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List of works by Andrew Koff

Application of molecular biology to individualize therapy for patients with liposarcoma.

scientific article published on January 2015

CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis

scientific journal article

Cdk pathway: cyclin-dependent kinases and cyclin-dependent kinase inhibitors

scientific article published on 01 October 2001

Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cells

scientific article published in Journal of Biological Chemistry

Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin

scientific article

Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor.

scientific article published on June 1999

Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.

scientific article

Cyclin D1 and Cdk4 Mediate Development of Neurologically Destructive Oligodendroglioma ⬇️

scientific article published on August 15, 2011

Cyclin-dependent kinase inhibitors in restriction point control, genomic stability, and tumorigenesis

scientific article published on 01 January 1998

Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas.

scientific article

Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma

scientific article published on 01 September 1998

Ectopic expression of p27Kip1 in oligodendrocyte progenitor cells results in cell-cycle growth arrest ⬇️

scientific article published on September 5, 1998

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

scientific article published on March 1997

Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate

scientific article

Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer

scientific article published on 01 December 1997

Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis.

scientific article published on August 2006

Glomerular aging in females is a multi-stage reversible process mediated by phenotypic changes in progenitors.

scientific article

How to decrease p27Kip1 levels during tumor development

scientific article published on 01 February 2006

Increased number of multi-oocyte follicles (MOFs) in juvenile p27Kip1 mutant mice: potential role of granulosa cells

scientific article published on 8 January 2013

Inhibin and p27 interact to regulate gonadal tumorigenesis.

scientific article published in June 2001

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.

scientific article published on April 2015

Misexpression of cyclin B3 leads to aberrant spermatogenesis.

scientific article published in September 2006

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1 ⬇️

scientific article published on September 15, 1997

Overview of the cell cycle

scientific article published on 01 May 2001

PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells.

scientific article published on 14 May 2005

Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.

scientific article published on 28 April 2016

Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence

scientific article published on 01 November 1999

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

scientific article published on 01 February 2001

Regulation of the cell cycle by CDK inhibitors ⬇️

scientific article published on January 1, 1998

Regulatory role of p27kip1 in the mouse and human testis

scientific article published on 01 April 1999

Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status.

scientific article published on March 2002

Roles of cyclin-dependent kinase inhibitors: lessons from knockout mice.

scientific article published on January 1998

The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.

scientific article

The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity

scientific journal article

The absence of p27Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouples differentiation and growth arrest during the granulosa->luteal transition

scientific article published on 01 September 1998

The cell cycle regulator p27kip1 contributes to growth and differentiation of osteoblasts.

scientific article published in August 1999

The zinc finger gene ZIC2 has features of an oncogene and its overexpression correlates strongly with the clinical course of epithelial ovarian cancer

scientific article

Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.

scientific article

p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.

scientific article

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

scientific article published on May 1999

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

scientific article

p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation

scientific article

p53 regulates hematopoietic stem cell quiescence.

scientific article

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