List of works - Kendra K Bence

Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance

scientific article

Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity

scientific article published on 12 June 2020

Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis

scientific article

Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance.

scientific article published on March 2016

Central regulation of metabolism by protein tyrosine phosphatases

scientific article published on January 2012

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

scientific article published on 9 November 2017

Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure ⬇️

scientific article published on March 15, 2011

Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.

scientific article

Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension.

scientific article published on 30 October 2015

Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit ⬇️

scientific article published on September 18, 1997

Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance

scientific article published on 30 December 2008

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance

scientific article published on 13 October 2011

Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals ⬇️

scientific article published on June 12, 2012

Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation

scientific article

Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.

scientific article published on 17 August 2011

Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.

scientific article

Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling

scientific article published on 01 July 1997

Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.

scientific article published on 19 January 2014

Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice.

scientific article published on 6 July 2013

Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor

scientific article published on 01 May 1997

Leptin and insulin act on POMC neurons to promote the browning of white fat.

scientific article published on January 2015

Melanocortin control of energy balance: evidence from rodent models

scientific article

Neuronal PTP1B regulates body weight, adiposity and leptin action.

scientific article published on 16 July 2006

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

scientific article published on 15 June 2009

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

scientific article

Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies

scientific article

Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.

scientific article

Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling

scientific article

Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms

scientific article published on 2 March 2016

Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B.

scientific article published on 4 December 2012

The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency

scientific article

List of works by Kendra K Bence

Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance

Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity

Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis

Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance.

Central regulation of metabolism by protein tyrosine phosphatases

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure ⬇️

Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.

Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension.

Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit ⬇️

Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance

Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals ⬇️

Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation

Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.

Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency.

Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling

Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.

Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice.

Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor

Leptin and insulin act on POMC neurons to promote the browning of white fat.

Melanocortin control of energy balance: evidence from rodent models

Neuronal PTP1B regulates body weight, adiposity and leptin action.

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies

Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.

Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling

Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms

Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B.

The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency