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List of works by Ayaz Najafov

ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner

scientific article published on 19 October 2018

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.

scientific article published on 4 December 2017

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation

scientific article published on 20 April 2021

Activation of necroptosis in multiple sclerosis

scientific article published in March 2015

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors

scientific article

Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.

scientific article published on 9 June 2010

Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3

scientific article published on 04 December 2019

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1.

scientific article published in January 2011

Clinicopathological and genetic study of early-onset demyelinating neuropathy.

scientific article published on 6 October 2004

Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.

scientific article published on 21 March 2016

CrossCheck: an open-source web tool for high-throughput screen data analysis

scientific article published on 19 July 2017

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

scientific article

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L

scientific article published on 30 March 2015

MENA is a transcriptional target of the Wnt/beta-catenin pathway

scientific article published on 17 May 2012

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

scientific article published on 21 July 2021

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis

scientific article published on 23 September 2020

Necroptosis and Cancer.

scientific article

Necroptosis in development and diseases.

scientific article

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model

scientific article published on 12 November 2020

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

scientific article

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

scientific article published on 25 August 2017

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.

scientific article published on 11 June 2018

Roles of Caspases in Necrotic Cell Death.

scientific article published on December 2016

Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death

scientific article

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids

scientific article

The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans

scientific article

Uncoupling the Warburg effect from cancer

scientific article

ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase

scientific article

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