Search filters

List of works by Christopher J Jackson

Aberrant levels of natural IgM antibodies in osteoarthritis and rheumatoid arthritis patients in comparison to healthy controls.

scientific article published on 29 December 2015

Activated Protein C Enhances Human Keratinocyte Barrier Integrity via Sequential Activation of Epidermal Growth Factor Receptor and Tie2 ⬇️

scientific article published on December 20, 2010

Activated Protein C in Cutaneous Wound Healing: From Bench to Bedside

scientific article published on 19 February 2019

Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism

scientific article published on 15 September 2014

Activated protein C and its potential applications in prevention of islet β-cell damage and diabetes.

scientific article published on January 2014

Activated protein C binds directly to Tie2: possible beneficial effects on endothelial barrier function.

scientific article published on 22 December 2016

Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates

scientific article published on 15 February 2013

Activated protein C directly activates human endothelial gelatinase A

scientific article published on 01 March 2000

Activated protein C improves left ventricular remodelling after ischemia-reperfusion injury in rats

scientific article published on 17 June 2012

Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice

scientific article

Activated protein C inhibits proliferation and tumor necrosis factor α-stimulated activation of p38, c-Jun NH2-terminal kinase (JNK) and Akt in rheumatoid synovial fibroblasts

scientific article

Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing.

scientific article published in May 2005

Activated protein C stimulates proliferation, migration and wound closure, inhibits apoptosis and upregulates MMP-2 activity in cultured human keratinocytes.

scientific article

Activated protein C to heal pressure ulcers.

scientific article

Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function.

scientific article published on 26 October 2009

Active and tissue inhibitor of matrix metalloproteinase-free gelatinase B accumulates within human microvascular endothelial vesicles

scientific article published on 01 February 1998

Anti-IgD antibody attenuates collagen-induced arthritis by selectively depleting mature B-cells and promoting immune tolerance

scientific article

Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects

scientific article published on 15 September 2020

Autocrine actions of matrix metalloproteinase (MMP)-2 counter the effects of MMP-9 to promote survival and prevent terminal differentiation of cultured human keratinocytes

scientific article published on 22 May 2008

Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cellsviadeath receptor 5 upregulation ⬇️

scientific article published on March 31, 2011

Characterisation of the macroporosity of polycaprolactone-based biocomposites and release kinetics for drug delivery.

scientific article published on 30 July 2007

Combination of activated protein C and topical negative pressure rapidly regenerates granulation tissue over exposed bone to heal recalcitrant orthopedic wounds

scientific article published on 01 August 2011

Constitutive secretion of MMP9 by early-passage cultured human endothelial cells.

scientific article published on December 2003

Corrigendum to "Lupeol, a Dietary Triterpene, Enhances Wound Healing in Streptozotocin-Induced Hyperglycemic Rats with Modulatory Effects on Inflammation, Oxidative Stress, and Angiogenesis"

scientific article published on 27 May 2020

Delivery systems of current biologicals for the treatment of chronic cutaneous wounds and severe burns

scientific article published on 19 March 2018

Differential effects of photofrin, 5-aminolevulinic acid and calphostin C on glioma cells.

scientific article published on 10 July 2006

Differential regulation of matrix metalloproteinase 2 and matrix metalloproteinase 9 by activated protein C: relevance to inflammation in rheumatoid arthritis

scientific article published on 01 September 2007

Effect of activated protein C in second intention healing of equine distal limb wounds: a preliminary study

scientific article published in October 2015

Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2

scientific article

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.

scientific article published on 29 June 2014

Endogenous protein C is essential for the functional integrity of human endothelial cells

scientific article published on 03 February 2010

Endothelial protein C receptor and protease-activated receptor-1 mediate induction of a wound-healing phenotype in human keratinocytes by activated protein C

scientific article published on 01 December 2005

Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2.

scientific article published on 05 February 2014

Human cortical fibroblast responses to high glucose and hypoxia

scientific article published on 01 January 2004

Human microvascular endothelial cells differ from macrovascular endothelial cells in their expression of matrix metalloproteinases ⬇️

scientific article published on October 1, 1997

Hyaluronan inhibits matrix metalloproteinase-13 in human arthritic chondrocytes via CD44 and P38.

scientific article

In vitro migration of cytotrophoblasts through a decidual endothelial cell monolayer: the role of matrix metalloproteinases.

scientific article published in April 2003

Inflammation in Chronic Wounds

scientific article

Interaction of cocultured decidual endothelial cells and cytotrophoblasts in preeclampsia.

scientific article published on 17 March 2004

Intercellular adhesion molecule-1 (ICAM-1) expression is necessary for monocyte adhesion to the placental bed endothelium and is increased in type 1 diabetic human pregnancy.

scientific article

Isolation and propagation of endothelial cells derived from rheumatoid synovial microvasculature.

scientific article

Isolation and purification of microvascular endothelium from human decidual tissue in the late phase of pregancy ⬇️

scientific article published on July 1, 1991

Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes.

scientific article published in November 2005

Low circulating protein C levels are associated with lower leg ulcers in patients with diabetes

scientific article published on 2 January 2013

Lupeol, a Dietary Triterpene, Enhances Wound Healing in Streptozotocin-Induced Hyperglycemic Rats with Modulatory Effects on Inflammation, Oxidative Stress, and Angiogenesis

scientific article published on 09 May 2019

Lupeol, a Pentacyclic Triterpene, Promotes Migration, Wound Closure, and Contractile Effect In Vitro: Possible Involvement of PI3K/Akt and p38/ERK/MAPK Pathways

scientific article published on 30 October 2018

Microenvironment and macroenvironment in hypertensive hearts: boundaries and silos--can we pick and treat diastolic heart failure?

scientific article published on 19 April 2010

Monocyte adhesion to decidual endothelial cells is increased in pregnancies complicated by type 1 diabetes but not by gestational diabetes.

scientific article

Myocardial extracellular matrix remodeling in ischemic heart failure.

scientific article published on January 2007

New therapeutic applications for the anticoagulant, activated protein C

scientific article published in August 2008

Novel Functions of the Anticoagulant Activated Protein C in Maintaining Skin Barrier Integrity to Impact on Skin Disease.

scientific article published on 07 July 2015

Plasma protein C levels are directly associated with better outcomes in patients with severe burns

scientific article published on 18 June 2019

Preeclamptic decidual microvascular endothelial cells express lower levels of matrix metalloproteinase-1 than normals.

scientific article

Prognostic significance of growth factors and the urokinase-type plasminogen activator system in pancreatic ductal adenocarcinoma

scientific article

Protease Activated Receptor-2 Mediates Activated Protein C–Induced Cutaneous Wound Healing via Inhibition of p38 ⬇️

scientific article published on September 9, 2011

Protease-activated receptor 2, rather than protease-activated receptor 1, contributes to the aggressive properties of synovial fibroblasts in rheumatoid arthritis

scientific article published on 01 January 2012

Protein C is an autocrine growth factor for human skin keratinocytes

scientific article published on 09 February 2007

Regional cardiac dysfunction is associated with specific alterations in inflammatory cytokines and matrix metalloproteinases after acute myocardial infarction in sheep

scientific article published on 04 July 2006

Review of Toxic Epidermal Necrolysis

scientific article

SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes.

scientific article published on 19 December 2012

Sphingosine-1-phosphate protects against bisphosphonate‑induced HUVEC cell death via regulation of c-Jun‑N‑terminal kinase signaling.

scientific article published on 04 February 2013

Sulfated polysaccharides are required for collagen-induced vascular tube formation.

scientific article published on December 1994

Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling.

scientific article

The Endothelial Protein C Receptor Is a Potential Stem Cell Marker for Epidermal Keratinocytes.

scientific article published on 7 May 2017

The chondroprotective drugs, Arteparon and sodium pentosan polysulphate, increase collagenase activity and inhibit stromelysin activity in vitro

scientific article published on 01 October 1992

The differential expression of protease activated receptors contributes to functional differences between dark and fair keratinocytes.

scientific article published on 5 December 2016

Three-dimensional collagen matrices induce delayed but sustained activation of gelatinase A in human endothelial cells via MT1-MMP

scientific article published on 01 June 2000

Toxic epidermal necrolysis: review of pathogenesis and management.

scientific article published on 09 December 2011

Treatment of chronic leg ulcers with topical activated protein C.

scientific article published in November 2008

Type I collagen fibrils promote rapid vascular tube formation upon contact with the apical side of cultured endothelium.

scientific article published in January 1991

Use of dermal injection of activated protein C for treatment of large chronic wounds secondary to pyoderma gangrenosum

scientific article published on 22 August 2014

VLA-2 mediates the interaction of collagen with endothelium during in vitro vascular tube formation

scientific article published on 01 September 1994

Paulina is supported by:

About Paulina

Help