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List of works by Philippe Lefebvre

Author Correction: Transcriptional network analysis implicates altered hepatic immune function in NASH development and resolution

scientific article published on 01 July 2019

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects

scientific article

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

scientific article published on 15 February 2017

CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway

scientific article published on 09 October 2020

Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex

article published in the Proceedings of the National Academy of Sciences of the United States of America

Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity

scientific article

Distinct but complementary contributions of PPAR isotypes to energy homeostasis.

scientific article

Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects

scientific article published on 19 September 2016

Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver

scientific article published on 01 May 2020

Expression patterns of miR-96, miR-182 and miR-183 in the development inner ear.

scientific article published in June 2009

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

scientific article

Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10.

scientific article

Hair cell progenitors: identification and regulatory genes

scientific article published on March 2010

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

scientific article published on 11 April 2019

Identification of factors that maintain mammalian outer hair cells in adult organ of Corti explants

scientific article

Induction of CXCR2 receptor by peroxisome proliferator-activated receptor gamma in human macrophages

scientific article published on 21 February 2008

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin

scientific article

Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency

scientific article

Nur77turing Macrophages in Atherosclerosis

Peroxisome proliferator-activated receptor-γ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages.

scientific article published on 29 December 2011

Proliferative generation of mammalian auditory hair cells in culture

scientific article published in March 2002

Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis

scientific article

Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti

scientific article published on 11 September 2009

Strategies to regenerate hair cells: identification of progenitors and critical genes.

scientific article published on 06 September 2007

The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.

scientific article published on 26 October 2017

The conundrum of the functional relationship between transcription factors and chromatin

scientific article published in 2022

The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions

scientific article published on 11 April 2017

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice

article

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