List of works by Gennaro De Libero

'Bohemian Rhapsody' of MR1T cells

scientific article published on 01 February 2020

4,5,6-Trisubstituted piperidinones as conformationally restricted ceramide analogues: synthesis and evaluation as inhibitors of sphingosine and ceramide kinases and as NKT cell-stimulatory antigens

scientific article published in October 2009

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias

scientific article

A semisynthetic carbohydrate-lipid vaccine that protects against S. pneumoniae in mice

scientific article published on 5 October 2014

Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T Cells upon Controlled Infection with Plasmodium falciparum in Tanzanian Volunteers

scientific article published on 04 December 2019

Assistance of microbial glycolipid antigen processing by CD1e

scientific article

Bacterial infections promote T cell recognition of self-glycolipids

scientific article published in June 2005

Broad-Spectrum Antimicrobial Star Polycarbonates Functionalized with Mannose for Targeting Bacteria Residing inside Immune Cells

scientific article published on 29 March 2016

Butyrophilin 3A (BTN3A, CD277)-specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation

scientific article published on 6 April 2017

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

scientific article

CD1a and CD1b surface expression is independent from de novo synthesized glycosphingolipids

scientific article published on January 2003

CD1a and MHC class I follow a similar endocytic recycling pathway

scientific article

CD1a-binding glycosphingolipids stimulating human autoreactive T-cells: synthesis of a family of sulfatides differing in the acyl chain moiety

article published in 2002

Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations

scientific article

Contact sensitizers trigger human CD1-autoreactive T-cell responses

scientific article published on 25 April 2017

Correction: Functionally diverse human T cells recognize non-microbial antigens presented by MR1.

scientific article published on 20 June 2017

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

scientific article

Cutting edge: a naturally occurring mutation in CD1e impairs lipid antigen presentation

scientific article

Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis

scientific article

Differentiation of monocytes into CD1a- dendritic cells correlates with disease progression in HIV-infected patients

scientific article published in December 2007

Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells

scientific article published in August 2008

Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens

scientific article

Emerging technologies for monitoring drug-resistant tuberculosis at the point-of-care

scientific article

Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b

scientific article

Erratum: Corrigendum: Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

scientific article published in Nature Communications

Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response.

scientific article

Fine tuning by human CD1e of lipid-specific immune responses

scientific article

From Immunologically Archaic to Neoteric Glycovaccines

scientific article

Functional CD1a is stabilized by exogenous lipids

scientific article

Functionally diverse human T cells recognize non-microbial antigens presented by MR1.

scientific article published on 18 May 2017

Hemopoietic cell kinase (Hck) and p21-activated kinase 2 (PAK2) are involved in the down-regulation of CD1a lipid antigen presentation by HIV-1 Nef in dendritic cells

scientific article

High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells

scientific article

How T cells get grip on lipid antigens

scientific article published on 11 December 2007

How T lymphocytes recognize lipid antigens

scientific article published on 28 August 2006

How pattern recognition receptor triggering influences T cell responses: a new look into the system.

scientific article published on 29 May 2007

How the immune system detects lipid antigens

scientific article published on 24 October 2009

Human CD1-restricted T cell recognition of lipids from pollens

scientific article

Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells

scientific article

IL-8-mediated angiogenic responses of endothelial cells to lipid antigen activation of iNKT cells depend on EGFR transactivation

scientific article

In situ correlation of cytokine secretion and apoptosis in Helicobacter pylori-associated gastritis

scientific article published on August 2002

Interferon lambda 4 can directly activate human CD19+ B cells and CD8+ T cells

scientific article published on 06 November 2020

Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis

scientific article published on 27 October 2010

Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias

scientific article

Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens

scientific article published in September 2016

MR1-restricted Valpha19i T cells: a second population recognizing lipid antigens?

scientific article published on July 2007

Mechanisms of lipid-antigen generation and presentation to T cells

scientific article published on 5 September 2006

Metformin as adjunct antituberculosis therapy

scientific article published on November 2014

Modification of the ceramide moiety of isoglobotrihexosylceramide on its agonist activity in stimulation of invariant natural killer T cells

scientific article

Mycobacteria exploit p38 signaling to affect CD1 expression and lipid antigen presentation by human dendritic cells

scientific article published on 31 August 2009

Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells

scientific article published in January 2009

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

scientific article published on 2 November 2017

Novel insights into lipid antigen presentation

scientific article published on 16 February 2012

Phosphoantigen Presentation to TCR γδ Cells, a Conundrum Getting Less Gray Zones

scientific article

Point-of-care assays for tuberculosis: role of nanotechnology/microfluidics

scientific article

Presentation of lipid antigens to T cells

scientific article published on 15 January 2008

Recognition of lipid antigens by T cells

scientific article

Regulation of CD1a surface expression and antigen presentation by invariant chain and lipid rafts.

scientific article published in January 2008

Self glycosphingolipids: new antigens recognized by autoreactive T lymphocytes.

scientific article

Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity

scientific article published on 31 October 2013

Stroke research priorities for the next decade--A representative view of the European scientific community

scientific article published in January 2006

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

scientific article

Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3).

scientific article published on 2 February 2006

Synthesis and evaluation of human T cell stimulating activity of an alpha-sulfatide analogue

scientific article published on 23 May 2007

Synthesis and evaluation of sphingolipid analogues: modification of the hydroxy group at C(1) of 7-oxasphingosine, and of the hydroxy group at C(1) and the amide group of 7-oxaceramides.

scientific article published in May 2009

Synthesis of 7-aza- and 7-thiasphingosines, and evaluation of their interaction with sphingosine kinases and with T-cells.

scientific article published in May 2009

Synthesis of diacylated trehalose sulfates: candidates for a tuberculosis vaccine

scientific article

T cells specific for lipid antigens

scientific article published on September 2012

Targeting leukemia by CD1c-restricted T cells specific for a novel lipid antigen

scientific article

The HOX gene network in hepatocellular carcinoma.

scientific article published on 30 May 2011

The Immunology of CD1- and MR1-Restricted T Cells

scientific article published on 25 February 2016

The T-Cell Response to Lipid Antigens of Mycobacterium tuberculosis

scientific article

The cellular and biochemical rules of lipid antigen presentation

scientific article published on October 2009

The role of innate immunity in autoimmunity.

scientific article published on December 2004

Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver

scientific article

Unique T-Cell Populations Define Immune-Inflamed Hepatocellular Carcinoma

scientific article published on 22 August 2019

rCASC: reproducible classification analysis of single-cell sequencing data

scientific article published on 01 September 2019

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