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List of works by Michael M Poe

Abuse-related effects of subtype-selective GABAA receptor positive allosteric modulators in an assay of intracranial self-stimulation in rats

scientific article published in April 2017

Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators

scientific article published on 25 April 2017

An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors

scientific article published on 30 April 2018

Antinociceptive Effects of a Novel α2/α3-Subtype Selective GABAA Receptor Positive Allosteric Modulator

scientific article published on 2 February 2017

Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model

scientific article

Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4 H -benzo[ f ]imidazo [1,5- a ][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABA A receptors: Improved bioavailability enhances anticonvulsant efficacy

scientific article published on 03 May 2018

Characterization of GABAA receptor ligands with automated patch-clamp using human neurons derived from pluripotent stem cells

scientific article published on 17 August 2016

Corrigendum: Regulating anxiety with extrasynaptic inhibition

scientific article published on 01 December 2015

Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments

scientific article published on 27 April 2016

Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit

scientific article

First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development.

scientific article

Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors

scientific article published on 22 April 2017

Mixed Aryl Phosphonate Prodrugs of a Butyrophilin Ligand

scientific article published on 9 August 2017

Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice

scientific article published on 26 January 2018

Neonatal bladder inflammation induces long-term visceral pain and altered responses of spinal neurons in adult rats ⬇️

scientific article published on 23 January 2017

Optimization of substituted imidazobenzodiazepines as novel asthma treatments

scientific article published on 24 November 2016

Pharmacological and antihyperalgesic properties of the novel α2/3 preferring GABAA receptor ligand MP-III-024.

scientific article published on 4 March 2017

Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.

scientific article published on 20 February 2017

Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia

scientific article published on 24 January 2014

Regulating anxiety with extrasynaptic inhibition

scientific article

Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling

scientific article

Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator.

scientific article

Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects

scientific article published on 25 January 2014

Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy

scientific article published on 28 November 2016

The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region

scientific article published on 13 July 2017

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.

scientific article published on 21 March 2016

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