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List of works by Xuedong Liu

A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation

scientific article

A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics.

scientific article published on 5 December 2014

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

scientific article published in July 2000

A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program.

scientific article published on 14 July 2005

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

scientific article

A transcriptional enhancer from the coding region of ADAMTS5

scientific article

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

scientific article

Association of v-ErbA with Smad4 disrupts TGF-beta signaling.

scientific article published on 14 January 2009

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

scientific article

Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment ⬇️

scientific article published on September 30, 2010

Characterization of the DNA-binding property of Smad5.

scientific article published on September 2001

Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins.

scientific article published on 11 June 2015

Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34.

scientific article published on July 2004

Decoding the quantitative nature of TGF-beta/Smad signaling.

scientific article published on 15 August 2008

Dynamics of TGF‐β/Smad signaling ⬇️

scientific article published on April 9, 2012

Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor.

scientific article

Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements

scientific article published on 01 March 1997

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

scientific article

Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration

scientific article published on 31 March 2016

Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers.

scientific article

High-throughput gateway bicistronic retroviral vectors for stable expression in mammalian cells: exploring the biologic effects of STAT5 overexpression

scientific article

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

scientific article

Identification and mechanistic studies of a novel ubiquitin E1 inhibitor.

scientific article

Importin beta mediates nuclear translocation of Smad 3

scientific article (publication date: 4 August 2000)

Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1)

scientific article

Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets

scientific article

Long-term live-cell imaging reveals new roles for Salmonella effector proteins SseG and SteA.

scientific article published on 4 July 2016

Measuring TGF-β Ligand Dynamics in Culture Medium

scientific article published on January 2016

Measuring the absolute abundance of the Smad transcription factors using quantitative immunoblotting.

scientific article

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.

scientific article

Modeling keratinocyte wound healing dynamics: Cell-cell adhesion promotes sustained collective migration.

scientific article published on 19 April 2016

Multi-Omic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines

scientific article published in 2022

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

scientific article published on February 2004

Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy.

scientific article

PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions

scientific article

Partners in crime: the TGFβ and MAPK pathways in cancer progression.

scientific article published on 28 December 2011

Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling

scientific article

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

scientific article published on 05 October 2001

Post-translational modifications as key regulators of TNF-induced necroptosis

scientific article

Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics.

scientific article

Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism

scientific article published on 22 December 2008

Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation

scientific article published on 15 October 2008

Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.

scientific article

Ski/Sno and TGF-beta signaling.

scientific article

Structural and mechanistic insights into Mps1 kinase activation

scientific article

Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase

scientific article published on 26 December 2017

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

scientific article

Systems theory of Smad signalling.

scientific article published in November 2006

The development of a novel high throughput computational tool for studying individual and collective cellular migration

scientific article

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20

scientific article published on 18 March 2019

Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics

scientific article published on 17 February 2009

Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells ⬇️

scientific article published on September 30, 1997

Transforming growth factor-beta induces formation of a dithiothreitol-resistant type I/Type II receptor complex in live cells.

scientific article published on February 1999

Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses.

scientific article published on 15 August 2011

Ubc9 expression is essential for myotube formation in C2C12

scientific article published on 21 April 2006

Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

scientific article published in November 2005

Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.

scientific article published on 24 June 2005

Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT.

scientific article published on 25 October 2006

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