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List of works by Megan J Smithey

Acute systemic DNA damage in youth does not impair immune defense with aging

scientific article

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

scientific article

Age-related changes in CD8 T cell homeostasis and immunity to infection

scientific article

Cutting Edge: The Aging Immune System Reveals the Biological Impact of Direct Antigen Presentation on CD8 T Cell Responses

scientific article published on 14 June 2017

Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection

scientific article

Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections

scientific article

Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice

scientific article

Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life

scientific article

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

scientific article

Lost in translation: mice, men and cutaneous immunity in old age.

scientific article published on 16 July 2014

New advances in CMV and immunosenescence

scientific article

Stimulation of enhanced CD8 T cell responses following immunization with a hyper-antigen secreting intracytosolic bacterial pathogen.

scientific article