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List of works by Evelien Smits

Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients

scientific article published on 21 September 2017

Acute myeloid leukemic cell lines loaded with synthetic dsRNA trigger IFN-gamma secretion by human NK cells.

scientific article published on 9 October 2008

Altered CD4 T cell immunity in nurses occupationally exposed to viral pathogens

scientific article published on 19 September 2018

Anti-cancer capacity of plasma-treated PBS: effect of chemical composition on cancer cell cytotoxicity

scientific article

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis.

scientific article published on 22 October 2015

BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target?

scientific article published on 19 September 2018

Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials.

scientific article

Building a Bridge between Chemotherapy and Immunotherapy in Malignant Pleural Mesothelioma: Investigating the Effect of Chemotherapy on Immune Checkpoint Expression ⬇️

scientific article published on 26 August 2019

CD56 Homodimerization and Participation in Anti-Tumor Immune Effector Cell Functioning: A Role for Interleukin-15

scientific article published on 22 July 2019

CD56 in the Immune System: More Than a Marker for Cytotoxicity?

scientific article

CD70 and PD-L1 in anaplastic thyroid cancer - promising targets for immunotherapy

scientific article published on 6 April 2017

CD70: An emerging target in cancer immunotherapy

scientific article published on 23 July 2015

Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.

scientific article published in January 2004

Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use.

scientific article

Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia ⬇️

scientific article published on April 26, 2011

Clinical use of dendritic cells for cancer therapy.

scientific article

Clinically Relevant Chemotherapeutics Have the Ability to Induce Immunogenic Cell Death in Non-Small Cell Lung Cancer

scientific article published on 16 June 2020

Cold Atmospheric Plasma Treatment for Pancreatic Cancer-The Importance of Pancreatic Stellate Cells

scientific article published on 28 September 2020

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

scientific article published on 19 October 2019

Combining top-ranked immunotherapeutics in lung cancer

scientific article published on 05 April 2018

Creating a robust framework for the analysis of cryopreserved samples in quantitative immunological experiments

scientific article published on 19 March 2013

Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer

scientific article published on 19 September 2019

Dendritic Cells and Programmed Death-1 Blockade: A Joint Venture to Combat Cancer.

scientific article published in March 2018

Dendritic Cells as Pharmacological Tools for Cancer Immunotherapy.

scientific article published on October 2015

Dendritic Cells as Vaccines: Key Regulators of Tolerance and Immunity

scientific article published on 31 May 2016

Dendritic cell vaccine therapy for acute myeloid leukemia: questions and answers

scientific article published on 01 May 2011

Dendritic cell-based cancer gene therapy.

scientific article published on October 2009

Dendritic cells in the pathogenesis and treatment of human diseases: a Janus Bifrons?

scientific article published on October 2011

Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells.

scientific article published on 13 January 2017

Desmoid tumors display a strong immune infiltration at the tumor margins and no PD-L1-driven immune suppression

scientific article published on 11 September 2019

Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing

scientific article published on 07 November 2018

Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions.

scientific article published on 12 April 2015

Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines.

scientific article published on 20 June 2016

Exploring the impact of exposure to primary varicella in children on varicella-zoster virus immunity of parents

scientific article published in April 2011

Generation and Cryopreservation of Clinical Grade Wilms' Tumor 1 mRNA-Loaded Dendritic Cell Vaccines for Cancer Immunotherapy.

scientific article

Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation.

scientific article

HPV vaccine stimulates cytotoxic activity of killer dendritic cells and natural killer cells against HPV-positive tumour cells

scientific article

Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity.

scientific article published on 02 September 2016

Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities.

scientific article published on 10 September 2012

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.

scientific article published on 21 April 2018

IL-15 receptor alpha as the magic wand to boost the success of IL-15 antitumor therapies: The upswing of IL-15 transpresentation.

scientific article

Identification of a Wilms' tumor 1-derived immunogenic CD4(+) T-cell epitope that is recognized in the context of common Caucasian HLA-DR haplotypes.

scientific article published on 29 August 2012

Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia

scientific article published on 17 December 2017

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect

scientific article

Immunotherapy of acute myeloid leukemia: current approaches.

scientific article published on 16 March 2009

Immunotherapy: is a minor god yet in the pantheon of treatments for lung cancer?

scientific article

Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections

scientific article published on 07 August 2017

Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity.

scientific article published in December 2017

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

scientific article

Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment

scientific article published on 01 September 2019

Influence of frequent infectious exposures on general and varicella-zoster virus-specific immune responses in pediatricians

scientific article published on 15 January 2014

Interferon-α in acute myeloid leukemia: an old drug revisited ⬇️

scientific article published on January 28, 2011

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

scientific article published on 7 May 2015

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

scientific article published on 29 September 2016

Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion.

scientific article published on 10 April 2018

Interleukin-15-induced CD56(+) myeloid dendritic cells combine potent tumor antigen presentation with direct tumoricidal potential

scientific article

Interleukin-15: new kid on the block for antitumor combination therapy.

scientific article

Loading of acute myeloid leukemia cells with poly(I:C) by electroporation.

scientific article published on January 2014

Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

scientific article published on 02 April 2020

Medical costs of treatment and survival of patients with acute myeloid leukemia in Belgium

scientific article published on 16 April 2016

Memory CD4 T cell receptor repertoire data mining as a tool for identifying cytomegalovirus serostatus

scientific article published on 15 June 2018

Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments

scientific article published on 02 December 2019

Monocyte-Derived Dendritic Cells with Silenced PD-1 Ligands and Transpresenting Interleukin-15 Stimulate Strong Tumor-Reactive T-cell Expansion

scientific article published on 21 June 2017

Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox

scientific article

NK cells: key to success of DC-based cancer vaccines?

scientific article published on 20 August 2012

Natural killer cell immune escape in acute myeloid leukemia.

scientific article published on 26 March 2012

Natural killer cells and their therapeutic role in pancreatic cancer: A systematic review

scientific article published on 13 April 2018

New targets for therapy: antigen identification in adults with B-cell acute lymphoblastic leukaemia

scientific article published on 22 January 2020

Non-Thermal Plasma as a Unique Delivery System of Short-Lived Reactive Oxygen and Nitrogen Species for Immunogenic Cell Death in Melanoma Cells

scientific article published on 28 January 2019

Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects

scientific article published on 27 November 2020

Poly(I:C) as cancer vaccine adjuvant: knocking on the door of medical breakthroughs.

scientific article published on 02 October 2014

Poly(I:C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC

scientific article

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

scientific article published on 12 December 2017

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.

scientific article

Prognostic and predictive aspects of the tumor immune microenvironment and immune checkpoints in malignant pleural mesothelioma

scientific article published on 28 November 2016

Proinflammatory response of human leukemic cells to dsRNA transfection linked to activation of dendritic cells

scientific article published on 24 May 2007

Quantification of IFN-gamma produced by human purified NK cells following tumor cell stimulation: comparison of three IFN-gamma assays.

scientific article

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review. ⬇️

scientific article published on 2 May 2019

RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment

scientific article published on 03 November 2018

RNA-based gene transfer for adult stem cells and T cells.

scientific article

Reduction of Human Glioblastoma Spheroids Using Cold Atmospheric Plasma: The Combined Effect of Short- and Long-Lived Reactive Species

scientific article published on 23 October 2018

Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready 'N Able to Improve Clinical Outcome?

scientific article published on 27 January 2020

Sampling site matters when counting lymphocyte subpopulations

scientific article

Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method

scientific article published on 22 October 2019

Targeting immune checkpoints: New opportunity for mesothelioma treatment?

scientific article published on 28 September 2015

The potential and controversy of targeting STAT family members in cancer

scientific article published on 09 October 2019

The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy

scientific article published on 16 May 2018

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

scientific article published on 21 September 2016

Transcriptome profiling in blood before and after hepatitis B vaccination shows significant differences in gene expression between responders and non-responders

article

Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity.

scientific article published on 9 December 2015

Tumoricidal activity of human dendritic cells.

scientific article

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

scientific article

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

scientific article published on 19 March 2018

Vaccine and immune cell therapy in non-small cell lung cancer.

scientific article published in May 2018

Viral infections following allogeneic stem cell transplantation: how to cure the cure?

scientific article published on 01 June 2010

mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients.

scientific article published on February 2012

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