List of works - Tatsuya Kondo

A case of ectopic adrenocorticotropic hormone-producing pancreatic neuroendocrine tumor with multiple liver metastases

scientific article published on 22 December 2009

A case of hyperinsulinemia of undetermined origin, successfully treated with long-acting octreotide.

scientific article

A case of primary thyroid squamous cell cancer: transformation from benign tumour associated with chronic thyroiditis?

scientific article

A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications

scientific article published on December 2009

AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.

scientific article published on March 2005

Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice.

scientific article published on 8 September 2016

Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial.

scientific article published on 19 October 2016

Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.

scientific article

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

scientific article

Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.

scientific article published on 3 May 2006

Altered insulin signaling in retinal tissue in diabetic states

scientific article

An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice.

scientific article published on 17 August 2010

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis

scientific article

Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice

scientific article published on 28 April 2011

Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages.

scientific article published on 11 January 2013

Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes

scientific article published on 27 December 2013

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice

scientific article

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

scientific article

Clinical features of insulinoma in patients with multiple endocrine neoplasia type 1: analysis of the database of the MEN Consortium of Japan

scientific article published on 16 June 2012

Comparison of the efficacy of sitagliptin and glimepiride dose-up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination.

scientific article

Defective smooth muscle development in qkI-deficient mice

scientific journal article

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

article

Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.

scientific article published on 4 November 2013

Efficacy and safety of sitagliptin as add-on therapy on glycemic control and blood glucose fluctuation in Japanese type 2 diabetes subjects ongoing with multiple daily insulin injections therapy

scientific article published on 3 August 2013

Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice.

scientific article

Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.

scientific article published in February 2005

Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

scientific article published on 18 December 2010

Heat shock response regulates insulin sensitivity and glucose homeostasis: pathophysiological impact and therapeutic potential.

scientific article published on July 2011

Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjects

scientific article published on 01 April 2010

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice

scientific article published on 07 June 2007

Hyperthermia with mild electrical stimulation protects pancreatic β-cells from cell stresses and apoptosis.

scientific article published on 23 February 2012

IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance

scientific article published on 12 October 2007

Identification of microRNA that represses IRS-1 expression in liver.

scientific article

Impact of hepatic HSP72 on insulin signaling

scientific article published on 11 December 2018

Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes

scientific article published on 01 August 2018

Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress

scientific article published in February 2013

Intraoperative Scoring System to Predict Postoperative Remission in Endoscopic Endonasal Transsphenoidal Surgery for Growth Hormone-Secreting Pituitary Adenomas

scientific article

Japanese Clinical Practice Guideline for Diabetes 2016

scientific article published on 01 February 2018

Japanese Clinical Practice Guideline for Diabetes 2016.

scientific article published on 26 March 2018

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization

scientific article

Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.

scientific article published in April 2004

Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials

scientific article published on 11 November 2014

Mild electrical stimulation increases stress resistance and suppresses fat accumulation via activation of LKB1-AMPK signaling pathway in C. elegans

scientific article

Mild electrical stimulation increases ubiquitinated proteins and Hsp72 in A549 cells via attenuation of proteasomal degradation.

scientific article published on 10 October 2008

Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling

scientific article

New glycemic targets for patients with diabetes from the Japan Diabetes Society

scientific article published on 09 December 2016

New glycemic targets for patients with diabetes from the Japan Diabetes Society.

scientific article

Nucleotide sequence of complementary DNA encoding for quaking protein of cow, horse and pig

scholarly article

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

scholarly article

Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.

scientific article published in April 2010

Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice

scientific article published on 27 December 2012

Regulation of insulin signaling and its disorder

scientific article

Role for neuronal insulin resistance in neurodegenerative diseases

scholarly article

Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues.

scientific article published on 19 September 2008

Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation

scientific article

Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation

scientific article published on 19 December 2014

Sudden onset of diabetes with ketoacidosis in a patient treated with FK506/tacrolimus

scientific article published in April 2002

Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms.

scientific article

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

scientific journal article

The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report

scientific article published on 30 January 2018

The impact of Ca²⁺/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells.

scientific article published on 25 April 2012

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

scientific article published on 8 June 2010

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

scientific article

The role of heat shock response in insulin resistance and diabetes.

scientific article published on April 2014

The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.

scientific article

List of works by Tatsuya Kondo

A case of ectopic adrenocorticotropic hormone-producing pancreatic neuroendocrine tumor with multiple liver metastases

A case of hyperinsulinemia of undetermined origin, successfully treated with long-acting octreotide.

A case of primary thyroid squamous cell cancer: transformation from benign tumour associated with chronic thyroiditis?

A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications

AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells.

Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice.

Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial.

Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake

Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.

Altered insulin signaling in retinal tissue in diabetic states

An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice.

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis

Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice

Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages.

Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

Clinical features of insulinoma in patients with multiple endocrine neoplasia type 1: analysis of the database of the MEN Consortium of Japan

Comparison of the efficacy of sitagliptin and glimepiride dose-up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination.

Defective smooth muscle development in qkI-deficient mice

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.

Efficacy and safety of sitagliptin as add-on therapy on glycemic control and blood glucose fluctuation in Japanese type 2 diabetes subjects ongoing with multiple daily insulin injections therapy

Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice.

Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.

Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

Heat shock response regulates insulin sensitivity and glucose homeostasis: pathophysiological impact and therapeutic potential.

Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjects

High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice

Hyperthermia with mild electrical stimulation protects pancreatic β-cells from cell stresses and apoptosis.

IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance

Identification of microRNA that represses IRS-1 expression in liver.

Impact of hepatic HSP72 on insulin signaling

Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes

Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress

Intraoperative Scoring System to Predict Postoperative Remission in Endoscopic Endonasal Transsphenoidal Surgery for Growth Hormone-Secreting Pituitary Adenomas

Japanese Clinical Practice Guideline for Diabetes 2016

Japanese Clinical Practice Guideline for Diabetes 2016.

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization

Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.

Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials

Mild electrical stimulation increases stress resistance and suppresses fat accumulation via activation of LKB1-AMPK signaling pathway in C. elegans

Mild electrical stimulation increases ubiquitinated proteins and Hsp72 in A549 cells via attenuation of proteasomal degradation.

Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling

New glycemic targets for patients with diabetes from the Japan Diabetes Society

New glycemic targets for patients with diabetes from the Japan Diabetes Society.

Nucleotide sequence of complementary DNA encoding for quaking protein of cow, horse and pig

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.

Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice

Regulation of insulin signaling and its disorder

Role for neuronal insulin resistance in neurodegenerative diseases

Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues.

Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation

Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation

Sudden onset of diabetes with ketoacidosis in a patient treated with FK506/tacrolimus

Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms.

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report

The impact of Ca²⁺/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells.

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

The role of heat shock response in insulin resistance and diabetes.

The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.