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List of works by Birgit Koch

A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation

scientific article

A clinically relevant pharmacokinetic interaction between cyclosporine and imatinib

scientific article published on 11 March 2016

A fast and sensitive LC-MS/MS method for the quantification of fosfomycin in human urine and plasma using one sample preparation method and HILIC chromatography

scientific article

A new challenge: suicide attempt using nicotine fillings for electronic cigarettes.

scientific article published in December 2014

An observational study on disturbed peripheral circadian rhythms in hemodialysis patients

scientific article

Antipsychotics in Dutch Youth: Prevalence, Dosages, and Duration of Use from 2005 to 2015

scientific article published on 13 March 2018

Big data analyses for continuous evaluation of pharmacotherapy: A proof of principle with doxapram in preterm infants

scientific article published on 18 September 2017

Bioequivalence study of an extemporaneously prepared oral solution of amlodipine suitable for use in pediatric patients compared to commercial tablets

scientific article published on 01 January 2016

CYP3A5 and ABCB1 polymorphisms in living donors do not impact clinical outcome after kidney transplantation

scientific article published on 11 July 2018

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

scientific article published on 7 June 2015

Clinical applications of population pharmacokinetic models of antibiotics: Challenges and perspectives

scientific article published on 06 July 2018

Combination Therapy of Etanercept and Fumarates versus Etanercept Monotherapy in Psoriasis: A Randomized Exploratory Study

scientific article published on September 2016

Combining biologics with methotrexate in psoriasis: a systematic review

scientific article published on 29 April 2015

Comparison of Three Assays to Quantify Infliximab, Adalimumab, and Etanercept Serum Concentrations

scientific article published on 01 August 2016

Converting cyclosporine A from intravenous to oral administration in hematopoietic stem cell transplant recipients and the role of azole antifungals.

scientific article published on 2 March 2018

Cytochrome P450 2D6 poor metabolism, curvilinearity, and response: an intriguing observation requiring integration of psychopharmacology into pharmacogenetics

scientific article published in December 2013

Design and stability study of an oral solution of amlodipine besylate for pediatric patients

scientific article published on 20 May 2016

Development and Validation of an HPLC-UV Assay to Quantify Plasma Levels of Sulfametrol: A Preferential Antibiotic in Children.

scientific article published on 28 March 2015

Development and validation of a paediatric oral formulation of clonidine hydrochloride

scientific article published on 09 May 2012

Different melatonin rhythms and sleep-wake rhythms in patients on peritoneal dialysis, daytime hemodialysis and nocturnal hemodialysis.

scientific article published on 10 July 2009

Doubt about the feasibility of preemptive genotyping.

scientific article published on 12 December 2012

Doxazosin treatment of phaeochromocytoma during pregnancy: placental transfer and disposition in breast milk.

scientific article published on 19 May 2016

Dried Blood Spots Combined With Ultra-High-Performance Liquid Chromatography-Mass Spectrometry for the Quantification of the Antipsychotics Risperidone, Aripiprazole, Pipamperone, and Their Major Metabolites

scientific article published in August 2017

Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate--a validated assay for the clinic.

scientific article

Formulating a poorly water soluble drug into an oral solution suitable for paediatric patients; lorazepam as a model drug

scientific article published on 23 January 2017

Gain-of-function single nucleotide variants of the CYP2C19 gene (CYP2C19*17) can identify subtherapeutic voriconazole concentrations in critically ill patients: a case series

scientific article published on 04 August 2015

High interindividual variability in urinary fosfomycin concentrations in healthy female volunteers

scientific article

High-throughput quantification of 8 antihypertensive drugs and active metabolites in human plasma using UPLC-MS/MS.

scientific article published on 19 June 2017

Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect?

scientific article

Identification and quantification of the antipsychotics risperidone, aripiprazole, pipamperone and their major metabolites in plasma using ultra-high performance liquid chromatography-mass spectrometry.

scientific article published on 7 September 2015

Impairment of endogenous melatonin rhythm is related to the degree of chronic kidney disease (CREAM study).

scientific article published on 19 September 2009

In Vitro Adsorption of Analgosedative Drugs in New Extracorporeal Membrane Oxygenation Circuits

scientific article published on 6 February 2018

Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children

scientific article

Insufficient serum caspofungin levels in a paediatric patient on ECMO.

scientific article published on 26 December 2012

Intoxication of a Young Girl Reveals the Pitfalls of GHB Rapid Screening.

scientific article published on 28 August 2015

Intrapatient Variability in the Pharmacokinetics of Etanercept Maintenance Treatment

scientific article published on 01 August 2017

Long‐term effects of melatonin on quality of life and sleep in haemodialysis patients (Melody study): a randomized controlled trial ⬇️

scientific article published on November 1, 2013

Monitoring antigen-specific biologics: current knowledge and future prospects.

scientific article published on October 2013

Monitoring the Tacrolimus Concentration in peripheral bLood mononuclear cells of Kidney Transplant Recipients

scientific article published on 06 October 2020

Non-linear absorption pharmacokinetics of amoxicillin: consequences for dosing regimens and clinical breakpoints.

scientific article published on 20 June 2016

Pharmacokinetic considerations and recommendations in palliative care, with focus on morphine, midazolam and haloperidol.

scientific article published on 15 April 2016

Pharmacokinetics and target attainment of mycophenolate in pediatric renal transplant patients.

scientific article published on 29 February 2016

Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients.

scientific article published on 29 December 2015

Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients.

scientific article published on 27 September 2017

Population pharmacokinetics of haloperidol in terminally ill adult patients.

scientific article

Prolongation of Biologic Dosing Intervals in Patients With Stable Psoriasis: A Feasibility Study

scientific article

Prolonged influenza virus shedding and emergence of antiviral resistance in immunocompromised patients and ferrets

scientific article

Quantification of Acetaminophen and Its Metabolites in Plasma Using UPLC-MS: Doors Open to Therapeutic Drug Monitoring in Special Patient Populations

scientific article

Response: Co-administration of cyclosporine A and imatinib among patients with Philadelphia chromosome-positive leukemias in the post-transplant setting.

scientific article

Risperidone plasma concentrations are associated with side-effects and effectiveness in children and adolescents with autism spectrum disorder

scientific article published on 09 July 2020

Simultaneous determination of nine β-lactam antibiotics in human plasma by an ultrafast hydrophilic-interaction chromatography-tandem mass spectrometry

scientific article published on 8 June 2017

Stability of colistimethate sodium in a disposable elastomeric infusion device

scientific article published on 8 April 2015

Stability of sildenafil (Revatio®) dilutions in dextrose 5%

scientific article published on 27 September 2011

The effects of kidney transplantation on sleep, melatonin, circadian rhythm and quality of life in kidney transplant recipients and living donors.

scientific article published on 18 December 2014

The effects of melatonin on sleep-wake rhythm of daytime haemodialysis patients: a randomized, placebo-controlled, cross-over study (EMSCAP study)

scientific article

The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison

scientific article published on 15 August 2015

The role of melatonin treatment in chronic kidney disease.

scientific article published on June 2012

Therapeutic Drug Monitoring in Neonates: what makes them unique?

scientific article published on 26 September 2017

Using fluorescence polarization immunoassay for determination of erythrocyte methotrexate polyglutamates, a quick and easy test?

scientific article published on 01 December 2014

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