List of works - Giovanna Valenti

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

scientific article published on 18 December 2013

A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle

scientific journal article

A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria.

scientific article

A heterotrimeric G protein of the Gi family is required for cAMP-triggered trafficking of aquaporin 2 in kidney epithelial cells.

scientific article published on August 1998

A new gene-finding tool: using the Caenorhabditis elegans operons for identifying functional partner proteins in human cells

scientific article

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency

scientific article

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

scientific journal article

AQP5 is expressed in type-B intercalated cells in the collecting duct system of the rat, mouse and human kidney.

scientific article published on 14 December 2011

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

scientific article

Adipocytes support cAMP-dependent translocation of aquaporin-2 from intracellular sites distinct from the insulin-responsive GLUT4 storage compartment.

scientific article published on 22 November 2005

Altered Expression of Renal Aquaporins and -Adducin Polymorphisms May Contribute to the Establishment of Salt-Sensitive Hypertension

scientific article published in July 2011

Altered urinary excretion of aquaporin 2 in IgA nephropathy

scientific article published on 08 August 2011

Aquaporin Membrane Channels in Oxidative Stress, Cell Signaling, and Aging: Recent Advances and Research Trends.

scientific article published on 27 March 2018

Aquaporin-2 urinary excretion in preterm infants: relationship to diuresis and vasopressin.

scientific article published on December 2010

Aquaporins, vasopressin, and aging: current perspectives.

scientific article

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

scientific article

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

scientific article published on 22 December 2011

Co-Regulated Pendrin and Aquaporin 5 Expression and Trafficking in Type-B Intercalated Cells under Potassium Depletion

scientific article published on 18 December 2013

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

scientific article

Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance

scientific article

Effect of roscovitine on intracellular calcium dynamics: differential enantioselective responses.

scientific article published on 29 October 2013

Excessive signal transduction of gain-of-function variants of the calcium-sensing receptor (CaSR) are associated with increased ER to cytosol calcium gradient

scientific article

Expression and functional analysis of water channels in a stably AQP2-transfected human collecting duct cell line.

scientific article published on October 1996

Expression and localization of the aquaporin-8 water channel in rat testis

scientific article published on 01 June 2001

Expression of aquaporin-4 in fast-twitch fibers of mammalian skeletal muscle.

scientific article published on August 1998

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells.

scientific article published on December 2004

Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

scientific article published on 20 August 2011

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.

scientific article published on 4 April 2008

Glutathionylation of the aquaporin-2 water channel: a novel post-translational modification modulated by the oxidative stress

scientific article

Histamine treatment induces rearrangements of orthogonal arrays of particles (OAPs) in human AQP4-expressing gastric cells.

scientific article

Hypotonicity Induces Aquaporin-2 Internalization and Cytosol-to-Membrane Translocation of ICln in Renal Cells

scientific article published on 30 November 2006

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

scientific article published on 01 April 2007

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

scientific journal article

In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: a new drug target for hypertension?

scientific article published in January 2012

Influence of bed rest on plasma galanin and adrenomedullin at presyncope.

scientific article published on 15 June 2015

Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.

scientific article published on 17 June 2011

Isolation of frog urinary bladder plasma membranes with polycation coated beads

scientific article published on 01 January 1989

Low-calcium diet in hypercalciuric enuretic children restores AQP2 excretion and improves clinical symptoms.

scientific article published in November 2002

MAL/VIP17, a new player in the regulation of NKCC2 in the kidney

scientific article

Microtubules and actin microfilaments in the amphibian bladder granular cells

scientific article published on 01 January 1989

Minireview: aquaporin 2 trafficking.

scientific article

Phloretin sensitive active urea absorption in frog skin

scientific article published in September 1982

Polarized distribution of Na+/H+ exchanger isoforms in rabbit collecting duct cells ⬇️

scientific article published on May 1, 1998

Regulation of aquaporin-2 trafficking.

scientific article published on January 2009

Regulation of extracellular fluid volume and blood pressure by pendrin.

scientific article

Renal function in space: the link between osteoporosis, hypercalciuria, and aquaporins

scientific article

Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts

scientific journal article

Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans

scientific article published in 2021

Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis.

scientific article published in October 2004

Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells.

scientific article published in August 2003

Small-molecule screening identifies modulators of aquaporin-2 trafficking.

scientific article published on 4 April 2013

Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.

scientific article

The ESF Meeting on „The Proteomics, Epigenetics and Pharmacogenetics of Pendrin“ ⬇️

scientific article published on November 16, 2011

The nature of Cl- secretion, induced by carbaryl, across the isolated skin of Rana esculenta

scientific article published on October 1, 1992

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

scientific article

Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells.

scientific article

Vasopressin, hypercalciuria and aquaporin--the key elements for impaired renal water handling in astronauts?

scientific article published on 01 January 2002

Vasopressin-aquaporin-2 pathway: recent advances in understanding water balance disorders

scientific article published on 04 February 2019

Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

scientific article published on 24 April 2006

cAMP levels and α and β receptors stimulation by noradrenaline in frog skin

scientific article published in January 1983

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.

scientific article published in April 2003

List of works by Giovanna Valenti

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle

A decrease in aquaporin 2 excretion is associated with bed rest induced high calciuria.

A heterotrimeric G protein of the Gi family is required for cAMP-triggered trafficking of aquaporin 2 in kidney epithelial cells.

A new gene-finding tool: using the Caenorhabditis elegans operons for identifying functional partner proteins in human cells

A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency

AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b

AQP5 is expressed in type-B intercalated cells in the collecting duct system of the rat, mouse and human kidney.

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

Adipocytes support cAMP-dependent translocation of aquaporin-2 from intracellular sites distinct from the insulin-responsive GLUT4 storage compartment.

Altered Expression of Renal Aquaporins and -Adducin Polymorphisms May Contribute to the Establishment of Salt-Sensitive Hypertension

Altered urinary excretion of aquaporin 2 in IgA nephropathy

Aquaporin Membrane Channels in Oxidative Stress, Cell Signaling, and Aging: Recent Advances and Research Trends.

Aquaporin-2 urinary excretion in preterm infants: relationship to diuresis and vasopressin.

Aquaporins, vasopressin, and aging: current perspectives.

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins.

Co-Regulated Pendrin and Aquaporin 5 Expression and Trafficking in Type-B Intercalated Cells under Potassium Depletion

Conditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.

Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance

Effect of roscovitine on intracellular calcium dynamics: differential enantioselective responses.

Excessive signal transduction of gain-of-function variants of the calcium-sensing receptor (CaSR) are associated with increased ER to cytosol calcium gradient

Expression and functional analysis of water channels in a stably AQP2-transfected human collecting duct cell line.

Expression and localization of the aquaporin-8 water channel in rat testis

Expression of aquaporin-4 in fast-twitch fibers of mammalian skeletal muscle.

Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells.

Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.

Glutathionylation of the aquaporin-2 water channel: a novel post-translational modification modulated by the oxidative stress

Histamine treatment induces rearrangements of orthogonal arrays of particles (OAPs) in human AQP4-expressing gastric cells.

Hypotonicity Induces Aquaporin-2 Internalization and Cytosol-to-Membrane Translocation of ICln in Renal Cells

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: a new drug target for hypertension?

Influence of bed rest on plasma galanin and adrenomedullin at presyncope.

Integrin signaling modulates AQP2 trafficking via Arg-Gly-Asp (RGD) motif.

Isolation of frog urinary bladder plasma membranes with polycation coated beads

Low-calcium diet in hypercalciuric enuretic children restores AQP2 excretion and improves clinical symptoms.

MAL/VIP17, a new player in the regulation of NKCC2 in the kidney

Microtubules and actin microfilaments in the amphibian bladder granular cells

Minireview: aquaporin 2 trafficking.

Phloretin sensitive active urea absorption in frog skin

Polarized distribution of Na+/H+ exchanger isoforms in rabbit collecting duct cells ⬇️

Regulation of aquaporin-2 trafficking.

Regulation of extracellular fluid volume and blood pressure by pendrin.

Renal function in space: the link between osteoporosis, hypercalciuria, and aquaporins

Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts

Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans

Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis.

Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells.

Small-molecule screening identifies modulators of aquaporin-2 trafficking.

Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.

The ESF Meeting on „The Proteomics, Epigenetics and Pharmacogenetics of Pendrin“ ⬇️

The nature of Cl- secretion, induced by carbaryl, across the isolated skin of Rana esculenta

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

Trafficking and phosphorylation dynamics of AQP4 in histamine-treated human gastric cells.

Vasopressin, hypercalciuria and aquaporin--the key elements for impaired renal water handling in astronauts?

Vasopressin-aquaporin-2 pathway: recent advances in understanding water balance disorders

Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

cAMP levels and α and β receptors stimulation by noradrenaline in frog skin

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.