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List of works by Giampiero Muccioli

A Novel Series of Growth Hormone Secretagogues

Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase γ and phosphodiesterase 3B

scientific journal article

Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl

scientific article published on 26 October 2006

Beyond the metabolic role of ghrelin: a new player in the regulation of reproductive function

scientific article published on 29 October 2011

Biochemical study of prolactin binding sites in Xenopus laevis brain and choroid plexus.

scientific article published in March 1990

Brain-gut communication: cortistatin, somatostatin and ghrelin.

scientific article published on 13 July 2007

Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin.

scientific article

Cardiac effects of hexarelin in hypopituitary adults

scientific article published on 01 September 1999

Changes in prolactin binding sites in the rabbit hypothalamus induced by physiological and pharmacological variations of prolactin serum levels.

scientific article published in December 1981

Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21.

scientific article published on January 2012

Characterization of prolactin receptor in human brain and choroid plexus.

scientific article

Cortistatin-17 and somatostatin-14 display the same effects on growth hormone, prolactin, and insulin secretion in patients with acromegaly or prolactinoma.

scientific article published on 31 January 2006

Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans.

scientific article published on 3 December 2007

Des-acyl ghrelin has specific binding sites and different metabolic effects from ghrelin in cardiomyocytes.

scientific article published on 21 April 2010

Drug-induced membrane modifications differentially affect prolactin and insulin binding in the mouse liver

scientific article published on 01 October 1985

Effect of L-alpha glycerylphosphorylcholine on muscarinic receptors and membrane microviscosity of aged rat brain.

scientific article published in February 1996

Effect of S-adenosyl-L-methionine on brain muscarinic receptors of aged rats

scientific article published on November 2, 1992

Effects of acute hexarelin administration on cardiac performance in patients with coronary artery disease during by-pass surgery.

scientific article published in July 2002

Effects of medroxyprogesterone acetate on serum prolactin levels and liver prolactin binding capacity in the rat

scientific article published on 01 August 1988

Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans

scientific article

Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone.

scientific article

Evidence for a role of the GHS-R1a receptors in ghrelin inhibition of gastric acid secretion in the rat.

scientific article published on February 2006

Expression of cortistatin and MrgX2, a specific cortistatin receptor, in human neuroendocrine tissues and related tumours.

scientific article

Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines

scientific article published on February 2004

Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors

scientific article published on 01 March 2002

Further study on the changes in the concentration of prolactin-binding sites in different organs of Xenopus laevis male and female, kept under dry conditions and then returned to water (their natural habitat)

scientific article published on 01 June 1989

Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor

scientific article published in September 2004

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

scientific article published on 16 December 2002

Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.

scientific article published on 3 January 2007

Ghrelin and prostate cancer.

scientific article published on January 2008

Ghrelin and synthetic growth hormone secretagogues are cardioactive molecules with identities and differences.

scientific article published in May 2004

Ghrelin and the endocrine pancreas.

scientific article published on October 2003

Ghrelin in fetal thyroid and follicular tumors and cell lines: expression and effects on tumor growth

scientific article published on February 2003

Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans.

scientific article published in October 2002

Ghrelin-producing endocrine tumors of the stomach and intestine

scientific article published on 01 October 2001

Ghrelin: a metabolic signal affecting the reproductive system.

scientific article published on 17 March 2009

Ghrelin: endocrine and non-endocrine actions.

scientific article

Ghrelin: from somatotrope secretion to new perspectives in the regulation of peripheral metabolic functions.

scientific article published on January 2006

Ghrelin: much more than a natural growth hormone secretagogue

scientific article

Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors.

scientific article published on 2 July 2007

Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death.

scientific article published on February 2001

Methodological aspects and pharmacological applications of three-dimensional cancer cell cultures and organoids

scientific article published on 13 May 2020

Modulation of prolactin receptors in the rat hypothalamus in response to changes in serum concentration of endogenous prolactin or to ovine prolactin administration

scientific article published on 01 November 1994

Modulatory effect of prolactin on the DNA synthesis rate and NK activity of large granular lymphocytes.

scientific article published on April 1990

Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation.

scientific article published on October 2002

Natural and synthetic growth hormone secretagogues: do they have therapeutic potential?

scientific article

Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity

scientific article

New active series of growth hormone secretagogues

scientific article published on March 2003

Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans.

scientific article

Normal development of lymphokine activated killing (LAK) in peripheral blood lymphocytes from hyperprolactinemic patients

scientific article published on 01 October 1992

Obestatin affords cardioprotection to the ischemic-reperfused isolated rat heart and inhibits apoptosis in cultures of similarly stressed cardiomyocytes.

scientific article published on 4 June 2010

Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms

scientific article published on 15 October 2012

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

scientific article published on 27 December 2007

Pharmacological and Biochemical Characterization of TLQP-21 Activation of a Binding Site on CHO Cells

scientific article published on 30 March 2017

Physiological and pharmacological variations in rabbit prolactin plasma levels

scientific article published on 01 February 1983

Potentiation of medroxyprogesterone acetate antineoplastic activity by histidine in rat mammary tumours

scientific article published on 01 January 1991

Presence and characterization of prolactin receptors in human benign breast tumours

scientific article published on 01 May 1984

Presence of specific prolactin binding sites in the rabbit hypothalamus

scientific article published on 01 May 1981

Prolactin binding sites in Xenopus laevis tissues: comparison between normal and dehydrated animals.

scientific article published on January 1987

Prolactin binding sites in human erythrocytes and lymphocytes

scientific article published on 01 August 1987

Prolactin receptors in the choroid plexus of non-mammalian and mammalian species

scientific article published on 01 January 1989

Proliferative and protective effects of growth hormone secretagogues on adult rat hippocampal progenitor cells

scientific article published on 24 January 2008

Short ghrelin peptides neither displace ghrelin binding in vitro nor stimulate GH release in vivo

scientific article published in May 2002

Somatostatin, cortistatin and their receptors in tumours.

scientific article published on 08 December 2007

Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland.

scientific article published in April 1998

Targeting the ghrelin receptor: orally active GHS and cortistatin analogs.

scientific article published on October 2003

The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans.

scientific article published in May 2002

The activation of somatostatinergic receptors by either somatostatin-14 or cortistatin-17 often inhibits ACTH hypersecretion in patients with Cushing's disease.

scientific article published in October 2007

The antiproliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells

scientific article published on February 2002

Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats.

scientific article published on 09 April 2010

Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV

scientific article published on 25 December 2020

d-Lys-GHRP-6 does not modify the endocrine response to acylated ghrelin or hexarelin in humans

scientific article published on 16 November 2006