List of works - Chris Corrigan

"Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation.

scientific article

Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes.

scientific article published on 11 February 2016

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

scientific article published on 13 May 2011

AllergoOncology - the impact of allergy in oncology: EAACI position paper.

scientific article published on 29 December 2016

An annexin 1 (ANXA1)-derived peptide inhibits prototype antigen-driven human T cell Th1 and Th2 responses in vitro.

scientific article published in July 2001

Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1

scientific article published on 26 May 2015

Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

scientific article published on 17 January 2017

Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cells

scientific article (publication date: February 2006)

Assessment of specific immunotherapy efficacy using a novel placebo score-based method

scientific article published on 01 November 2012

Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial

scientific article published on 19 September 2016

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

scientific article published on 07 July 2020

Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

scientific article

Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells

scientific article published on September 2017

Cigarette smoking increases bronchial mucosal IL-17A expression in asthmatics, which acts in concert with environmental aeroallergens to engender neutrophilic inflammation

scientific article published on 17 February 2017

Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma

scientific article published on 01 January 2007

Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics.

scientific article published on December 1998

Counter regulation of the high affinity IgE receptor, FcepsilonRI, on human airway dendritic cells by IL-4 and IL-10.

scientific article published on 6 April 2009

Direct comparison of the dynamics of IL-25- and 'allergen'-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

scientific article published on 01 January 2014

Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol

scientific article

Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs).

scientific article

Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects

article

Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD.

scientific article published on 20 December 2007

Eph and NMDA receptors control Ca2+/calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation.

scientific article published on 2 November 2005

Epidemiological associations of allergy, IgE and cancer.

scientific article published on October 2013

Expression of prostaglandin E(2) receptor subtypes on cells in sputum from patients with asthma and controls: effect of allergen inhalational challenge.

scientific article published in December 2004

Farewell.

scientific article published in December 2015

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

scientific article published on 16 May 2011

IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-gamma expression

scientific article published on 01 May 1997

IL-4–expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR3 and CCR4

scientific article published in September 2005

IL-5 production by allergen-stimulated T cells following grass pollen immunotherapy for seasonal allergic rhinitis

scientific article published on 01 October 1997

IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease

scientific article published in April 1997

Imaging Inflammation in Asthma: Real Time, Differential Tracking of Human Neutrophil and Eosinophil Migration in Allergen Challenged, Atopic Asthmatics in Vivo.

scientific article published on 28 October 2014

Immunotherapy for allergic rhinitis.

scientific article

Increased prevalence of gastrointestinal symptoms in patients with allergic disease.

scientific article published on March 2007

Inhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal?

scientific article published on 31 December 2019

Inhaled corticosteroid dose-response on blood eosinophils in asthma - Authors' reply.

scientific article

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT)

scientific article

Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists.

scientific article

Interleukin-25 promotes basic fibroblast growth factor expression by human endothelial cells through interaction with IL-17RB, but not IL-17RA

scientific article published on 01 November 2012

Lack of filaggrin expression in the human bronchial mucosa

scientific article published on 13 October 2006

Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis

scientific article (publication date: 7 November 2002)

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

scientific article published on 12 January 2009

Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge

scientific article published in October 2011

Mechanism of glucocorticoid action in asthma: too little, too late

scientific article published on March 1, 1992

Mechanisms of intrinsic asthma

scientific article published on February 2004

Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition.

scientific article published in August 2003

Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy.

scientific article published in May 2005

Monocytes and macrophages - friend or foe?

Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

scientific article published on 4 November 2016

Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

scientific article published in February 2017

Real-life comparison of beclometasone dipropionate as an extrafine- or larger-particle formulation for asthma

scientific article published in July 2013

Real-time differential tracking of human neutrophil and eosinophil migration in vivo.

scientific article published on 13 August 2013

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application.

scientific article published on 03 December 2011

Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma

scientific article published on 13 March 2012

Relationship between IL-4 and IL-5 mRNA Expression and Disease Severity in Atopic Asthma

scientific article published in September 1997

Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.

scientific article published on May 2015

Resistin-like molecule-β is a human airway remodelling mediator.

scientific article

Retail sales of inhalation devices in European countries: so much for a global policy.

scientific article published on 13 April 2011

Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

scientific article

Rhinitis associated with asthma is distinct from rhinitis alone: The <scp>ARIA‐MeDALL</scp> hypothesis

scientific article published in 2023

Role of cysteinyl leukotrienes in human allergen-specific Th2 responses induced by granulocyte macrophage-colony stimulating factor

scientific article

Secretion of the eosinophil‐active cytokines interleukin‐5, granulocyte/macrophage colonystimulating factor and interleukin‐3 by bronchoalveolar lavage CD4+ and CD8+ T cell lines in atopics asthmatics, and atopic and nonatopic controls ⬇️

scientific article published on October 1, 1995

Serum 25-dihydroxyvitamin D levels correlate with CD4+Foxp3+ T-cell numbers in moderate/severe asthma

scientific article published on 30 May 2012

Special issue on severe asthma

scientific article published on 20 April 2012

Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

scientific article

Sublingual immunotherapy

scientific article published on 21 December 2006

Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients

scientific article published on 27 June 2006

T cells from human allergen-induced late asthmatic responses express IL-12 receptor beta 2 subunit mRNA and respond to IL-12 in vitro

scientific article published on 01 September 2000

T cells producing the anti-inflammatory cytokine IL-10 regulate allergen-specific Th2 responses in human airways

article

T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma

scientific article

The effects of calcitriol treatment in glucocorticoid-resistant asthma

scientific article published on 29 April 2014

The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients

scientific article published in December 2001

Unstimulated basophils in atopic and nonatopic subjects express intracellular interleukin-4: detection by flow cytometry

scientific article published on 01 September 1998

Urban Particulate Matter-Activated Human Dendritic Cells Induce the Expansion of Potent Inflammatory Th1, Th2, and Th17 Effector Cells.

scientific article published on 21 July 2015

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

scientific article published on 12 November 2014

List of works by Chris Corrigan

"Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation.

Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes.

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

AllergoOncology - the impact of allergy in oncology: EAACI position paper.

An annexin 1 (ANXA1)-derived peptide inhibits prototype antigen-driven human T cell Th1 and Th2 responses in vitro.

Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1

Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cells

Assessment of specific immunotherapy efficacy using a novel placebo score-based method

Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells

Cigarette smoking increases bronchial mucosal IL-17A expression in asthmatics, which acts in concert with environmental aeroallergens to engender neutrophilic inflammation

Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma

Costimulation through CD86 is involved in airway antigen-presenting cell and T cell responses to allergen in atopic asthmatics.

Counter regulation of the high affinity IgE receptor, FcepsilonRI, on human airway dendritic cells by IL-4 and IL-10.

Direct comparison of the dynamics of IL-25- and 'allergen'-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol

Double-blind randomised placebo-controlled trial of bolus-dose vitamin D3 supplementation in adults with asthma (ViDiAs).

Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects

Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD.

Eph and NMDA receptors control Ca2+/calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation.

Epidemiological associations of allergy, IgE and cancer.

Expression of prostaglandin E(2) receptor subtypes on cells in sputum from patients with asthma and controls: effect of allergen inhalational challenge.

Farewell.

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-gamma expression

IL-4–expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR3 and CCR4

IL-5 production by allergen-stimulated T cells following grass pollen immunotherapy for seasonal allergic rhinitis

IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease

Imaging Inflammation in Asthma: Real Time, Differential Tracking of Human Neutrophil and Eosinophil Migration in Allergen Challenged, Atopic Asthmatics in Vivo.

Immunotherapy for allergic rhinitis.

Increased prevalence of gastrointestinal symptoms in patients with allergic disease.

Inhaled Corticosteroids Prescribed for COPD Patients with Mild or Moderate Airflow Limitation: Who Warrants a Trial of Withdrawal?

Inhaled corticosteroid dose-response on blood eosinophils in asthma - Authors' reply.

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT)

Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists.

Interleukin-25 promotes basic fibroblast growth factor expression by human endothelial cells through interaction with IL-17RB, but not IL-17RA

Lack of filaggrin expression in the human bronchial mucosa

Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge

Mechanism of glucocorticoid action in asthma: too little, too late

Mechanisms of intrinsic asthma

Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition.

Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy.

Monocytes and macrophages - friend or foe?

Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

Real-life comparison of beclometasone dipropionate as an extrafine- or larger-particle formulation for asthma

Real-time differential tracking of human neutrophil and eosinophil migration in vivo.

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application.

Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma

Relationship between IL-4 and IL-5 mRNA Expression and Disease Severity in Atopic Asthma

Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.

Resistin-like molecule-β is a human airway remodelling mediator.

Retail sales of inhalation devices in European countries: so much for a global policy.

Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

Rhinitis associated with asthma is distinct from rhinitis alone: The <scp>ARIA‐MeDALL</scp> hypothesis

Role of cysteinyl leukotrienes in human allergen-specific Th2 responses induced by granulocyte macrophage-colony stimulating factor

Secretion of the eosinophil‐active cytokines interleukin‐5, granulocyte/macrophage colonystimulating factor and interleukin‐3 by bronchoalveolar lavage CD4+ and CD8+ T cell lines in atopics asthmatics, and atopic and nonatopic controls ⬇️

Serum 25-dihydroxyvitamin D levels correlate with CD4+Foxp3+ T-cell numbers in moderate/severe asthma

Special issue on severe asthma

Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

Sublingual immunotherapy

Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients

T cells from human allergen-induced late asthmatic responses express IL-12 receptor beta 2 subunit mRNA and respond to IL-12 in vitro

T cells producing the anti-inflammatory cytokine IL-10 regulate allergen-specific Th2 responses in human airways

T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma

The effects of calcitriol treatment in glucocorticoid-resistant asthma

The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients

Unstimulated basophils in atopic and nonatopic subjects express intracellular interleukin-4: detection by flow cytometry

Urban Particulate Matter-Activated Human Dendritic Cells Induce the Expansion of Potent Inflammatory Th1, Th2, and Th17 Effector Cells.

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.