Search filters

List of works by Alessandra Silvani

1,3-Dioxolan-4-Ones as Promising Monomers for Aliphatic Polyesters: Metal-Free, in Bulk Preparation of PLA

scientific article published on 18 October 2020

A new spirocyclic proline-based lactam as efficient type II′ β-turn inducing peptidomimetic

Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin

scientific article published on June 17, 2011

An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions

scientific article published on 01 April 2006

Application of the Ugi reaction with multiple amino acid-derived components: synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics.

scientific article

Aspidosperma alkaloids cyclization of secodine intermediate: Synthesis of (±)-3-oxovincadifformine ethyl ester

Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives.

scientific article published on 18 June 2014

Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.

scientific article published on 20 January 2015

Cannabinoid-free Cannabis sativa L. grown in the Po valley: evaluation of fatty acid profile, antioxidant capacity and metabolic content

scientific article published on 17 June 2014

Chemical approaches to targeting drug resistance in cancer stem cells.

scientific article published on 10 May 2014

Combinatorial solid-phase synthesis of 6-hydroxy-1,2,3,4-tetrahydro-beta-carbolines from l-5-hydroxytryptophan.

scientific article

Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues

scientific article published on 15 October 2015

Computationally Driven Structure Optimization, Synthesis, and Biological Evaluation of Imidazole-Based Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibitors

scientific article published on 01 July 2019

Concise total synthesis of (+/-)-aloperine and 6-epi-aloperine

scientific article published on 01 August 2002

Disrupting the PCSK9/LDLR protein-protein interaction by an imidazole-based minimalist peptidomimetic

scientific article

Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance

scientific article published on 13 August 2020

Grignard addition to imines derived from isatine: a method for the asymmetric synthesis of quaternary 3-aminooxindoles.

scientific article published on June 2009

Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation

scientific article

Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance

scientific article published on 17 April 2018

Highly diastereoselective entry into chiral spirooxindole-based 4-methyleneazetidines via formal [2+2] annulation reaction

scientific article published on 07 September 2016

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes

scientific article published on 01 March 2003

Microwave-assisted, solid-phase synthesis of a chiral 1,2,3,4-tetrahydro-quinoline library.

scientific article

Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library

scientific article published on 23 June 2015

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

scientific article published on 30 August 2011

Natural Products and Cancer Stem Cells.

scientific article published on 02 October 2015

Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine

scientific article published on 01 July 2006

New class of squalene-based releasable nanoassemblies of paclitaxel, podophyllotoxin, camptothecin and epothilone A.

scientific article

Olefin metathesis based approach to diversely functionalized pyrrolizidines and indolizidines; total synthesis of (+)-monomorine.

scientific article

One step access to oxindole-based β-lactams through Ugi four-center three-component reaction

scholarly article in RSC Advances, vol. 8 no. 61, 2018

Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines.

scientific article published on 21 November 2017

Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin.

scientific article published on 2 February 2016

Organocatalytic vinylogous Mannich reaction of trimethylsiloxyfuran with isatin-derived benzhydryl-ketimines.

scientific article published on 29 July 2016

Phe-Ala-based diazaspirocyclic lactam as nucleator of type II' β-turn

scientific article published on 11 January 2011

Photochemical Isomerization of Colchicine and Thiocolchicine

Phytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities

scientific article published on 17 October 2018

Pyrroloisoquinoline-based tetrapeptide analogues mimicking reverse-turn secondary structures

scientific article published on 09 November 2007

Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins

scientific article published on 19 September 2013

Remote stereocenter discrimination in the enzymatic resolution of piperidine-2-ethanol. Short enantioselective synthesis of sedamine and allosedamine.

scientific article published in November 2003

Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalized Spirooxindole-Fused Thiazolidines.

scientific article

Structural and biological exploration of phe(3)-phe(4)-modified endomorphin-2 peptidomimetics

scientific article

Synthesis and biological evaluation of paclitaxel-thiocolchicine hybrids

scientific article published on February 2004

Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues

scholarly article by Giordano Lesma et al published 4 November 2012 in Molecular Diversity

Tetrahydro-β-carboline-based spirocyclic lactam as type II' β-turn: application to the synthesis and biological evaluation of somatostatine mimetics.

scientific article published on 21 February 2013

The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure.

scientific article published on 22 January 2013

Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction.

scientific article published in March 2006

Total enantioselective synthesis of (-)-cytisine

scientific article published on 01 February 2004

Ugi 4-CR/Pictet-Spengler reaction as a short route to tryptophan-derived peptidomimetics

scientific article published on 16 October 2012

trans-6-Aminocyclohept-3-enols, a new designed polyfunctionalized chiral building block for the asymmetric synthesis of 2-substituted-4-hydroxypiperidines

scientific article published on 01 April 2002