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List of works by Ludovic Vallier

3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo

scientific article published on 28 August 2018

A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei

scientific article published on 20 May 2020

A factor(s) secreted from MIN-6 beta-cells stimulates differentiation of definitive endoderm enriched embryonic stem cells towards a pancreatic lineage

scientific article published on 30 July 2010

A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance

scientific article published on 16 July 2018

A novel human pluripotent stem cell-derived neural crest model of Treacher Collins Syndrome shows defects in cell death and migration

article

A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells

scientific article

A proteomic time course through the differentiation of human induced pluripotent stem cells into hepatocyte-like cells

scientific article published on 01 March 2019

Activin/Nodal Signaling and Pluripotency

scientific article published on January 1, 2011

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

scientific article

Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors

scientific article

Activin/Nodal signalling in stem cells.

scientific article

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.

scientific article published on 11 March 2009

Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark.

scientific article

Advances in the generation of bioengineered bile ducts

scientific article published on 30 October 2017

Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae.

scientific article

Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells

scientific article

Cell Cycle Rules Pluripotency.

scientific article published in August 2015

Cell cycle regulators control mesoderm specification in human pluripotent stem cells

Cell cycle regulators control mesoderm specification in human pluripotent stem cells

scientific article published on 12 September 2019

Characterization of the Caenorhabditis elegans Islet LIM-homeodomain ortholog, lim-7.

scientific article published on 29 December 2008

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

scientific article published on 13 July 2015

Combined single cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

Common genetic variation drives molecular heterogeneity in human iPSCs

scientific article published on 10 May 2017

Common genetic variation drives molecular heterogeneity in human iPSCs

Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA.

scientific article published on 28 February 2018

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs

scientific article published in Nature

Culture of hESC-derived pancreatic progenitors in alginate-based scaffolds.

scientific article published on 25 May 2015

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.

scientific article

Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.

scientific article published on 8 January 2018

Derivation of Intestinal Organoids from Human Induced Pluripotent Stem Cells for Use as an Infection System.

scientific article published on 31 August 2016

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells

scientific article

Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways

scientific article

Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.

scientific article

Embryonic stem cell therapy for diabetes mellitus

scientific article published on 11 September 2007

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells

scientific article

Emerging use of stem cells in regenerative medicine.

scientific article published on 28 April 2010

Enhancing and diminishing gene function in human embryonic stem cells.

scientific article published on January 2004

Erratum: Genome editing reveals a role for OCT4 in human embryogenesis

scientific article published on 4 October 2017

Expression of the SUC2 gene of Saccharomyces cerevisiae is induced by low levels of glucose

scientific article published on 01 February 1997

Fucci2a mouse upgrades live cell cycle imaging.

scientific article published on January 2015

Generation of Distal Airway Epithelium from Multipotent Human Foregut Stem Cells

scientific article published on 15 April 2015

Generation of Hepatocytes from Pluripotent Stem Cells for Drug Screening and Developmental Modeling

scientific article published in January 2015

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Mononuclear Cells Using Sendai Virus.

scientific article published on 17 February 2015

Generation of functional hepatocytes by forward programming with nuclear receptors

scientific article published in 2022

Generation of multipotent foregut stem cells from human pluripotent stem cells

scientific article published on 10 October 2013

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

scientific article published on 4 August 2017

Genetic background drives transcriptional variation in human induced pluripotent stem cells

scientific article

Genome editing reveals a role for OCT4 in human embryogenesis

scientific article

Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells

scientific article (publication date: 2012)

HOXB4 overexpression promotes hematopoietic development by human embryonic stem cells.

scientific article published on 12 January 2006

Heps with pep: direct reprogramming into human hepatocytes

scientific article published on 01 March 2014

Human Pluripotent Stem Cell-Derived Endoderm for Modeling Development and Clinical Applications.

scientific article published in April 2018

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

scientific article

Human pluripotent stem cells for modelling human liver diseases and cell therapy

scientific article

Human stem cells for craniomaxillofacial reconstruction.

scientific article

Induced pluripotent stem cells--alchemist's tale or clinical reality?

scientific article published on 13 August 2010

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

scientific article

Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm

scientific article published on 11 October 2007

Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells

scientific article

Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D

scientific article published on February 2016

Integration-deficient lentivectors: an effective strategy to purify and differentiate human embryonic stem cell-derived hepatic progenitors.

scientific article

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.

scientific article

Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis

scientific article

International coordination of large-scale human induced pluripotent stem cell initiatives: Wellcome Trust and ISSCR workshops white paper

scientific article published on December 2014

Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions

scientific article published on 17 January 2014

Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue

scientific article published on 20 May 2019

Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos.

scientific article published on 16 October 2017

Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture

scientific article (publication date: 2014)

Microparticles and Fibrinolysis

scientific article published on 6 December 2016

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

scientific article

Molecular analysis of the SNF8 gene of Saccharomyces cerevisiae.

scientific article

Molecular and genetic analysis of the SNF7 gene in Saccharomyces cerevisiae

scientific article

Mouse pluripotent stem cells at a glance

scientific article published on 01 November 2011

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures

scientific article

Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells

scientific article

Navigating the pathway from embryonic stem cells to beta cells.

scientific article published on June 2004

New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae

scientific article

New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme.

scientific article

Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.

scientific article

Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells

scientific article

Nuclear transfer-derived epiblast stem cells are transcriptionally and epigenetically distinguishable from their fertilized-derived counterparts.

scientific article

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs.

scientific article published on December 2016

Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas

scientific article

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes. ⬇️

scientific article

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

scientific article

Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells

scientific article published on 06 September 2007

Potential of human induced pluripotent stem cells in studies of liver disease

scientific article

Production of hepatocyte-like cells from human pluripotent stem cells.

scientific article published on February 2013

Proteomic comparison of various hepatic cell cultures for preclinical safety pharmacology.

scientific article published on 4 April 2018

Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

scientific article published on 23 March 2020

Putting induced pluripotent stem cells to the test

scientific article published on 01 November 2015

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.

scientific article

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

scientific article

Regional differences in human biliary tissues and corresponding in vitro derived organoids

scientific article published on 29 March 2020

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells

scientific article published on 01 August 2018

Robust differentiation of fetal hepatocytes from human embryonic stem cells and iPS

scientific article published in December 2010

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

scientific article published in January 2010

Science-based assessment of source materials for cell-based medicines: report of a stakeholders workshop

scientific article published on 29 November 2018

Senescence impairs successful reprogramming to pluripotent stem cells

scientific article

Serum-free and feeder-free culture conditions for human embryonic stem cells

scientific article published on 01 January 2011

Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.

scientific article

Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

scientific article published on 10 February 2020

Single-cell atlas of human liver development reveals pathways directing hepatic cell fates

scientific article published on 15 September 2022

Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr.

scientific article

Survival and differentiation of adenovirus-generated induced pluripotent stem cells transplanted into the rat striatum

scientific article published on 22 July 2013

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

scientific article published on 27 April 2015

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

scientific article

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

scientific article

The DSL ligand APX-1 is required for normal ovulation in C. elegans

scientific article published on 22 January 2018

The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency

scientific article published on 28 February 2018

The alpha-factor receptor C-terminus is important for mating projection formation and orientation in Saccharomyces cerevisiae.

scientific article

The cell-cycle state of stem cells determines cell fate propensity.

scientific article published on September 2013

The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages.

scientific article published on 17 October 2016

The role of hepatocyte nuclear factor 1β in disease and development.

scientific article published on September 2016

The serpinopathies studying serpin polymerization in vivo

scientific article

The spa2-related protein, sph1p, is important for polarized growth in yeast ⬇️

scientific article published on February 1, 1998

Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury

scientific article published on 17 October 2013

Use of Biliary Organoids in Cholestasis Research

scientific article published on 01 January 2019

Variability of human pluripotent stem cell lines.

scientific article

hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency.

scientific article published on 5 June 2018

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