances Irradiation-Induced DNA Damage in Esophageal Squamous Cell Carcinoma

scientific article published on 17 October 2017

SOCS1 gene therapy has antitumor effects in imatinib-resistant gastrointestinal stromal tumor cells through FAK/PI3 K signaling.

scientific article published on 5 April 2018

SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases.

scientific article

Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice

scientific article

Similar protein expression profiles of ovarian and endometrial high-grade serous carcinomas.

scientific article published on 18 February 2016

Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma

scientific article

Suppressor of cytokine signaling 1 suppresses muscle differentiation through modulation of IGF-I receptor signal transduction.

scientific article published on March 2005

Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice

scientific article published on 01 April 2008

Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice

scientific article published on 24 February 2017

Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines

scientific article published on September 2004

Suppressor of cytokine signalling-1 induces significant preclinical antitumor effect in malignant melanoma cells.

scientific article published on 14 July 2015

TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours

scientific article published on 20 December 2019

The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells

scientific article published on 24 November 2010

[Role of IL-6 in the development and pathogenesis of CIA and EAE]

scientific article published on 01 April 2008

iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases

scientific article published on 22 October 2009

ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury

scientific article published on 04 July 2013

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