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List of works by Paolo Plevani

A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1.

scientific article

A role for DNA primase in coupling DNA replication to DNA damage response.

scientific article published on February 1997

Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase.

scientific article published on November 1999

Bimodal regulation of p21(waf1) protein as function of DNA damage levels

scientific article

Budding Yeast DNA Damage Checkpoint: A Signal Transduction-Mediated Surveillance System

Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.

scientific article published on 9 May 2008

Checkpoint mechanisms at the intersection between DNA damage and repair

scientific article published on 03 June 2009

Control of DNA synthesis genes in budding yeast: involvement of the transcriptional modulator MOT1 in the expression of the DNA polymerase alpha gene

scientific article published on 01 January 1992

Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1.

scientific article published on 2 April 2003

DNA damage checkpoint in budding yeast.

scientific article

DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.

scientific article

DNA decay and limited Rad53 activation after liquid holding of UV-treated nucleotide excision repair deficient S. cerevisiae cells

scientific article published on 01 December 2004

DNA nucleotide excision repair-dependent signaling to checkpoint activation

scientific article

DNA synthesis catalyzed in vitro by yeast extracts using A 2 μm DNA containing plasmid as template for enzymatic DNA synthesis

scientific article published in October 1982

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

scientific article

Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway

scientific article

Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha.

scientific article

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

scientific article

Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis

scientific article published on 01 March 1990

Genetic mapping of the Saccharomyces cerevisiae DNA polymerase I gene and characterization of a pol1 temperature-sensitive mutant altered in DNA primase-polymerase complex stability.

scientific article published in June 1988

Hedgehogs, humans and high-school science. The benefits of involving high-school students in university research.

scientific article

Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation ⬇️

scientific article published on August 16, 2011

In vivo and in vitro effects of rifampicin and streptolydigin on transcription of Kluyveromyces lactis in the presence of nystatin ⬇️

scientific article published on February 1, 1975

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

scientific article

Mind the gap: keeping UV lesions in check.

scientific article published on 23 May 2011

Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.

scientific article

NER and DDR: classical music with new instruments.

scientific article

Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.

scientific article

Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae

scientific article published on 01 May 1990

One-step high-throughput assay for quantitative detection of beta-galactosidase activity in intact gram-negative bacteria, yeast, and mammalian cells

scientific article published on April 2006

Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair.

scientific article published in January 2010

Overproduction and functional analysis of DNA primase subunits from yeast and mouse

scientific article published on 01 April 1992

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint

scientific article

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex

scientific article published on 24 November 2010

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

scientific article

Polypeptide structure of human terminal transferase

scientific article published on 01 October 1982

Positive cis-acting regulatory sequences mediate proper control of POL1 transcription in Saccharomyces cerevisiae.

scientific article

RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

scientific article published on January 2012

Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability

scientific article

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair

scientific article

Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε

scientific article

Sometimes size does matter

scientific article published in July 2003

Stimulation of poly(dT) transcription by Bacillus subtilis RNA polymerase in the presence of adenosine monophosphate

scientific article published on 01 March 1981

Synthesis of RNA and protein in a mutant of Bacillus subtilis temperature sensitive during spore germination

scientific article published on 01 October 1976

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae

scientific article

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

scientific article

The DNA replication checkpoint response stabilizes stalled replication forks

scientific article (publication date: 2 August 2001)

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

scientific article

The yeast DNA polymerase I transcript is regulated in both the mitotic cell cycle and in meiosis and is also induced after DNA damage.

scientific article

To trim or not to trim: progression and control of DSB end resection

scientific article published on 29 May 2013

Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1

Yeast haspin kinase regulates polarity cues necessary for mitotic spindle positioning and is required to tolerate mitotic arrest.

scientific article

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