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List of works by Anne I Sperling

Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses

scientific article published on 07 August 2020

Advancing Science Through Collaborative Data Sharing and Synthesis

scientific article (publication date: July 2013)

Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation

scientific article published on 30 October 2018

Amish and Hutterite Environmental Farm Products Have Opposite Effects on Experimental Models of Asthma

scientific article published on March 2016

Antigen stimulation of TH2 cells augments acute bacterial sinusitis in mice

scientific article published on 01 August 2004

Associations between fungal and bacterial microbiota of airways and asthma endotypes

scientific article published on 03 July 2019

Autoreactive T and B cells induce the development of bronchus-associated lymphoid tissue in the lung

scientific article published on April 2013

CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo.

scientific article published on 10 July 2009

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation ⬇️

scientific article published on February 2, 2011

CD43 modulates severity and onset of experimental autoimmune encephalomyelitis

scientific article published on 01 December 2003

CD43 regulates Th2 differentiation and inflammation

scientific article published on June 2008

CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism

scientific journal article

CTLA4Ig Inhibits Airway Eosinophilia and Hyperresponsiveness by Regulating the Development of Th1/Th2 Subsets in a Murine Model of Asthma ⬇️

scientific article published on April 1, 1998

Circulating Plasma Biomarkers of Progressive Interstitial Lung Disease

scientific article published on 01 January 2020

Circulating Plasma Biomarkers of Survival in Anti-fibrotic Treated Patients with Idiopathic Pulmonary Fibrosis

scientific article published on 22 May 2020

Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease

scientific article published on 4 February 2013

Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways.

scientific article published on 25 November 2015

Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation

scientific article published in February 2003

Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production

scientific article

DNA methylation in lung cells is associated with asthma endotypes and genetic risk

scientific article published on 08 December 2016

DNA-directed assembly of antibody-fluorophore conjugates for quantitative multiparametric flow cytometry

scientific article published on 27 December 2013

Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome

scientific article published on September 2010

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

scientific article

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity

scientific article

Distinct T-helper cell responses to Staphylococcus aureus bacteremia reflect immunologic comorbidities and correlate with mortality

scientific article published on 25 April 2018

Distinct dendritic cell subsets actively induce Th2 polarization

scientific article

Dynamic migration of γδ intraepithelial lymphocytes requires occludin

scientific article

Editorial overview: Allergy and hypersensitivity

scientific article published on 01 December 2014

Effects of an FcγRIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies

scientific article published on 06 July 2018

Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma.

scientific article

Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry

scientific article published on 25 April 2019

Expression of Fas (CD95) and FasL (CD95L) in Human Airway Epithelium ⬇️

scientific article published on October 1, 1998

Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice

scientific article

Fas ligand expression on T cells is sufficient to prevent prolonged airway inflammation in a murine model of asthma.

scientific article

Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma

scientific article

Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization

scientific article published on 26 August 2020

Gata5 deficiency causes airway constrictor hyperresponsiveness in mice.

scientific article

Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness

scientific article published on January 2008

Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways

scientific article published on 16 October 2015

ICOS costimulation expands Th2 immunity by augmenting migration of lymphocytes to draining lymph nodes

scientific article published on July 2008

ICOS costimulation: is it the key to selective immunotherapy?

scientific article published on 01 September 2001

ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection

scientific article

IL-33 Drives Monocyte Recruitment to Lung Interstitium through Chemokine Upregulation

scientific article published on 15 August 2017

IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.

scientific article published on 15 April 2013

Immune development and environment: lessons from Amish and Hutterite children

scientific article

Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report

scientific article published on 01 August 2019

Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L

scientific article published on 18 March 2011

Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells

scientific article

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

scientific article

Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice.

scientific article published on 23 October 2015

Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents

scientific article published in 2022

Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation.

scientific article

Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells

scientific article

Maternal asthma and microRNA regulation of soluble HLA-G in the airway

scientific article published on 25 March 2013

NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses

scientific article

Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation

scientific article published on 01 November 2018

Non-classical MHC molecules: the first line of defence?

scientific article published on 01 May 1993

PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod

scientific article (publication date: 2013)

Preexisting Type 2 Immune Activation Protects against the Development of Sepsis

scientific article published in November 2017

Pro-lymphangiogenic VEGFR-3 signaling modulates memory T cell responses in allergic airway inflammation

scientific article published on 09 June 2020

Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment. An Observational Cohort Study with Independent Validation

scientific article published on 01 March 2019

Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils

scientific article published on 21 March 2019

Protective effector memory CD4 T cells depend on ICOS for survival

scientific article

Quantitation of secretory group V phospholipase A(2) in human tissues by sandwich enzyme-linked immunosorbent assay.

scientific article

RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation

scientific article published on 27 September 2013

Regulation of Smad-mediated gene transcription by RGS3.

scientific article published on 20 February 2008

Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease?

scientific article (publication date: October 2006)

Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin

scientific article published on 12 April 2013

Reply to Lescoat et al. and to Khamis et al

scientific article published on 01 April 2019

Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma

scientific article

Role of type 1 T helper cells in the resolution of acute Streptococcus pneumoniae sinusitis: a mouse model

scientific article published on 26 August 2005

Signaling through CD43 regulates CD4 T-cell trafficking

scientific article

Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation.

scientific article

Signaling through FcRγ-associated receptors on dendritic cells drives IL-33-dependent TH2-type responses.

scientific article

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

scientific article published on 01 June 2019

Single-Cell Transcriptomic Analysis of Human Lung Reveals Complex Multicellular Changes During Pulmonary Fibrosis

article

Skewed Lung CCR4 to CCR6 CD4+ T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function

scientific article

T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival

scientific article published on 01 February 2019

T-cell costimulation blockade in immunologic diseases: role of CD28 family members

scientific article published on May 2007

T-cell phenotypes are associated with serum IgE levels in Amish and Hutterite children

scientific article published on 08 August 2019

Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis

scientific article published on 17 September 2020

The clinical and immunologic features of pulmonary fibrosis in sarcoidosis

scientific article published on 10 April 2012

The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation

scientific article

The distal pole complex: a novel membrane domain distal to the immunological synapse

scientific article published in November 2002

The role of dendritic cells and monocytes in the maintenance and loss of respiratory tolerance

scientific article

Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.

scientific article published on January 2013

Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells

scientific article published on 13 November 2019

γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice

scientific article

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