Search filters

List of works by Arrigo De Benedetti

A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells ⬇️

scientific article published on October 28, 2003

A novel BK virus-based episomal vector for expression of foreign genes in mammalian cells ⬇️

scientific article published on April 25, 1991

Antisense RNA to eIF4E suppresses oncogenic properties of a head and neck squamous cell carcinoma cell line.

scientific article

Clinical Outcome in Stage I to III Breast Carcinoma and eIF4E Overexpression ⬇️

scientific article published on May 1, 1998

Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts.

scientific article published on November 1993

Detection of eIF4E gene amplification in breast cancer by competitive PCR.

scientific article published in April 1998

Detection of the Proto-oncogene eIF4E in Larynx and Hypopharynx Cancers

scientific article published on 01 February 1999

Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer

scientific article published on 01 July 1997

Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E ⬇️

scientific article published on June 1, 1998

Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas

scientific article published on 01 August 1997

Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing.

scientific article

Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation

scientific article

Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.

scientific article published on 20 April 2017

Inhibition of mRNA binding to ribosomes by localized activation of dsRNA-dependent protein kinase ⬇️

scientific article published on September 6, 1984

NEK1 Phosphorylation of YAP Promotes Its Stabilization and Transcriptional Output

scientific article published on 07 December 2020

Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS.

scientific article

Overexpression of eIF4E in Saccharomyces cerevisiae causes slow growth and decreased alpha-factor response through alterations in CLN3 expression

scientific article published on 30 July 2001

Overexpression of the proto-oncogene/translation factor 4E in breast-carcinoma cell lines

scientific article published on 01 March 1996

Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy

scientific article

Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin

scientific article

Progressive amplification and overexpression of the eukaryotic initiation factor 4E gene in different zones of head and neck cancers

article

Selective killing of cancer cells based on translational control of a suicide gene.

scientific article published in July 2002

TAT-mediated delivery of Tousled protein to salivary glands protects against radiation-induced hypofunction

scientific article published on 26 January 2012

TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.

scientific article

TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1

scientific article

Targeting and killing of prostate cancer cells using lentiviral constructs containing a sequence recognized by translation factor eIF4E and a prostate-specific promoter.

scientific article

Targeting the TLK1/NEK1 DDR axis with Thioridazine suppresses outgrowth of androgen independent prostate tumors

scientific article published on 25 February 2019

The Tousled-Like Kinases as Guardians of Genome Integrity ⬇️

scientific article published on January 1, 2012

The expression of tousled kinases in CaP cell lines and its relation to radiation response and DSB repair ⬇️

scientific article published on February 14, 2011

The proto-oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas

scientific article published on 01 February 1995

Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

scientific article published on 24 April 2009

Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair.

scientific article

Tousled kinase TLK1B counteracts the effect of Asf1 in inhibition of histone H3-H4 tetramer formation

scientific article published on 8 July 2009

Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity

scientific article

Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cells

scientific article published on 5 February 2016

Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1

scientific article

Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis

scientific article published on 01 March 1996

Up-regulation of TLK1B by eIF4E overexpression predicts cancer recurrence in irradiated patients with breast cancer

scientific article published on 01 August 2006

eIF-4E expression and its role in malignancies and metastases.

scientific article published on April 2004

eIF4E as a marker for cervical neoplasia

scientific article published on 01 December 2005

Paulina is supported by:

About Paulina

Help