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List of works by Machteld N Hylkema

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers

scientific article

Adenosine receptors in COPD and asymptomatic smokers: effects of smoking cessation

scientific article published on 23 January 2009

Airway epithelial changes in smokers but not in ex-smokers with asthma

scientific article published on October 2009

Are there reasons why adult asthma is more common in females?

scientific article published on May 2007

Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study

scientific article published on 28 January 2013

Authors’ response to Persson C: primary lysis/necrosis of eosinophils and clinical control of asthma

scientific article published in March 2013

Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?

scientific article

Characterization of macrophage phenotypes in three murine models of house-dust-mite-induced asthma

scientific article published on 27 February 2013

Cigarette smoke-induced emphysema: A role for the B cell?

scientific article

Clinical control of asthma associates with measures of airway inflammation

scientific article published on 6 October 2012

Differential switching to IgG and IgA in active smoking COPD patients and healthy controls.

scientific article published on 12 January 2012

Dual role of YM1+ M2 macrophages in allergic lung inflammation.

scientific article published on 23 March 2018

Effects of IL-4 and IL-13 on adenosine receptor expression and responsiveness of the human mast cell line 1.

scientific article

Epiproteome profiling of cadmium-transformed human bronchial epithelial cells by quantitative histone post-translational modification-enzyme-linked immunosorbent assay.

scientific article published on 9 February 2018

Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?

scientific article

Heparan Sulfate Staining of the Glomerular Basement Membrane in Relation to Circulating Anti-DNA and Anti-Heparan Sulfate Reactivity: a Longitudinal Study in NZB/W F1 Mice

scientific article published on 01 February 1996

Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue

scientific article published on 12 February 2020

INTRATHYMIC IMMUNE MODULATION PREVENTS ACUTE REJECTION BUT NOT THE DEVELOPMENT OF GRAFT ARTERIOSCLEROSIS (CHRONIC REJECTION)1

article

Increased levels of (class switched) memory B cells in peripheral blood of current smokers

scientific article published on 12 November 2009

Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice

scientific article

Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.

scientific article

More alternative activation of macrophages in lungs of asthmatic patients

scientific article published on 17 December 2010

Nitrogen Dioxide Exposure Attenuates Cigarette Smoke-Induced Cytokine Production in Mice

article

Old dilemma: asthma with irreversible airway obstruction or COPD.

scientific article

Persisting Remodeling and Less Airway Wall Eosinophil Activation in Complete Remission of Asthma

article by Martine Broekema et al published February 2011 in American Journal of Respiratory and Critical Care Medicine

Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant <i>Cyp2a5</i> Methylation

scientific article published on 26 December 2020

Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring.

scientific article published on 27 January 2017

Prenatal smoke effect on mouse offspring Igf1 promoter methylation from fetal stage to adulthood is organ and sex specific

scientific article published on 08 January 2020

Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring

scientific article published on 23 June 2020

Repeated Sputum Inductions Induce a Transient Neutrophilic and Eosinophilic Response

article

Short-term smoke exposure attenuates ovalbumin-induced airway inflammation in allergic mice.

scientific article

Single Expression of CD45RC and RT6 in Correlation with T-Helper 1 and T-Helper 2 Cytokine Patterns in the Rat

scientific article published on 01 February 2000

Smoking and nonsmoking asthma: differences in clinical outcome and pathogenesis

scientific article published on February 2011

Smoking during pregnancy influences the maternal immune response in mice and humans.

scientific article published on 16 April 2012

Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells.

scientific article published on 23 December 2016

The fetal programming effect of prenatal smoking on Igf1r and Igf1 methylation is organ- and sex-specific

scientific article

Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells

scientific article published on 10 October 2020