List of works - Tomoko Kawai

A non-toxic heat shock protein 70 inducer, geranyl-geranyl-acetone, restores the heat shock response in gastric mucosa of protein-malnourished rats

scientific article published on 01 August 2000

A novel CUL4B splice site variant in a young male exhibiting less pronounced features

scientific article published on 04 September 2019

A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA

scientific article

AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

scientific article published on September 2004

Adverse parenting is associated with blunted salivary cortisol awakening response and altered expression of glucocorticoid receptor β and β2-adrenergic receptor mRNAs in leukocytes in Japanese medical students.

scientific article published on 12 March 2017

Associations between chronotype and salivary endocrinological stress markers.

scientific article published on 16 May 2012

Autism-associated gene expression in peripheral leucocytes commonly observed between subjects with autism and healthy women having autistic children

scientific article

Brief naturalistic stress induces an alternative splice variant of SMG-1 lacking exon 63 in peripheral leukocytes.

scientific article published on 17 August 2010

Circulating vascular endothelial growth factor is independently and negatively associated with trait anxiety and depressive mood in healthy Japanese university students ⬇️

scientific article published on May 3, 2011

Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes

scientific article published on 15 June 2019

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

scientific article published on 30 September 2020

Correction to: Gene expression and DNA methylation changes in BeWo cells dependent on tumor necrosis factor-α and insulin-like growth factor-I

scientific article published on 01 January 2020

DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation

scientific article

DNA methylation changes involved in the tumor increase in F2 males born to gestationally arsenite-exposed F1 male mice

scientific article published on 25 July 2019

DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes

scientific article published on 15 November 2019

Effects of chronic academic stress on mental state and expression of glucocorticoid receptor α and β isoforms in healthy Japanese medical students.

scientific article published on 27 March 2011

Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR

scientific article

Epitranscriptomic profiling in human placenta: N6-methyladenosine modification at the 5'-untranslated region is related to fetal growth and preeclampsia

scientific article published on 25 November 2019

Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach.

scientific article

Gene expression and DNA methylation changes in BeWo cells dependent on tumor necrosis factor-α and insulin-like growth factor-I

scientific article published on 13 November 2019

Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity

scientific article published on 12 February 2016

Gene expression signature in peripheral blood cells from medical students exposed to chronic psychological stress.

scientific article published on 31 July 2007

Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase

scientific article published on 01 January 2000

Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells.

scientific article

High-throughput screening of brief naturalistic stress-responsive cytokines in university students taking examinations.

scientific article published on 17 May 2010

Human cytomegalovirus downregulates SLITRK6 expression through IE2.

scientific article published on 16 August 2016

Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand

scientific article published on 15 February 2018

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

scientific article published on 01 March 2011

Increased epigenetic alterations at the promoters of transcriptional regulators following inadequate maternal gestational weight gain.

scientific article

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

scientific article published on 10 September 2019

Integrated molecular characterization of the lethal pediatric cancer pancreatoblastoma

scientific article

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

scientific article published on 07 July 2020

Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon

scientific article published on 28 August 2009

Interleukin-18 is a crucial determinant of vulnerability of the mouse rectum to psychosocial stress

scientific article published on 13 January 2009

Lists of HumanMethylation450 BeadChip probes with nucleotide-variant information obtained from the Phase 3 data of the 1000 Genomes Project

scientific article

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.

scientific article

Novel SIN3A mutation identified in a Japanese patient with Witteveen-Kolk syndrome

scientific article published on 26 September 2018

Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality.

scientific article

Physical exercise-associated gene expression signatures in peripheral blood

scientific article published on 01 September 2007

Placental Development and Nutritional Environment

scientific article published on 01 January 2018

Posttranscriptional derepression of GADD45alpha by genotoxic stress.

scientific article

Receptor activator of nuclear factor-kappaB ligand-induced mouse osteoclast differentiation is associated with switching between NADPH oxidase homologues.

scientific article published on 3 May 2009

Reproductive/Developmental Abnormalities Induced by Epigenetic Aberrations and Possible Environmental Causes.

scientific article

The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes.

scientific article published on 22 March 2018

Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.

scientific article published on 23 September 2008

List of works by Tomoko Kawai

A non-toxic heat shock protein 70 inducer, geranyl-geranyl-acetone, restores the heat shock response in gastric mucosa of protein-malnourished rats

A novel CUL4B splice site variant in a young male exhibiting less pronounced features

A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA

AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

Adverse parenting is associated with blunted salivary cortisol awakening response and altered expression of glucocorticoid receptor β and β2-adrenergic receptor mRNAs in leukocytes in Japanese medical students.

Associations between chronotype and salivary endocrinological stress markers.

Autism-associated gene expression in peripheral leucocytes commonly observed between subjects with autism and healthy women having autistic children

Brief naturalistic stress induces an alternative splice variant of SMG-1 lacking exon 63 in peripheral leukocytes.

Circulating vascular endothelial growth factor is independently and negatively associated with trait anxiety and depressive mood in healthy Japanese university students ⬇️

Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

Correction to: Gene expression and DNA methylation changes in BeWo cells dependent on tumor necrosis factor-α and insulin-like growth factor-I

DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation

DNA methylation changes involved in the tumor increase in F2 males born to gestationally arsenite-exposed F1 male mice

DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes

Effects of chronic academic stress on mental state and expression of glucocorticoid receptor α and β isoforms in healthy Japanese medical students.

Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR

Epitranscriptomic profiling in human placenta: N6-methyladenosine modification at the 5'-untranslated region is related to fetal growth and preeclampsia

Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach.

Gene expression and DNA methylation changes in BeWo cells dependent on tumor necrosis factor-α and insulin-like growth factor-I

Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity

Gene expression signature in peripheral blood cells from medical students exposed to chronic psychological stress.

Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase

Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells.

High-throughput screening of brief naturalistic stress-responsive cytokines in university students taking examinations.

Human cytomegalovirus downregulates SLITRK6 expression through IE2.

Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Increased epigenetic alterations at the promoters of transcriptional regulators following inadequate maternal gestational weight gain.

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Integrated molecular characterization of the lethal pediatric cancer pancreatoblastoma

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon

Interleukin-18 is a crucial determinant of vulnerability of the mouse rectum to psychosocial stress

Lists of HumanMethylation450 BeadChip probes with nucleotide-variant information obtained from the Phase 3 data of the 1000 Genomes Project

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.

Novel SIN3A mutation identified in a Japanese patient with Witteveen-Kolk syndrome

Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality.

Physical exercise-associated gene expression signatures in peripheral blood

Placental Development and Nutritional Environment

Posttranscriptional derepression of GADD45alpha by genotoxic stress.

Receptor activator of nuclear factor-kappaB ligand-induced mouse osteoclast differentiation is associated with switching between NADPH oxidase homologues.

Reproductive/Developmental Abnormalities Induced by Epigenetic Aberrations and Possible Environmental Causes.

The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes.

Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.