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List of works by Sundarasamy Mahalingam

A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopes

scientific article published on 23 August 2008

A non-canonical transferable signal mediates nuclear import of simian immunodeficiency virus Vpx protein.

scientific article published in August 2003

A novel lysine-rich domain and GTP binding motifs regulate the nucleolar retention of human guanine nucleotide binding protein, GNL3L.

scientific article

Antigenicity and immunogenicity of a trimeric envelope protein from an Indian clade C HIV-1 isolate

scientific article published on 17 February 2015

Attenuated nef DNA vaccine construct induces cellular immune response: role in HIV-1 multiprotein vaccine.

scientific article published on October 2003

Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques

scientific article

Cytosine methylation by DNMT2 facilitates stability and survival of HIV-1 RNA in the host cell during infection.

scientific article published on 5 May 2017

Development of genetic vaccines for pathogenic genes: construction of attenuated vif DNA immunization cassettes.

scientific article published on October 1997

Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

scientific article published on 01 July 1997

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

scientific article published in October 1995

Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.

scientific article

Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation

scientific article

GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation.

scientific article published on 14 August 2015

HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G 2 /M phase transition of the mammalian cell cycle

scientific article published on March 31, 1998

HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B.

scientific article published on October 1997

HIV-1 Vpr transactivates LTR-directed expression through sequences present within -278 to -176 and increases virus replication in vitro.

scientific article

HIV-1 Vpr: a closer look at the multifunctional protein from the structural perspective.

scientific article published on March 2009

Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation

scientific article published on 01 February 1995

Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-κB) signaling during cell proliferation.

scientific article published on 20 October 2016

Mechanism of Host Cell MAPK/ERK-2 Incorporation into Lentivirus Particles: Characterization of the Interaction between MAPK/ERK-2 and Proline-Rich-Domain Containing Capsid Region of Structural Protein Gag

scientific article published on July 22, 2011

Membrane bound Indian clade C HIV-1 envelope antigen induces antibodies to diverse and conserved epitopes upon DNA prime/protein boost in rabbits.

scientific article published on 28 March 2016

Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model

scientific article

Nuclear export of simian immunodeficiency virus Vpx protein.

scientific article published on 20 September 2006

Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals.

scientific article

Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1.

scientific article

Proteomic analysis reveals modulation of iron homeostasis and oxidative stress response in Pseudomonas aeruginosa PAO1 by curcumin inhibiting quorum sensing regulated virulence factors and biofilm production.

scientific article published on 19 April 2016

RNA-seq reveals outcome-specific gene expression of MMP7 and PCK1 in biliary atresia

scientific article published on 24 July 2019

Role of the conserved dipeptide Gly75 and Cys76 on HIV-1 Vpr function

scientific article published on 01 July 1995

Signals and pathways regulating nucleolar retention of novel putative nucleolar GTPase NGP-1(GNL-2).

scientific article

Subcellular distribution of the human putative nucleolar GTPase GNL1 is regulated by a novel arginine/lysine-rich domain and a GTP binding domain in a cell cycle-dependent manner.

scientific article published on 5 January 2012

The carboxy-terminal domain is essential for stability and not for virion incorporation of HIV-1 Vpr into virus particles.

scientific article

The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA.

scientific article

The non-enzymatic RAS effector RASSF7 inhibits oncogenic c-Myc function

scientific article published in Journal of Biological Chemistry

Vanillic acid from Actinidia deliciosa impedes virulence in Serratia marcescens by affecting S-layer, flagellin and fatty acid biosynthesis proteins.

scientific article published on 27 November 2017