List of works - Shinsuke Niwa

A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability.

scientific article

A molecular motor, KIF13A, controls anxiety by transporting the serotonin type 1A receptor.

scientific article published on 8 February 2013

Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.

scientific article

BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.

scientific article

Characterizing KIF16B in neurons reveals a novel intramolecular "stalk inhibition" mechanism that regulates its capacity to potentiate the selective somatodendritic localization of early endosomes.

scientific article

Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

scientific article published on 27 August 2019

Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons

scientific article published on 18 October 2017

KIF19A is a microtubule-depolymerizing kinesin for ciliary length control

scientific journal article

KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.

scientific article

KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth

scientific article published on 20 August 2018

Kinesin superfamily proteins and the regulation of microtubule dynamics in morphogenesis

scientific article

Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.

scientific article

Non-invasive force measurement reveals the number of active kinesins on a synaptic vesicle precursor in axonal transport regulated by ARL-8.

scientific article published on 19 January 2018

Phosphatidylinositol 4-phosphate 5-kinase alpha (PIPKα) regulates neuronal microtubule depolymerase kinesin, KIF2A and suppresses elongation of axon branches ⬇️

scientific article published on January 17, 2012

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport ⬇️

scientific article published on July 18, 2011

Streptothricin acetyl transferase 2 (Sat2): A dominant selection marker for Caenorhabditis elegans genome editing.

scientific article published on 9 May 2018

Structural basis for CRMP2-induced axonal microtubule formation

scientific article published on 6 September 2017

The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function

scientific article published in June 2016

The nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegans

scientific article

[The role of kinesin superfamily proteins in morphogenesis]

scientific article published on 01 September 2014

β-Tubulin mutations that cause severe neuropathies disrupt axonal transport ⬇️

scientific article published on March 15, 2013

List of works by Shinsuke Niwa

A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability.

A molecular motor, KIF13A, controls anxiety by transporting the serotonin type 1A receptor.

Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.

BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.

Characterizing KIF16B in neurons reveals a novel intramolecular "stalk inhibition" mechanism that regulates its capacity to potentiate the selective somatodendritic localization of early endosomes.

Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons

KIF19A is a microtubule-depolymerizing kinesin for ciliary length control

KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.

KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth

Kinesin superfamily proteins and the regulation of microtubule dynamics in morphogenesis

Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.

Non-invasive force measurement reveals the number of active kinesins on a synaptic vesicle precursor in axonal transport regulated by ARL-8.

Phosphatidylinositol 4-phosphate 5-kinase alpha (PIPKα) regulates neuronal microtubule depolymerase kinesin, KIF2A and suppresses elongation of axon branches ⬇️

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport ⬇️

Streptothricin acetyl transferase 2 (Sat2): A dominant selection marker for Caenorhabditis elegans genome editing.

Structural basis for CRMP2-induced axonal microtubule formation

The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function

The nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegans

[The role of kinesin superfamily proteins in morphogenesis]

β-Tubulin mutations that cause severe neuropathies disrupt axonal transport ⬇️